Structure-function relationships in pulmonary surfactant membranes: from biophysics to therapy E Lopez-Rodriguez, J Pérez-Gil Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (6), 1568-1585, 2014 | 294 | 2014 |
Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis D Lutz, A Gazdhar, E Lopez-Rodriguez, C Ruppert, P Mahavadi, ... American journal of respiratory cell and molecular biology 52 (2), 232-243, 2015 | 113 | 2015 |
Meconium impairs pulmonary surfactant by a combined action of cholesterol and bile acids E Lopez-Rodriguez, M Echaide, A Cruz, HW Taeusch, J Perez-Gil Biophysical journal 100 (3), 646-655, 2011 | 71 | 2011 |
Aging exacerbates acute lung injury-induced changes of the air-blood barrier, lung function, and inflammation in the mouse KM Kling, E Lopez-Rodriguez, C Pfarrer, C Mühlfeld, C Brandenberger American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (1 …, 2017 | 70 | 2017 |
Lung surfactant metabolism: early in life, early in disease and target in cell therapy E Lopez-Rodriguez, G Gay-Jordi, A Mucci, N Lachmann, ... Cell and Tissue Research 367, 721-735, 2017 | 65 | 2017 |
Clinical and biological role of secretory phospholipase A2 in acute respiratory distress syndrome infants D De Luca, E Lopez-Rodriguez, A Minucci, F Vendittelli, L Gentile, ... Critical Care 17, 1-12, 2013 | 59 | 2013 |
Alveolar micromechanics in bleomycin-induced lung injury L Knudsen, E Lopez-Rodriguez, L Berndt, L Steffen, C Ruppert, ... American journal of respiratory cell and molecular biology 59 (6), 757-769, 2018 | 56 | 2018 |
Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo E Lopez-Rodriguez, C Boden, M Echaide, J Perez-Gil, M Kolb, J Gauldie, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 310 …, 2016 | 56 | 2016 |
Interfacial behavior and structural properties of a clinical lung surfactant from porcine source O Blanco, A Cruz, OL Ospina, E López-Rodriguez, L Vázquez, J Pérez-Gil Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (11), 2756-2766, 2012 | 51 | 2012 |
Human pulmonary surfactant protein SP-A1 provides maximal efficiency of lung interfacial films E Lopez-Rodriguez, A Pascual, R Arroyo, J Floros, J Perez-Gil Biophysical journal 111 (3), 524-536, 2016 | 50 | 2016 |
iPSC-derived macrophages effectively treat pulmonary alveolar proteinosis in Csf2rb-deficient mice A Mucci, E Lopez-Rodriguez, M Hetzel, S Liu, T Suzuki, C Happle, ... Stem cell reports 11 (3), 696-710, 2018 | 49 | 2018 |
Surfactant replacement therapy reduces acute lung injury and collapse induration-related lung remodeling in the bleomycin model L Steffen, C Ruppert, HG Hoymann, M Funke, S Ebener, C Kloth, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 313 (2 …, 2017 | 48 | 2017 |
On top of the alveolar epithelium: surfactant and the glycocalyx M Ochs, J Hegermann, E Lopez-Rodriguez, S Timm, G Nouailles, ... International journal of molecular sciences 21 (9), 3075, 2020 | 46 | 2020 |
Exposure to polymers reverses inhibition of pulmonary surfactant by serum, meconium, or cholesterol in the captive bubble surfactometer E López-Rodríguez, OL Ospina, M Echaide, HW Taeusch, J Pérez-Gil Biophysical journal 103 (7), 1451-1459, 2012 | 43 | 2012 |
Alveolar dynamics and beyond–the importance of surfactant protein C and cholesterol in lung homeostasis and fibrosis K Sehlmeyer, J Ruwisch, N Roldan, E Lopez-Rodriguez Frontiers in physiology 11, 531383, 2020 | 42 | 2020 |
Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis L Beike, C Wrede, J Hegermann, E Lopez-Rodriguez, C Kloth, J Gauldie, ... Laboratory Investigation 99 (6), 830-852, 2019 | 38 | 2019 |
Linking progression of fibrotic lung remodeling and ultrastructural alterations of alveolar epithelial type II cells in the amiodarone mouse model B Birkelbach, D Lutz, C Ruppert, I Henneke, E Lopez-Rodriguez, ... American journal of physiology-lung cellular and molecular physiology 309 (1 …, 2015 | 38 | 2015 |
In Vitro Functional and Structural Characterization of A Synthetic Clinical Pulmonary Surfactant with Enhanced Resistance to Inhibition M Echaide, C Autilio, E López-Rodríguez, A Cruz, J Pérez-Gil Scientific Reports 10 (1), 1385, 2020 | 26 | 2020 |
Surfactant protein B deficiency induced high surface tension: relationship between alveolar micromechanics, alveolar fluid properties and alveolar epithelial cell injury N Rühl, E Lopez-Rodriguez, K Albert, BJ Smith, TE Weaver, M Ochs, ... International Journal of Molecular Sciences 20 (17), 4243, 2019 | 25 | 2019 |
Air space distension precedes spontaneous fibrotic remodeling and impaired cholesterol metabolism in the absence of surfactant protein C J Ruwisch, K Sehlmeyer, N Roldan, B Garcia-Alvarez, J Perez-Gil, ... American journal of respiratory cell and molecular biology 62 (4), 466-478, 2020 | 23 | 2020 |