Genomic evidence for the Pleistocene and recent population history of Native Americans M Raghavan, M Steinrücken, K Harris, S Schiffels, S Rasmussen, ... Science 349 (6250), aab3884, 2015 | 603 | 2015 |
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions AC Fahed, M Wang, JR Homburger, AP Patel, AG Bick, CL Neben, C Lai, ... Nature communications 11 (1), 3635, 2020 | 326 | 2020 |
Genomic insights into the ancestry and demographic history of South America JR Homburger, A Moreno-Estrada, CR Gignoux, D Nelson, E Sanchez, ... PLoS genetics 11 (12), e1005602, 2015 | 262 | 2015 |
Feasibility of obtaining measures of lifestyle from a smartphone app: the MyHeart Counts Cardiovascular Health Study MV McConnell, A Shcherbina, A Pavlovic, JR Homburger, RL Goldfeder, ... JAMA cardiology 2 (1), 67-76, 2017 | 249 | 2017 |
Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation JR Homburger, EM Green, C Caleshu, MS Sunitha, RE Taylor, ... Proceedings of the National Academy of Sciences 113 (24), 6701-6706, 2016 | 119 | 2016 |
Native American gene flow into Polynesia predating Easter Island settlement AG Ioannidis, J Blanco-Portillo, K Sandoval, E Hagelberg, ... Nature 583 (7817), 572-577, 2020 | 115 | 2020 |
Origins and genetic legacies of the Caribbean Taino H Schroeder, M Sikora, S Gopalakrishnan, LM Cassidy, P Maisano Delser, ... Proceedings of the National Academy of Sciences 115 (10), 2341-2346, 2018 | 103 | 2018 |
Cardiopulmonary responses and prognosis in hypertrophic cardiomyopathy: a potential role for comprehensive noninvasive hemodynamic assessment G Finocchiaro, F Haddad, JW Knowles, C Caleshu, A Pavlovic, ... JACC: Heart Failure 3 (5), 408-418, 2015 | 96 | 2015 |
Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores JR Homburger, CL Neben, G Mishne, AY Zhou, S Kathiresan, AV Khera Genome medicine 11, 1-12, 2019 | 92 | 2019 |
Association of genetic variation with cirrhosis: a multi-trait genome-wide association and gene–environment interaction study CA Emdin, M Haas, V Ajmera, TG Simon, J Homburger, C Neben, L Jiang, ... Gastroenterology 160 (5), 1620-1633. e13, 2021 | 88 | 2021 |
Machine learning enables new insights into genetic contributions to liver fat accumulation ME Haas, JP Pirruccello, SN Friedman, M Wang, CA Emdin, VH Ajmera, ... Cell genomics 1 (3), 2021 | 65 | 2021 |
Genomic insights into the origin and diversification of late maritime hunter-gatherers from the Chilean Patagonia C De la Fuente, MC Ávila-Arcos, J Galimany, ML Carpenter, ... Proceedings of the National Academy of Sciences 115 (17), E4006-E4012, 2018 | 62 | 2018 |
Model-driven mitigation measures for reopening schools during the COVID-19 pandemic RS McGee, JR Homburger, HE Williams, CT Bergstrom, AY Zhou Proceedings of the National Academy of Sciences 118 (39), e2108909118, 2021 | 61 | 2021 |
Incident Atrial Fibrillation Is Associated With MYH7 Sarcomeric Gene Variation in Hypertrophic Cardiomyopathy: Results From the International Sarcomeric Human … SP Lee, EA Ashley, J Homburger, C Caleshu, EM Green, D Jacoby, ... Circulation: Heart Failure 11 (9), e005191, 2018 | 56 | 2018 |
Paths and timings of the peopling of Polynesia inferred from genomic networks AG Ioannidis, J Blanco-Portillo, K Sandoval, E Hagelberg, ... Nature 597 (7877), 522-526, 2021 | 39 | 2021 |
In Vivo Post–Cardiac Arrest Myocardial Dysfunction Is Supported by Ca2+/Calmodulin-Dependent Protein Kinase II–Mediated Calcium Long-Term Potentiation and … CE Woods, C Shang, F Taghavi, P Downey, A Zalewski, GR Rubio, J Liu, ... Circulation 134 (13), 961-977, 2016 | 22 | 2016 |
Polygenic background modifies penetrance of monogenic variants conferring risk for coronary artery disease, breast cancer, or colorectal cancer AC Fahed, M Wang, JR Homburger, AP Patel, AG Bick, CL Neben, C Lai, ... medRxiv, 0 | 6 | |
Proactive COVID-19 testing in a partially vaccinated population RS McGee, JR Homburger, HE Williams, CT Bergstrom, AY Zhou medRxiv, 2021.08. 15.21262095, 2021 | 5 | 2021 |
Genetic reduction of muscle glycogen is well tolerated in UK Biobank participants J Homburger, B Cummings, J Ullman, V Ramanan, EM Green, ... Poster session presented at: WORLD Symposium, 2022 | 2 | 2022 |
Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders JC Ullman, KT Mellem, Y Xi, V Ramanan, H Merritt, R Choy, T Gujral, ... Science Translational Medicine 16 (730), eadf1691, 2024 | 1 | 2024 |