| Brick by brick: metabolism and tumor cell growth RJ DeBerardinis, N Sayed, D Ditsworth, CB Thompson Current opinion in genetics & development 18 (1), 54-61, 2008 | 1227 | 2008 |
| Alkylating DNA damage stimulates a regulated form of necrotic cell death WX Zong, D Ditsworth, DE Bauer, ZQ Wang, CB Thompson Genes & development 18 (11), 1272-1282, 2004 | 813 | 2004 |
| ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43 ES Arnold, SC Ling, SC Huelga, C Lagier-Tourenne, M Polymenidou, ... Proceedings of the National Academy of Sciences 110 (8), E736-E745, 2013 | 489 | 2013 |
| Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS K Meyer, L Ferraiuolo, CJ Miranda, S Likhite, S McElroy, S Renusch, ... Proceedings of the National Academy of Sciences 111 (2), 829-832, 2014 | 384 | 2014 |
| Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS KD Foust, DL Salazar, S Likhite, L Ferraiuolo, D Ditsworth, H Ilieva, ... Molecular Therapy 21 (12), 2148-2159, 2013 | 250 | 2013 |
| HIF2α inhibition promotes p53 pathway activity, tumor cell death, and radiation responses JA Bertout, AJ Majmundar, JD Gordan, JC Lam, D Ditsworth, B Keith, ... Proceedings of the National Academy of Sciences 106 (34), 14391-14396, 2009 | 238 | 2009 |
| Activation of poly (ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus D Ditsworth, WX Zong, CB Thompson Journal of Biological Chemistry 282 (24), 17845-17854, 2007 | 231 | 2007 |
| Increased default mode network connectivity in individuals at high familial risk for depression J Posner, J Cha, Z Wang, A Talati, V Warner, A Gerber, BS Peterson, ... Neuropsychopharmacology 41 (7), 1759-1767, 2016 | 214* | 2016 |
| α4 is an essential regulator of PP2A phosphatase activity M Kong, D Ditsworth, T Lindsten, CB Thompson Molecular cell 36 (1), 51-60, 2009 | 204 | 2009 |
| Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS S Sun, Y Sun, SC Ling, L Ferraiuolo, M McAlonis-Downes, Y Zou, ... Proceedings of the National Academy of Sciences 112 (50), E6993-E7002, 2015 | 182 | 2015 |
| Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1 A Israelson, D Ditsworth, S Sun, SW Song, J Liang, M Hruska-Plochan, ... Neuron 86 (1), 218-232, 2015 | 125 | 2015 |
| Oligomerization is a general mechanism for the activation of apoptosis initiator and inflammatory procaspases DW Chang, D Ditsworth, H Liu, SM Srinivasula, ES Alnemri, X Yang Journal of Biological Chemistry 278 (19), 16466-16469, 2003 | 109 | 2003 |
| DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity JL Guerriero, D Ditsworth, JM Catanzaro, G Sabino, MB Furie, RR Kew, ... The Journal of Immunology 186 (6), 3517-3526, 2011 | 96 | 2011 |
| Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS M Bravo-Hernandez, T Tadokoro, MR Navarro, O Platoshyn, Y Kobayashi, ... Nature medicine 26 (1), 118-130, 2020 | 95 | 2020 |
| NF-kappaB: key mediator of inflammation-associated cancer D Ditsworth, WX Zong Cancer biology & therapy 3 (12), 1214-1216, 2004 | 92 | 2004 |
| Apoptotic neuronal death following deep hypothermic circulatory arrest in piglets D Ditsworth, MA Priestley, AW Loepke, C Ramamoorthy, J McCann, ... The Journal of the American Society of Anesthesiologists 98 (5), 1119-1127, 2003 | 75 | 2003 |
| Chemotherapy induces tumor clearance independent of apoptosis JL Guerriero, D Ditsworth, Y Fan, F Zhao, HC Crawford, WX Zong Cancer research 68 (23), 9595-9600, 2008 | 70 | 2008 |
| Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis D Ditsworth, M Maldonado, M McAlonis-Downes, S Sun, A Seelman, ... Acta neuropathologica 133, 907-922, 2017 | 67 | 2017 |
| The PP2A-associated protein α4 plays a critical role in the regulation of cell spreading and migration M Kong, TV Bui, D Ditsworth, JJ Gruber, D Goncharov, VP Krymskaya, ... Journal of biological chemistry 282 (40), 29712-29720, 2007 | 53 | 2007 |
| How do cancer cells acquire the fuel needed to support cell growth? CB Thompson, DE Bauer, JJ Lum, G Hatzivassiliou, WX Zong, F Zhao, ... Cold Spring Harbor symposia on quantitative biology 70, 357-362, 2005 | 46 | 2005 |
