VHH, bivalent domains and chimeric heavy chain-only antibodies with high neutralizing efficacy for scorpion toxin AahI′ I Hmila, D Saerens, Z Benlasfar, K Conrath, M El Ayeb, S Muyldermans, ... Molecular immunology 45 (14), 3847-3856, 2008 | 158 | 2008 |
A bispecific nanobody to provide full protection against lethal scorpion envenoming I Hmila, D Saerens, RB Abderrazek, C Vincke, N Abidi, Z Benlasfar, ... The FASEB Journal 24 (9), 3479-3489, 2010 | 146 | 2010 |
Identification of potent nanobodies to neutralize the most poisonous polypeptide from scorpion venom RB Abderrazek, I Hmila, C Vincke, Z Benlasfar, M Pellis, H Dabbek, ... Biochemical Journal 424 (2), 263-272, 2009 | 79 | 2009 |
Antibodies against alpha‐synuclein: tools and therapies NN Vaikath, I Hmila, V Gupta, D Erskine, M Ingelsson, OMA El‐Agnaf Journal of Neurochemistry 150 (5), 612-625, 2019 | 66 | 2019 |
Pre-clinical studies of toxin-specific Nanobodies: Evidence of in vivo efficacy to prevent fatal disturbances provoked by scorpion envenoming I Hmila, B Cosyns, H Tounsi, B Roosens, V Caveliers, RB Abderrazek, ... Toxicology and applied pharmacology 264 (2), 222-231, 2012 | 41 | 2012 |
Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII scorpion toxin R Ben Abderrazek, C Vincke, I Hmila, D Saerens, N Abidi, M El Ayeb, ... Protein Engineering, Design & Selection 24 (9), 727-735, 2011 | 40 | 2011 |
A multiplex real-time RT-PCR for simultaneous detection of four most common avian respiratory viruses N Laamiri, R Aouini, B Marnissi, A Ghram, I Hmila Virology 515, 29-37, 2018 | 36 | 2018 |
Efficient expression of the anti‐AahI' scorpion toxin nanobody under a new functional form in a Pichia pastoris system A Ezzine, S M'Hirsi el Adab, B Bouhaouala‐Zahar, I Hmila, L Baciou, ... Biotechnology and applied biochemistry 59 (1), 15-21, 2012 | 34 | 2012 |
A novel method for detection of H9N2 influenza viruses by an aptamer-real time-PCR I Hmila, M Wongphatcharachai, N Laamiri, R Aouini, B Marnissi, M Arbi, ... Journal of virological methods 243, 83-91, 2017 | 30 | 2017 |
Accurate detection of avian respiratory viruses by use of multiplex PCR-based luminex suspension microarray assay N Laamiri, P Fällgren, S Zohari, J Ben Ali, A Ghram, M Leijon, I Hmila Journal of Clinical Microbiology 54 (11), 2716-2725, 2016 | 26 | 2016 |
Novel engineered nanobodies specific for N‐terminal region of alpha‐synuclein recognize Lewy‐body pathology and inhibit in‐vitro seeded aggregation and toxicity I Hmila, NN Vaikath, NK Majbour, D Erskine, IP Sudhakaran, V Gupta, ... The FEBS Journal 289 (15), 4657-4673, 2022 | 14 | 2022 |
Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity V Gupta, S Salim, I Hmila, NN Vaikath, IP Sudhakaran, SS Ghanem, ... Scientific reports 10 (1), 8137, 2020 | 12 | 2020 |
Immunological aspects of scorpion toxins: current status and perspectives B Bouhaouala-Zahar, R Ben Abderrazek, I Hmila, N Abidi, ... Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets …, 2011 | 12 | 2011 |
Effectiveness of the Androctonus australis hector nanobody Nbf12-10 antivenom to neutralize significantly the toxic effect and tissue damage provoked by fraction of Androctonus … F Chgoury, R Benabderrazek, H Tounsi, N Oukkache, I Hmila Biochem. Pharmacol.(Los Angel) 4, 1-8, 2015 | 10 | 2015 |
Expression, purification and characterization of α-synuclein fibrillar specific scFv from inclusion bodies V Gupta, IP Sudhakaran, Z Islam, NN Vaikath, I Hmila, T Lukacsovich, ... PloS one 15 (11), e0241773, 2020 | 9 | 2020 |
Generation of ssDNA aptamers as diagnostic tool for Newcastle avian virus Boutheina Marnissi, Masood Kamali-Moghaddam, Abdeljelil Ghram, Issam Hmila PLoS ONE, 2020 | 8 | 2020 |
Inhibition of α-Synuclein Seeding-Dependent Aggregation by ssDNA Aptamers Specific to C-Terminally Truncated α-Synuclein Fibrils I Hmila, IP Sudhakaran, SS Ghanem, NN Vaikath, I Poggiolini, ... ACS Chemical Neuroscience 13 (23), 3330-3341, 2022 | 5 | 2022 |
Accurate detection of Newcastle disease virus using proximity‐dependent DNA aptamer ligation assays B Marnissi, K Khalfaoui, T Ebai, F Marques Souza de Oliveira, A Ghram, ... FEBS Open bio 11 (4), 1122-1131, 2021 | 5 | 2021 |
Hyalomma dromedarii (Acari: Ixodidae) Salivary Gland Extract Inhibits Angiogenesis and Exhibits In Vitro Antitumor Effects C Bensaoud, Z Abdelkafi-Koubaa, H Ben Mabrouk, M Morjen, I Hmila, ... Journal of medical entomology 54 (6), 1476-1482, 2017 | 5 | 2017 |
Ben-Abderrazek Ben-Abdallah R, Saerens D, Benlasfar Z, Conrath K, Ayeb ME, Muyldermans S, Bouhaouala-Zahar B: VHH, bivalent domains and chimeric Heavy chain-only antibodies … I Hmila Mol Immunol 45, 3847-3856, 2008 | 3 | 2008 |