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Lorenz Bastian
Lorenz Bastian
Senior Clinician Scientist, University Medical Center Schleswig-Holstein, Kiel, Germany
Verified email at uksh.de
Title
Cited by
Cited by
Year
High VLA-4 expression is associated with adverse outcome and distinct gene expression changes in childhood B-cell precursor acute lymphoblastic leukemia at first relapse
S Shalapour, J Hof, R Kirschner-Schwabe, L Bastian, C Eckert, J Prada, ...
Haematologica 96 (11), 1627, 2011
842011
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia
L Bastian, MP Schroeder, C Eckert, C Schlee, JO Tanchez, S Kämpf, ...
Leukemia 33 (8), 1895-1909, 2019
542019
Synergistic activity of bortezomib and HDACi in preclinical models of B-cell precursor acute lymphoblastic leukemia via modulation of p53, PI3K/AKT, and NF-κB
L Bastian, J Hof, M Pfau, I Fichtner, C Eckert, G Henze, J Prada, ...
Clinical Cancer Research 19 (6), 1445-1457, 2013
472013
Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia
AR James, MP Schroeder, M Neumann, L Bastian, C Eckert, N Gökbuget, ...
Journal of Hematology & Oncology 12 (1), 1-16, 2019
402019
Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures
MP Schroeder, L Bastian, C Eckert, N Gökbuget, AR James, JO Tanchez, ...
Scientific reports 9 (1), 4188, 2019
302019
Silencing of GATA3 defines a novel stem cell-like subgroup of ETP-ALL
L Fransecky, M Neumann, S Heesch, C Schlee, J Ortiz-Tanchez, S Heller, ...
Journal of Hematology & Oncology 9 (1), 1-12, 2016
272016
Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL
K Müller, F Vogiatzi, D Winterberg, T Rösner, L Lenk, L Bastian, ...
Blood, The Journal of the American Society of Hematology 140 (1), 45-57, 2022
252022
UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment
L Bastian, AM Hartmann, T Beder, S Hänzelmann, J Kässens, ...
Leukemia 36 (6), 1676-1680, 2022
162022
In vivo inducible reverse genetics in patients’ tumors to identify individual therapeutic targets
M Carlet, K Völse, J Vergalli, M Becker, T Herold, A Arner, D Senft, ...
Nature communications 12 (1), 5655, 2021
122021
The sequence of application of methotrexate and histone deacetylase inhibitors determines either a synergistic or an antagonistic response in childhood acute lymphoblastic …
L Bastian, HG Einsiedel, G Henze, K Seeger, S Shalapour
Leukemia 25 (2), 359-361, 2011
112011
Development of an Epstein–Barr virus‐associated lymphoproliferative disorder in a patient treated with azacitidine for chronic myelomonocytic leukaemia
T Menter, M Schlageter, L Bastian, R Haberthür, AE Rätz Bravo, ...
Hematological oncology 32 (1), 47-51, 2014
102014
The Gene Expression Classifier ALLCatchR Identifies B-cell Precursor ALL Subtypes and Underlying Developmental Trajectories Across Age
T Beder, BT Hansen, AM Hartmann, J Zimmermann, E Amelunxen, ...
HemaSphere 7 (9), e939, 2023
8*2023
Irf4 deficiency vulnerates b-cell progeny for leukemogenesis via somatically acquired jak3 mutations conferring il-7 hypersensitivity
D Das Gupta, C Paul, N Samel, M Bieringer, D Staudenraus, F Marini, ...
Cell Death & Differentiation 29 (11), 2163-2176, 2022
82022
Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab
N Baumann, C Arndt, J Petersen, M Lustig, T Rösner, K Klausz, C Kellner, ...
Frontiers in Immunology 13, 949140, 2022
72022
Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells
M Lustig, C Chan, JH Jansen, M Bräutigam, MA Kölling, CL Gehlert, ...
Frontiers in Immunology 14, 1178817, 2023
62023
Inhibiting casein kinase 2 sensitizes acute lymphoblastic leukemia cells to venetoclax via MCL1 degradation
J Lázaro-Navarro, HJ Pimentel-Gutiérrez, A Gauert, AIH Hagemann, ...
Blood Advances 5 (24), 5501-5506, 2021
52021
Chemotherapy‐induced release of ADAM17 bearing EV as a potential resistance mechanism in ovarian cancer
G Hugendieck, M Lettau, S Andreas, S Neumann, N Reinhardt, P Arnold, ...
Journal of Extracellular Vesicles 12 (7), 12338, 2023
42023
Somatic TP53 mutations are preleukemic events in acute lymphoblastic leukemia
G Chitadze, A Stengel, C John-Klaua, J Bruckmüller, H Trautmann, ...
Blood 141 (13), 1640-1644, 2023
42023
IGH rearrangement evolution in adult KMT2A-rearranged B-cell precursor ALL: implications for cell-of-origin and MRD monitoring
F Darzentas, M Szczepanowski, M Kotrová, M Kelm, A Hartmann, T Beder, ...
Hemasphere 7 (1), e820, 2023
42023
Molecular subgroups of T cell acute lymphoblastic leukemia in adults treated according to GMALL protocols
M Neumann, L Bastian, S Hänzelmann, A Hartmann, H Trautmann, ...
Blood 136, 37-38, 2020
42020
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