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Zhiqiang Ku
Zhiqiang Ku
Westlake University
Verified email at westlake.edu.cn
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Year
Spike mutation D614G alters SARS-CoV-2 fitness
JA Plante, Y Liu, J Liu, H Xia, BA Johnson, KG Lokugamage, X Zhang, ...
Nature 592 (7852), 116-121, 2021
16732021
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis
BA Johnson, X Xie, AL Bailey, B Kalveram, KG Lokugamage, A Muruato, ...
Nature 591 (7849), 293-299, 2021
771*2021
The N501Y spike substitution enhances SARS-CoV-2 infection and transmission
Y Liu, J Liu, KS Plante, JA Plante, X Xie, X Zhang, Z Ku, Z An, D Scharton, ...
Nature 602 (7896), 294-299, 2022
489*2022
Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant
Y Liu, J Liu, BA Johnson, H Xia, Z Ku, C Schindewolf, SG Widen, Z An, ...
Cell reports 39 (7), 2022
3632022
Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape
Z Ku, X Xie, E Davidson, X Ye, H Su, VD Menachery, Y Li, Z Yuan, ...
Nature communications 12 (1), 469, 2021
1572021
Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants
Z Ku, X Xie, PR Hinton, X Liu, X Ye, AE Muruato, DC Ng, S Biswas, J Zou, ...
Nature 595 (7869), 718-723, 2021
1252021
A combination vaccine comprising of inactivated enterovirus 71 and coxsackievirus A16 elicits balanced protective immunity against both viruses
Y Cai, Z Ku, Q Liu, Q Leng, Z Huang
Vaccine 32 (21), 2406-2412, 2014
982014
A virus-like particle vaccine for coxsackievirus A16 potently elicits neutralizing antibodies that protect mice against lethal challenge
Q Liu, K Yan, Y Feng, X Huang, Z Ku, Y Cai, F Liu, J Shi, Z Huang
Vaccine 30 (47), 6642-6648, 2012
892012
Active immunization with a Coxsackievirus A16 experimental inactivated vaccine induces neutralizing antibodies and protects mice against lethal infection
Y Cai, Q Liu, X Huang, D Li, Z Ku, Y Zhang, Z Huang
Vaccine 31 (18), 2215-2221, 2013
852013
A virus-like particle based bivalent vaccine confers dual protection against enterovirus 71 and coxsackievirus A16 infections in mice
Z Ku, Q Liu, X Ye, Y Cai, X Wang, J Shi, D Li, X Jin, W An, Z Huang
Vaccine 32 (34), 4296-4303, 2014
812014
Neutralizing antibodies induced by recombinant virus-like particles of enterovirus 71 genotype C4 inhibit infection at pre-and post-attachment steps
Z Ku, X Ye, X Huang, Y Cai, Q Liu, Y Li, Z Su, Z Huang
PLoS One 8 (2), e57601, 2013
792013
Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms
X Ye, Z Ku, Q Liu, X Wang, J Shi, Y Zhang, L Kong, Y Cong, Z Huang
Journal of virology 88 (1), 72-81, 2014
762014
High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice
C Zhang, Z Ku, Q Liu, X Wang, T Chen, X Ye, D Li, X Jin, Z Huang
Vaccine 33 (20), 2335-2341, 2015
682015
Detection, characterization and quantitation of coxsackievirus A16 using polyclonal antibodies against recombinant capsid subunit proteins
Q Liu, Z Ku, Y Cai, B Sun, Q Leng, Z Huang
Journal of virological methods 173 (1), 115-120, 2011
572011
Transcutaneous immunization via rapidly dissolvable microneedles protects against hand-foot-and-mouth disease caused by enterovirus 71
Z Zhu, X Ye, Z Ku, Q Liu, C Shen, H Luo, H Luan, C Zhang, S Tian, ...
Journal of Controlled Release 243, 291-302, 2016
502016
Structural basis for recognition of human enterovirus 71 by a bivalent broadly neutralizing monoclonal antibody
X Ye, C Fan, Z Ku, T Zuo, L Kong, C Zhang, J Shi, Q Liu, T Chen, Y Zhang, ...
PLoS pathogens 12 (3), e1005454, 2016
482016
Single neutralizing monoclonal antibodies targeting the VP1 GH loop of enterovirus 71 inhibit both virus attachment and internalization during viral entry
Z Ku, X Ye, J Shi, X Wang, Q Liu, Z Huang
Journal of Virology 89 (23), 12084-12095, 2015
482015
Development of murine monoclonal antibodies with potent neutralization effects on enterovirus 71
Z Ku, J Shi, Q Liu, Z Huang
Journal of virological methods 186 (1-2), 193-197, 2012
432012
A bivalent virus-like particle based vaccine induces a balanced antibody response against both enterovirus 71 and norovirus in mice
X Wang, Z Ku, W Dai, T Chen, X Ye, C Zhang, Y Zhang, Q Liu, X Jin, ...
Vaccine 33 (43), 5779-5785, 2015
342015
Oncostatin M Receptor–Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth
A Geethadevi, A Nair, D Parashar, Z Ku, W Xiong, H Deng, Y Li, J George, ...
Cancer research 81 (20), 5336-5352, 2021
332021
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