| Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain MR Owen, E Doran, AP Halestrap Biochemical journal 348 (3), 607-614, 2000 | 2525 | 2000 |
| Role of calcium ions in regulation of mammalian intramitochondrial metabolism JG McCormack, AP Halestrap, RM Denton Physiological reviews 70 (2), 391-425, 1990 | 1650 | 1990 |
| Mitochondrial permeability transition pore opening during myocardial reperfusion—a target for cardioprotection AP Halestrap, SJ Clarke, SA Javadov Cardiovascular research 61 (3), 372-385, 2004 | 1645 | 2004 |
| The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation AP Halestrap, NT PRICE Biochemical Journal 343 (2), 281-299, 1999 | 1609 | 1999 |
| The SLC16 gene family—from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond AP Halestrap, D Meredith Pflügers Archiv 447, 619-628, 2004 | 1266 | 2004 |
| What is the mitochondrial permeability transition pore? AP Halestrap Journal of molecular and cellular cardiology 46 (6), 821-831, 2009 | 1169 | 2009 |
| Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion EJ Griffiths, AP Halestrap Biochemical Journal 307 (1), 93-98, 1995 | 1126 | 1995 |
| The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1α-dependent mechanism MS Ullah, AJ Davies, AP Halestrap Journal of Biological Chemistry 281 (14), 9030-9037, 2006 | 1078 | 2006 |
| The permeability transition pore complex: another view AP Halestrap, GP McStay, SJ Clarke Biochimie 84 (2-3), 153-166, 2002 | 976 | 2002 |
| Transport of lactate and other monocarboxylates across mammalian plasma membranes RC Poole, AP Halestrap American Journal of Physiology-Cell Physiology 264 (4), C761-C782, 1993 | 897 | 1993 |
| Inhibition of Ca2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl … AP Halestrap, AM Davidson Biochemical Journal 268 (1), 153-160, 1990 | 894 | 1990 |
| Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter ECH Friesema, S Ganguly, A Abdalla, JEM Fox, AP Halestrap, TJ Visser Journal of Biological Chemistry 278 (41), 40128-40135, 2003 | 820 | 2003 |
| CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression P Kirk, MC Wilson, C Heddle, MH Brown, AN Barclay, AP Halestrap The EMBO journal, 2000 | 795 | 2000 |
| The monocarboxylate transporter family—structure and functional characterization AP Halestrap IUBMB life 64 (1), 1-9, 2012 | 792 | 2012 |
| The monocarboxylate transporter family—role and regulation AP Halestrap, MC Wilson IUBMB life 64 (2), 109-119, 2012 | 774 | 2012 |
| Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation ECH Friesema, A Grueters, H Biebermann, H Krude, A Von Moers, ... The Lancet 364 (9443), 1435-1437, 2004 | 748 | 2004 |
| Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase AP Halestrap, KY Woodfield, CP Connern Journal of Biological Chemistry 272 (6), 3346-3354, 1997 | 734 | 1997 |
| Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart AP Halestrap, PM Kerr, S Javadov, KY Woodfield Biochimica et Biophysica Acta (BBA)-Bioenergetics 1366 (1-2), 79-94, 1998 | 712 | 1998 |
| Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts EJ Griffiths, AP Halestrap Journal of molecular and cellular cardiology 25 (12), 1461-1469, 1993 | 702 | 1993 |
| Calcium, mitochondria and reperfusion injury: a pore way to die AP Halestrap Biochemical Society Transactions 34 (2), 232-237, 2006 | 689 | 2006 |
Saadeh SuleimanUniversity of BristolVerified email at bristol.ac.uk
