Follow
Issam HMILA
Issam HMILA
Biologiste IPT
Verified email at pasteur.tn
Title
Cited by
Cited by
Year
VHH, bivalent domains and chimeric heavy chain-only antibodies with high neutralizing efficacy for scorpion toxin AahI′
I Hmila, D Saerens, Z Benlasfar, K Conrath, M El Ayeb, S Muyldermans, ...
Molecular immunology 45 (14), 3847-3856, 2008
1582008
A bispecific nanobody to provide full protection against lethal scorpion envenoming
I Hmila, D Saerens, RB Abderrazek, C Vincke, N Abidi, Z Benlasfar, ...
The FASEB Journal 24 (9), 3479-3489, 2010
1462010
Identification of potent nanobodies to neutralize the most poisonous polypeptide from scorpion venom
RB Abderrazek, I Hmila, C Vincke, Z Benlasfar, M Pellis, H Dabbek, ...
Biochemical Journal 424 (2), 263-272, 2009
792009
Antibodies against alpha‐synuclein: tools and therapies
NN Vaikath, I Hmila, V Gupta, D Erskine, M Ingelsson, OMA El‐Agnaf
Journal of Neurochemistry 150 (5), 612-625, 2019
662019
Pre-clinical studies of toxin-specific Nanobodies: Evidence of in vivo efficacy to prevent fatal disturbances provoked by scorpion envenoming
I Hmila, B Cosyns, H Tounsi, B Roosens, V Caveliers, RB Abderrazek, ...
Toxicology and applied pharmacology 264 (2), 222-231, 2012
412012
Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII scorpion toxin
R Ben Abderrazek, C Vincke, I Hmila, D Saerens, N Abidi, M El Ayeb, ...
Protein Engineering, Design & Selection 24 (9), 727-735, 2011
402011
A multiplex real-time RT-PCR for simultaneous detection of four most common avian respiratory viruses
N Laamiri, R Aouini, B Marnissi, A Ghram, I Hmila
Virology 515, 29-37, 2018
362018
Efficient expression of the anti‐AahI' scorpion toxin nanobody under a new functional form in a Pichia pastoris system
A Ezzine, S M'Hirsi el Adab, B Bouhaouala‐Zahar, I Hmila, L Baciou, ...
Biotechnology and applied biochemistry 59 (1), 15-21, 2012
342012
A novel method for detection of H9N2 influenza viruses by an aptamer-real time-PCR
I Hmila, M Wongphatcharachai, N Laamiri, R Aouini, B Marnissi, M Arbi, ...
Journal of virological methods 243, 83-91, 2017
302017
Accurate detection of avian respiratory viruses by use of multiplex PCR-based luminex suspension microarray assay
N Laamiri, P Fällgren, S Zohari, J Ben Ali, A Ghram, M Leijon, I Hmila
Journal of Clinical Microbiology 54 (11), 2716-2725, 2016
262016
Novel engineered nanobodies specific for N‐terminal region of alpha‐synuclein recognize Lewy‐body pathology and inhibit in‐vitro seeded aggregation and toxicity
I Hmila, NN Vaikath, NK Majbour, D Erskine, IP Sudhakaran, V Gupta, ...
The FEBS Journal 289 (15), 4657-4673, 2022
142022
Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity
V Gupta, S Salim, I Hmila, NN Vaikath, IP Sudhakaran, SS Ghanem, ...
Scientific reports 10 (1), 8137, 2020
122020
Immunological aspects of scorpion toxins: current status and perspectives
B Bouhaouala-Zahar, R Ben Abderrazek, I Hmila, N Abidi, ...
Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets …, 2011
122011
Effectiveness of the Androctonus australis hector nanobody Nbf12-10 antivenom to neutralize significantly the toxic effect and tissue damage provoked by fraction of Androctonus …
F Chgoury, R Benabderrazek, H Tounsi, N Oukkache, I Hmila
Biochem. Pharmacol.(Los Angel) 4, 1-8, 2015
102015
Expression, purification and characterization of α-synuclein fibrillar specific scFv from inclusion bodies
V Gupta, IP Sudhakaran, Z Islam, NN Vaikath, I Hmila, T Lukacsovich, ...
PloS one 15 (11), e0241773, 2020
92020
Generation of ssDNA aptamers as diagnostic tool for Newcastle avian virus
Boutheina Marnissi, Masood Kamali-Moghaddam, Abdeljelil Ghram, Issam Hmila
PLoS ONE, 2020
82020
Inhibition of α-Synuclein Seeding-Dependent Aggregation by ssDNA Aptamers Specific to C-Terminally Truncated α-Synuclein Fibrils
I Hmila, IP Sudhakaran, SS Ghanem, NN Vaikath, I Poggiolini, ...
ACS Chemical Neuroscience 13 (23), 3330-3341, 2022
52022
Accurate detection of Newcastle disease virus using proximity‐dependent DNA aptamer ligation assays
B Marnissi, K Khalfaoui, T Ebai, F Marques Souza de Oliveira, A Ghram, ...
FEBS Open bio 11 (4), 1122-1131, 2021
52021
Hyalomma dromedarii (Acari: Ixodidae) Salivary Gland Extract Inhibits Angiogenesis and Exhibits In Vitro Antitumor Effects
C Bensaoud, Z Abdelkafi-Koubaa, H Ben Mabrouk, M Morjen, I Hmila, ...
Journal of medical entomology 54 (6), 1476-1482, 2017
52017
Ben-Abderrazek Ben-Abdallah R, Saerens D, Benlasfar Z, Conrath K, Ayeb ME, Muyldermans S, Bouhaouala-Zahar B: VHH, bivalent domains and chimeric Heavy chain-only antibodies …
I Hmila
Mol Immunol 45, 3847-3856, 2008
32008
The system can't perform the operation now. Try again later.
Articles 1–20