Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness F Hulpia, D Mabille, GD Campagnaro, G Schumann, L Maes, I Roditi, ... Nature communications 10 (1), 5564, 2019 | 60 | 2019 |
Revisiting tubercidin against kinetoplastid parasites: Aromatic substitutions at position 7 improve activity and reduce toxicity F Hulpia, GD Campagnaro, M Scortichini, K Van Hecke, L Maes, ... European Journal of Medicinal Chemistry 164, 689-705, 2019 | 47 | 2019 |
C6–O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents F Hulpia, J Bouton, GD Campagnaro, IA Alfayez, D Mabille, L Maes, ... European Journal of Medicinal Chemistry 188, 112018, 2020 | 35 | 2020 |
Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes M Zoltner, GD Campagnaro, G Taleva, A Burrell, M Cerone, KF Leung, ... Journal of Biological Chemistry 295 (24), 8331-8347, 2020 | 33 | 2020 |
Trypanosoma brucei inhibition by essential oils from medicinal and aromatic plants traditionally used in Cameroon (Azadirachta indica, Aframomum melegueta, Aframomum daniellii … SL Ngahang Kamte, F Ranjbarian, GD Campagnaro, PC Biapa Nya, ... International Journal of Environmental Research and Public Health 14 (7), 737, 2017 | 33 | 2017 |
Purine and pyrimidine transporters of pathogenic protozoa–conduits for therapeutic agents GD Campagnaro, HP De Koning Medicinal Research Reviews 40 (5), 1679-1714, 2020 | 24 | 2020 |
Structure–Activity Relationship Exploration of 3′-Deoxy-7-deazapurine Nucleoside Analogues as Anti-Trypanosoma brucei Agents F Hulpia, GD Campagnaro, KJ Alzahrani, IA Alfayez, MA Ungogo, ... ACS Infectious Diseases 6 (8), 2045-2056, 2020 | 24 | 2020 |
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei AH Alghamdi, JC Munday, GD Campagnaro, D Gurvic, F Svensson, ... Elife 9, e56416, 2020 | 21 | 2020 |
Cloning and characterisation of the Equilibrative Nucleoside Transporter family of Trypanosoma cruzi: Ultra-high affinity and selectivity to survive in the intracellular niche GD Campagnaro, J de Freitas Nascimento, RBM Girard, AM Silber, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (12), 2750-2763, 2018 | 19 | 2018 |
Diminazene resistance in Trypanosoma congolense is not caused by reduced transport capacity but associated with reduced mitochondrial membrane potential LV Carruthers, JC Munday, GU Ebiloma, P Steketee, S Jayaraman, ... Molecular Microbiology 116 (2), 564-588, 2021 | 15 | 2021 |
Trypanosoma brucei bloodstream forms express highly specific and separate transporters for adenine and hypoxanthine; evidence for a new protozoan purine transporter family? GD Campagnaro, KJ Alzahrani, JC Munday, HP De Koning Molecular and biochemical parasitology 220, 46-56, 2018 | 15 | 2018 |
Nucleoside Transport and Nucleobase Uptake Null Mutants in Leishmania mexicana for the Routine Expression and Characterization of Purine and Pyrimidine … MM Aldfer, TA AlSiari, HAA Elati, MJ Natto, IA Alfayez, GD Campagnaro, ... International Journal of Molecular Sciences 23 (15), 8139, 2022 | 10 | 2022 |
Differences in transporters rather than drug targets are the principal determinants of the different innate sensitivities of Trypanosoma congolense and Trypanozoon subgenus … MA Ungogo, GD Campagnaro, AH Alghamdi, MJ Natto, HP de Koning International Journal of Molecular Sciences 23 (5), 2844, 2022 | 10 | 2022 |
A Toxoplasma gondii Oxopurine Transporter Binds Nucleobases and Nucleosides Using Different Binding Modes GD Campagnaro, HAA Elati, S Balaska, ME Martin Abril, MJ Natto, ... International Journal of Molecular Sciences 23 (2), 710, 2022 | 9 | 2022 |
Arginine methyltransferases as regulators of RNA-binding protein activities in pathogenic kinetoplastids GD Campagnaro, E Nay, MJ Plevin, AK Cruz, PB Walrad Frontiers in Molecular Biosciences 8, 692668, 2021 | 7 | 2021 |
Functional Study of Leishmania braziliensis Protein Arginine Methyltransferases (PRMTs) Reveals That PRMT1 and PRMT5 Are Required for Macrophage Infection L Lorenzon, JC Quilles Jr, GD Campagnaro, L Azevedo Orsine, L Almeida, ... ACS Infectious Diseases 8 (3), 516-532, 2022 | 4 | 2022 |
Purine transporters as efficient carriers for anti-kinetoplastid molecules: 3′-Deoxytubercidin versus trypanosomes GD Campagnaro ACS Infectious Diseases 8 (9), 1727-1730, 2022 | 2 | 2022 |
Genetic and functional dissection of the glutamate-proline pathway reveals a shortcut for glutamate catabolism in Leishmania GD Campagnaro, AK Cruz bioRxiv, 2024.02. 06.579205, 2024 | | 2024 |
Overexpression of Leishmania major protein arginine methyltransferase 6 reduces parasite infectivity in vivo GD Campagnaro, LB Lorenzon, MA Rodrigues, TPA Defina, CF Pinzan, ... Acta Tropica 244, 106959, 2023 | | 2023 |
Leishmania braziliensis Protein Arginine Methyltransferases interactomes L Lorenzon, JC Quilles Junior, GD Campagnaro, LA Orsine, L Almeida, ... Angela Kaysel Cruz-University of São Paulo, 2022 | | 2022 |