Endothelial nitric oxide synthase gene is positively associated with essential hypertension Y Miyamoto, Y Saito, N Kajiyama, M Yoshimura, Y Shimasaki, ... Hypertension 32 (1), 3-8, 1998 | 803 | 1998 |
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling K Kuwahara, Y Wang, J McAnally, JA Richardson, R Bassel-Duby, JA Hill, ... The Journal of clinical investigation 116 (12), 3114-3126, 2006 | 620 | 2006 |
Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction EM Small, JE Thatcher, LB Sutherland, H Kinoshita, RD Gerard, ... Circulation research 107 (2), 294-304, 2010 | 423 | 2010 |
Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy: evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac … M Harada, H Itoh, O Nakagawa, Y Ogawa, Y Miyamoto, K Kuwahara, ... Circulation 96 (10), 3737-3744, 1997 | 327 | 1997 |
Replication protein A1 reduces transcription of the endothelial nitric oxide synthase gene containing a–786T→ C mutation associated with coronary spastic angina Y Miyamoto, Y Saito, M Nakayama, Y Shimasaki, T Yoshimura, ... Human Molecular Genetics 9 (18), 2629-2637, 2000 | 318 | 2000 |
Atrial and brain natriuretic peptides: Hormones secreted from the heart Y Nakagawa, T Nishikimi, K Kuwahara Peptides 111, 18-25, 2019 | 300 | 2019 |
Current biochemistry, molecular biology, and clinical relevance of natriuretic peptides T Nishikimi, K Kuwahara, K Nakao Journal of cardiology 57 (2), 131-140, 2011 | 276 | 2011 |
Muscle-specific signaling mechanism that links actin dynamics to serum response factor K Kuwahara, T Barrientos, GCT Pipes, S Li, EN Olson Molecular and cellular biology 25 (8), 3173-3181, 2005 | 271 | 2005 |
Aldosterone induces angiotensin-converting-enzyme gene expression in cultured neonatal rat cardiocytes E Harada, M Yoshimura, H Yasue, O Nakagawa, M Nakagawa, M Harada, ... Circulation 104 (2), 137-139, 2001 | 266 | 2001 |
NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function K Kuwahara, Y Saito, M Takano, Y Arai, S Yasuno, Y Nakagawa, ... The EMBO journal 22 (23), 6310-6321, 2003 | 254 | 2003 |
Overexpression of brain natriuretic peptide facilitates neutrophil infiltration and cardiac matrix metalloproteinase-9 expression after acute myocardial infarction R Kawakami, Y Saito, I Kishimoto, M Harada, K Kuwahara, N Takahashi, ... Circulation 110 (21), 3306-3312, 2004 | 214 | 2004 |
Involvement of cardiotrophin-1 in cardiac myocyte-nonmyocyte interactions during hypertrophy of rat cardiac myocytes in vitro K Kuwahara, Y Saito, M Harada, M Ishikawa, E Ogawa, Y Miyamoto, ... Circulation 100 (10), 1116-1124, 1999 | 178 | 1999 |
Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart H Kinoshita, K Kuwahara, M Nishida, Z Jian, X Rong, S Kiyonaka, ... Circulation research 106 (12), 1849-1860, 2010 | 176 | 2010 |
Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A M Fujiwara, P Yan, TG Otsuji, G Narazaki, H Uosaki, H Fukushima, ... PloS one 6 (2), e16734, 2011 | 173 | 2011 |
Cardiotrophin-1 phosphorylates akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes K Kuwahara, Y Saito, I Kishimoto, Y Miyamoto, M Harada, E Ogawa, ... Journal of molecular and cellular cardiology 32 (8), 1385-1394, 2000 | 167 | 2000 |
Blockade of the natriuretic peptide receptor guanylyl cyclase-A inhibits NF-κB activation and alleviates myocardial ischemia/reperfusion injury T Izumi, Y Saito, I Kishimoto, M Harada, K Kuwahara, I Hamanaka, ... The Journal of clinical investigation 108 (2), 203-213, 2001 | 159 | 2001 |
The effects of the selective ROCK inhibitor, Y27632, on ET‐1‐induced hypertrophic response in neonatal rat cardiac myocytes–possible involvement of Rho/ROCK pathway in cardiac … K Kuwahara, Y Saito, O Nakagawa, I Kishimoto, M Harada, E Ogawa, ... FEBS letters 452 (3), 314-318, 1999 | 158 | 1999 |
The neuron-restrictive silencer element–neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in … K Kuwahara, Y Saito, E Ogawa, N Takahashi, Y Nakagawa, Y Naruse, ... Molecular and cellular biology 21 (6), 2085-2097, 2001 | 133 | 2001 |
Angiotensin II type 2 receptor deficiency exacerbates heart failure and reduces survival after acute myocardial infarction in mice Y Adachi, Y Saito, I Kishimoto, M Harada, K Kuwahara, N Takahashi, ... Circulation 107 (19), 2406-2408, 2003 | 127 | 2003 |
Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity K Kuwahara, GCT Pipes, J McAnally, JA Richardson, JA Hill, ... The Journal of clinical investigation 117 (5), 1324-1334, 2007 | 123 | 2007 |