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Lea M. Urpa
Lea M. Urpa
Doctoral Researcher, Institute for Molecular Medicine Finland, University of Helsinki
Verified email at helsinki.fi - Homepage
Title
Cited by
Cited by
Year
Sleep alterations following exposure to stress predict fear-associated memory impairments in a rodent model of PTSD
WM Vanderheyden, SA George, L Urpa, M Kehoe, I Liberzon, GR Poe
Experimental brain research 233, 2335-2346, 2015
822015
Focused multidimensional scaling: interactive visualization for exploration of high-dimensional data
LM Urpa, S Anders
BMC bioinformatics 20, 1-8, 2019
222019
Stress-free automatic sleep deprivation using air puffs
BA Gross, WM Vanderheyden, LM Urpa, DE Davis, CJ Fitzpatrick, ...
Journal of neuroscience methods 251, 83-91, 2015
192015
The impact of rare protein coding genetic variation on adult cognitive function
CY Chen, R Tian, T Ge, M Lam, G Sanchez-Andrade, T Singh, L Urpa, ...
Nature Genetics 55 (6), 927-938, 2023
162023
The bradykinin system in stress and anxiety in humans and mice
A Rouhiainen, N Kulesskaya, M Mennesson, Z Misiewicz, T Sipilä, ...
Scientific reports 9 (1), 19437, 2019
142019
Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants
EC Saarentaus, AS Havulinna, N Mars, A Ahola-Olli, TTJ Kiiskinen, ...
Molecular Psychiatry 26 (9), 4884-4895, 2021
82021
A novel variant in SMG9 causes intellectual disability, confirming a role for nonsense-mediated decay components in neurocognitive development
E Rahikkala, L Urpa, B Ghimire, H Topa, MI Kurki, M Koskela, M Airavaara, ...
European Journal of Human Genetics 30 (5), 619-627, 2022
72022
Increase in rem sleep following trauma exposure
W Vanderheyden, L Urpa, G Poe
Sleep Medicine 14, e293, 2013
32013
Evidence for the additivity of rare and common variant burden throughout the spectrum of intellectual disability
L Urpa, MI Kurki, E Rahikkala, E Hämäläinen, V Salomaa, J Suvisaari, ...
European Journal of Human Genetics, 1-8, 2024
12024
Functional Characterization of Six SLCO1B1 (OATP1B1) Variants Observed in Finnish Individuals with a Psychotic Disorder
K Hakkinen, W Kiander, H Kidron, M Lahteenvuo, L Urpa, J Lintunen, ...
Molecular Pharmaceutics 20 (3), 1500-1508, 2023
12023
Genetic contribution to disease-course severity and progression in the SUPER-Finland study, a cohort of 10,403 individuals with psychotic disorders
A Kämpe, J Suvisaari, M Lähteenvuo, T Singh, A Ahola-Olli, L Urpa, ...
Molecular Psychiatry, 1-9, 2024
2024
Genetic Architecture of Intellectual Disability in Northern Finland
L Urpa
Helsingin yliopisto, 2024
2024
W88. PHENOTYPIC AND GENETIC CHARACTERIZATION OF INDIVIDUALS WITH SCHIZOPHRENIA AND HIGH PSYCHIATRIC HOSPITALIZATION BURDEN
A Kämpe, J Suvisaari, M Lähteenvuo, E Vartiainen, T Singh, A Ahola-Olli, ...
European Neuropsychopharmacology 75, S151-S152, 2023
2023
A novel SMG9 variant enriched in the Finnish population causes intellectual disability
E Rahikkala, L Urpa, B Ghimire, H Topa, MI Kurki, M Koskela, M Airavaara, ...
EUROPEAN JOURNAL OF HUMAN GENETICS 31, 172-172, 2023
2023
Enrichment of Rare, Damaging Variants in Schizophrenia-related Genes in Intellectual Disability Patients with Psychotic Disorders
L Urpa, M Kurki, T Singh, E Hamalainen, E Rahikkala, J Moilanen, ...
European Neuropsychopharmacology 63, E45-E45, 2022
2022
Human well-being and capabilities: Thematic Module B
E Oinas, H Katsui, M Jauhola, NHP Korpelainen, P Kuusela, TJ Lammi, ...
2021
CNV Association with Neurodevelopmental Phenotypes in Finnish Population Cohort
E Saarentaus, M Kurki, L Urpa, AS Havulinna, M Perola, V Salomaa, ...
2019
Focused Multidimensional Scaling: An Interactive, User-Friendly Tool for Visualization of Distance Matrices
L Urpa, S Anders
HUMAN HEREDITY 81 (4), 233-233, 2016
2016
Mouse strain-specific differences in transposable element expression following psychosocial stress
LM Urpa
Helsingfors universitet, 2016
2016
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Articles 1–19