Sigma-1 receptor agonists induce oxidative stress in mitochondria and enhance complex I activity in physiological condition but protect against pathological oxidative stress N Goguadze, E Zhuravliova, D Morin, D Mikeladze, T Maurice Neurotoxicity Research 35, 1-18, 2019 | 74 | 2019 |
Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondria N Natsvlishvili, N Goguadze, E Zhuravliova, D Mikeladze BMC biochemistry 16, 1-7, 2015 | 71 | 2015 |
Creatine enhances survival of glutamate‐treated neuronal/glial cells, modulates Ras/NF‐κB signaling, and increases the generation of reactive oxygen species E Juravleva, T Barbakadze, D Mikeladze, T Kekelidze Journal of neuroscience research 79 (1‐2), 224-230, 2005 | 59 | 2005 |
Haloperidol induces neurotoxicity by the NMDA receptor downstream signaling pathway, alternative from glutamate excitotoxicity E Zhuravliova, T Barbakadze, N Natsvlishvili, DG Mikeladze Neurochemistry international 50 (7-8), 976-982, 2007 | 45 | 2007 |
Social isolation in rats inhibits oxidative metabolism, decreases the content of mitochondrial K-Ras and activates mitochondrial hexokinase E Zhuravliova, T Barbakadze, E Zaalishvili, M Chipashvili, N Koshoridze, ... Behavioural brain research 205 (2), 377-383, 2009 | 43 | 2009 |
N-Methyl-D-Aspartate and σ-Ligands Change the Production of Interleukins 8 and 10 in Lymphocytes through Modulation of the NMDA Glutamate Receptor E Kvaratskhelia, E Maisuradze, NG Dabrundashvili, N Natsvlishvili, ... Neuroimmunomodulation 16 (3), 201-207, 2009 | 33 | 2009 |
Nobiletin restores impaired hippocampal mitochondrial bioenergetics in hypothyroidism through activation of matrix substrate-level phosphorylation N Jojua, N Sharikadze, E Zhuravliova, E Zaalishvili, DG Mikeladze Nutritional Neuroscience 18 (5), 225-231, 2015 | 17 | 2015 |
Inhibition of nitric oxide synthase and farnesyltransferase change the activities of several transcription factors E Zhuravliova, T Barbakadze, N Narmania, J Ramsden, D Mikeladze Journal of molecular neuroscience 31, 281-287, 2007 | 17 | 2007 |
Gut neurotoxin p-cresol induces differential expression of GLUN2B and GLUN2A subunits of the NMDA receptor in the hippocampus and nucleus accumbens in healthy and audiogenic … G Tevzadze, E Zhuravliova, T Barbakadze, L Shanshiashvili, ... AIMS neuroscience 7 (1), 30, 2020 | 14 | 2020 |
Synaptic and non-synaptic mitochondria in hippocampus of adult rats differ in their sensitivity to hypothyroidism E Zhuravliova, T Barbakadze, N Jojua, E Zaalishvili, L Shanshiashvili, ... Cellular and molecular neurobiology 32, 1311-1321, 2012 | 11 | 2012 |
S-nitrosylation decreases the adsorption of H-Ras in lipid bilayer and changes intrinsic catalytic activity L Shanshiashvili, N Narmania, T Barbakadze, E Zhuravliova, ... Cell biochemistry and biophysics 59, 191-199, 2011 | 11 | 2011 |
Effects of a gut microbiome toxin, p-cresol, on the indices of social behavior in rats G Tevzadze, N Oniani, E Zhuravliova, N Darchia, M Eliozishvili, ... Neurophysiology 50, 372-377, 2018 | 10 | 2018 |
Mitochondrial target of nobiletin's action N Sharikadze, N Jojua, M Sepashvili, E Zhuravliova, DG Mikeladze Natural Product Communications 11 (12), 1934578X1601101215, 2016 | 7 | 2016 |
Hypoinsulinemia alleviates the GRF1/Ras/Akt anti-apoptotic pathway and induces alterations of mitochondrial ras trafficking in neuronal cells E Zhuravliova, T Barbakadze, N Narmania, M Sepashvili, DG Mikeladze Neurochemical research 34, 1076-1082, 2009 | 7 | 2009 |
Effects of a gut microbiome toxin, p-Cresol, on the susceptibility to seizures in rats G Tevzadze, Z Nanobashvili, E Zhuravliova, I Bilanishvili, ... Neurophysiology 50, 424-427, 2018 | 6 | 2018 |
Nobiletin transiently increases the production of nitric oxide and changes the activity of succinate dehydrogenase in human blood lymphocytes NG Dabrundashvili, EB Kvaratskhelia, M Gagua, E Maisuradze, ... Journal of Food Biochemistry 35 (2), 638-649, 2011 | 6 | 2011 |
Production of homocysteine in serum-starved apoptotic PC12 cells depends on the activation and modification of Ras T Barbakadze, E Zhuravliova, M Sepashvili, E Zaalishvili, JJ Ramsden, ... Neuroscience letters 391 (1-2), 56-61, 2005 | 6 | 2005 |
Gut neurotoxin p-cresol induces brain-derived neurotrophic factor secretion and increases the expression of neurofilament subunits in PC-12 cells G Tevzadze, T Barbakadze, E Kvergelidze, E Zhuravliova, ... AIMS neuroscience 9 (1), 12, 2022 | 5 | 2022 |
mGluR1 interacts with cystic fibrosis transmembrane conductance regulator and modulates the secretion of IL-10 in cystic fibrosis peripheral lymphocytes LV Shanshiashvili, N Dabrundashvili, N Natsvlishvili, E Kvaratskhelia, ... Molecular Immunology 51 (3-4), 310-315, 2012 | 5 | 2012 |
Creatine Prevents the Cytotoxicity of Haloperidol by Alteration of NO/Ras/NF-kappaB System E Juravleva, T Barbakadze, N Natsvlishvili, T Kekelidze, D Mikeladze NATO SCIENCE SERIES SUB SERIES I LIFE AND BEHAVIOURAL SCIENCES 342, 113-124, 2003 | 5 | 2003 |