Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine FW Pun, GHD Leung, HW Leung, BHM Liu, X Long, IV Ozerov, J Wang, ... Aging (Albany NY) 14 (6), 2475, 2022 | 42 | 2022 |
Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics–An AI-Enabled Biological Target Discovery Platform FW Pun, BHM Liu, X Long, HW Leung, GHD Leung, QT Mewborne, J Gao, ... Frontiers in Aging Neuroscience, 638, 2022 | 35 | 2022 |
Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery A Urban, D Sidorenko, D Zagirova, E Kozlova, A Kalashnikov, S Pushkov, ... Aging (Albany NY) 15 (11), 4649, 2023 | 6 | 2023 |
A comprehensive AI‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging FW Pun, GHD Leung, HW Leung, J Rice, T Schmauck‐Medina, S Lautrup, ... Aging Cell, e14017, 2023 | 5 | 2023 |
Pten Regulates Cardiomyocyte Differentiation by Modulating Non‐CG Methylation via Dnmt3 W Wang, G Lu, HB Liu, Z Xiong, HD Leung, R Cao, ALY Pang, X Su, ... Advanced Science 8 (17), 2100849, 2021 | 5 | 2021 |
Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics-an AI-enabled biological target discovery platform A Olsen, Z Harpaz, C Ren, A Shneyderman, A Veviorskiy, M Dralkina, ... Aging (Albany NY) 15 (8), 2863, 2023 | 3 | 2023 |
Biomedical generative pre-trained based transformer language model for age-related disease target discovery D Zagirova, S Pushkov, GHD Leung, BHM Liu, A Urban, D Sidorenko, ... Aging (Albany NY) 15 (18), 9293, 2023 | 2 | 2023 |
Leveraging AI to identify dual-purpose aging and disease targets GHD Leung, CW Wong, FW Pun, A Aliper, F Ren, A Zhavoronkov Expert Opinion on Therapeutic Targets, 1-4, 2023 | | 2023 |
Positive and Negative Impact of RNA Pol II Transcription on DNA Replication Progression P Rojas, J Wang, G Guglielmi, MM Sadurnì, L Pavlou, H Leung, F Spill, ... Available at SSRN 3827411, 2021 | | 2021 |