| OPUS-PSP: an orientation-dependent statistical all-atom potential derived from side-chain packing M Lu, AD Dousis, J Ma Journal of molecular biology 376 (1), 288-301, 2008 | 207 | 2008 |
| OPUS‐Rota: A fast and accurate method for side‐chain modeling M Lu, AD Dousis, J Ma Protein Science 17 (9), 1576-1585, 2008 | 68 | 2008 |
| In vitro transcription methods and constructs J Chen, A Dousis US Patent 10,465,190, 2019 | 49 | 2019 |
| RNA polymerase variants AE Rabideau, A Dousis, K Ravichandran, E Hobert US Patent 10,526,629, 2020 | 48 | 2020 |
| An engineered T7 RNA polymerase that produces mRNA free of immunostimulatory byproducts A Dousis, K Ravichandran, EM Hobert, MJ Moore, AE Rabideau Nature biotechnology 41 (4), 560-568, 2023 | 47 | 2023 |
| mRNA therapy restores euglycemia and prevents liver tumors in murine model of glycogen storage disease J Cao, M Choi, E Guadagnin, M Soty, M Silva, V Verzieux, E Weisser, ... Nature Communications 12 (1), 3090, 2021 | 47 | 2021 |
| Polynucleotides encoding relaxin B Ticho, N Briancon-Eris, Z Xia, A Dousis, S De Picciotto, V Presnyak, ... US Patent 10,730,924, 2020 | 40 | 2020 |
| Normal-mode refinement of anisotropic thermal parameters for potassium channel KcsA at 3.2 Å crystallographic resolution X Chen, BK Poon, A Dousis, Q Wang, J Ma Structure 15 (8), 955-962, 2007 | 31 | 2007 |
| Therapeutic enzyme engineering using a generative neural network A Giessel, A Dousis, K Ravichandran, K Smith, S Sur, I McFadyen, ... Scientific Reports 12 (1), 1536, 2022 | 29 | 2022 |
| Variational autoencoder for biological sequence generation A Giessel, A Dousis, I McFadyen US Patent App. 17/145,164, 2021 | 28 | 2021 |
| RNA polymerase variants for co-transcriptional capping A Dousis, K Ravichandran, AE Rabideau, M Franklin, K Smith, ML Hall US Patent 11,485,960, 2022 | 19 | 2022 |
| OPUS-Dom: applying the folding-based method VECFOLD to determine protein domain boundaries Y Wu, AD Dousis, M Chen, J Li, J Ma Journal of molecular biology 385 (4), 1314-1329, 2009 | 19 | 2009 |
| Predicting protein folding cores by empirical potential functions M Chen, AD Dousis, Y Wu, P Wittung-Stafshede, J Ma Archives of biochemistry and biophysics 483 (1), 16-22, 2009 | 11 | 2009 |
| Ionizable amino lipids distribution and effects on DSPC/cholesterol membranes: implications for lipid nanoparticle structure S Dehghani-Ghahnaviyeh, M Smith, Y Xia, A Dousis, A Grossfield, S Sur The Journal of Physical Chemistry B 127 (31), 6928-6939, 2023 | 6 | 2023 |
| mRNA Therapy for the treatment of glycogen storage disease type 1a (GSD1a) J Cao, M Choi, A Markel, J Zhou, S Liang, S Liang, A Frassetto, L Rice, ... MOLECULAR THERAPY 27 (4), 369-370, 2019 | 2 | 2019 |
| Phenylalanine hydroxylase variants and uses thereof LM Rice, P Finn, A Dousis US Patent App. 17/928,680, 2023 | 1 | 2023 |
| Amnio acid substitution at position 298 of human glucose-6 phosphatase-α significantly impacts its stability in mammalian cells J Cao, A Markel, E Hanahoe, T Ketova, C Mihai, Z Zalinger, D Marquardt, ... Amino Acids 55 (5), 695-708, 2023 | 1 | 2023 |
| RNA polymerase variants AE Rabideau, A Dousis, K Ravichandran, E Hobert US Patent 11,066,686, 2021 | 1 | 2021 |
| Rna polymerase variants AE Rabideau, A Dousis, K Ravichandran, E Hobert US Patent App. 18/448,856, 2024 | | 2024 |
| Polynucleotides encoding phenylalanine hydroxylase for the treatment of phenylketonuria R Rajendran, P Finn, PGV Martini, D An, A Dousis, K Ravichandran US Patent 11,939,601, 2024 | | 2024 |
Mingyang LuNortheastern University; Jackson Laboratory; Tufts University School of MedicineVerified email at northeastern.edu
