| CAR T cells targeting B7-H3, a pan-cancer antigen, demonstrate potent preclinical activity against pediatric solid tumors and brain tumors RG Majzner, JL Theruvath, A Nellan, S Heitzeneder, Y Cui, CW Mount, ... Clinical Cancer Research 25 (8), 2560-2574, 2019 | 448 | 2019 |
| Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance JKM Lim, A Delaidelli, SW Minaker, HF Zhang, M Colovic, H Yang, ... Proceedings of the National Academy of Sciences 116 (19), 9433-9442, 2019 | 229 | 2019 |
| Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors J Theruvath, E Sotillo, CW Mount, CM Graef, A Delaidelli, S Heitzeneder, ... Nature medicine 26 (5), 712-719, 2020 | 205 | 2020 |
| Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma LK Donovan, A Delaidelli, SK Joseph, K Bielamowicz, K Fousek, ... Nature medicine 26 (5), 720-731, 2020 | 165 | 2020 |
| Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication J Theruvath, M Menard, BAH Smith, MH Linde, GL Coles, GN Dalton, ... Nature medicine 28 (2), 333-344, 2022 | 125 | 2022 |
| Targeting hypoxia-induced carbonic anhydrase IX enhances immune-checkpoint blockade locally and systemically SC Chafe, PC McDonald, S Saberi, O Nemirovsky, G Venkateswaran, ... Cancer immunology research 7 (7), 1064-1078, 2019 | 119 | 2019 |
| GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity S Heitzeneder, KR Bosse, Z Zhu, D Zhelev, RG Majzner, MT Radosevich, ... Cancer Cell 40 (1), 53-69. e9, 2022 | 92 | 2022 |
| Metabolic regulation of the epigenome drives lethal infantile ependymoma KA Michealraj, SA Kumar, LJY Kim, FMG Cavalli, D Przelicki, JB Wojcik, ... Cell 181 (6), 1329-1345. e24, 2020 | 92 | 2020 |
| Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery SH Chiou, D Tseng, A Reuben, V Mallajosyula, IS Molina, S Conley, ... Immunity 54 (3), 586-602. e8, 2021 | 89 | 2021 |
| Class I HDAC inhibitors enhance YB‐1 acetylation and oxidative stress to block sarcoma metastasis AM El‐Naggar, SP Somasekharan, Y Wang, H Cheng, GL Negri, M Pan, ... EMBO reports 20 (12), e48375, 2019 | 84 | 2019 |
| Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity A Jan, B Jansonius, A Delaidelli, F Bhanshali, YA An, N Ferreira, ... Acta neuropathologica communications 6, 1-17, 2018 | 59 | 2018 |
| Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma HF Zhang, CS Hughes, W Li, JZ He, D Surdez, AM El-Naggar, H Cheng, ... Cancer discovery 11 (11), 2884-2903, 2021 | 53 | 2021 |
| eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response A Jan, B Jansonius, A Delaidelli, SP Somasekharan, F Bhanshali, ... Acta Neuropathologica 133, 101-119, 2017 | 52 | 2017 |
| Navigated intraoperative 2-dimensional ultrasound in high-grade glioma surgery: impact on extent of resection and patient outcome A Moiraghi, F Prada, A Delaidelli, R Guatta, A May, A Bartoli, M Saini, ... Operative Neurosurgery 18 (4), 363-373, 2020 | 43 | 2020 |
| Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma GL Negri, BM Grande, A Delaidelli, A El‐Naggar, D Cochrane, CC Lau, ... The Journal of pathology 249 (3), 319-331, 2019 | 42 | 2019 |
| MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation A Delaidelli, GL Negri, A Jan, B Jansonius, A El-Naggar, JKM Lim, ... Cell Death & Differentiation 24 (9), 1564-1576, 2017 | 30 | 2017 |
| Translational control in brain pathologies: biological significance and therapeutic opportunities A Delaidelli, A Jan, J Herms, PH Sorensen Acta Neuropathologica 137, 535-555, 2019 | 28 | 2019 |
| Respiration: a new mechanism for CSF circulation? A Delaidelli, A Moiraghi Journal of Neuroscience 37 (30), 7076-7078, 2017 | 26 | 2017 |
| α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response A Delaidelli, M Richner, L Jiang, A van der Laan, ... Acta Neuropathologica Communications 9, 1-16, 2021 | 21 | 2021 |
| Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors JB Foster, C Griffin, JL Rokita, A Stern, C Brimley, K Rathi, MV Lane, ... Journal for Immunotherapy of Cancer 10 (9), 2022 | 19 | 2022 |
