| St John's wort increases expression of P‐glycoprotein: implications for drug interactions M Hennessy, D Kelleher, JP Spiers, M Barry, P Kavanagh, D Back, ... British journal of clinical pharmacology 53 (1), 75-82, 2002 | 360 | 2002 |
| A primer on the mechanics of P-glycoprotein the multidrug transporter M Hennessy, JP Spiers Pharmacological research 55 (1), 1-15, 2007 | 289 | 2007 |
| Collagen type-I degradation is related to arterial stiffness in hypertensive and normotensive subjects M McNulty, A Mahmud, P Spiers, J Feely Journal of human hypertension 20 (11), 867-873, 2006 | 125 | 2006 |
| Matrix metalloproteinase-9 polymorphism contributes to blood pressure and arterial stiffness in essential hypertension S Zhou, J Feely, JP Spiers, A Mahmud Journal of human hypertension 21 (11), 861-867, 2007 | 93 | 2007 |
| Nuclear receptor-mediated induction of CYP450 by antiretrovirals: functional consequences of NR1I2 (PXR) polymorphisms and differential prevalence in whites and sub-Saharan … J Svaard, JP Spiers, F Mulcahy, M Hennessy JAIDS Journal of Acquired Immune Deficiency Syndromes 55 (5), 536-549, 2010 | 92 | 2010 |
| Aging is associated with increased matrix metalloproteinase-2 activity in the human aorta M McNulty, P Spiers, E McGovern, J Feely American journal of hypertension 18 (4), 504-509, 2005 | 90 | 2005 |
| Time and frequency domain assessment of heart rate variability: a theoretical and clinical appreciation JP Spiers, B Silke, U McDermott, RG Shanks, DWG Harron Clinical Autonomic Research 3, 145-158, 1993 | 75 | 1993 |
| Activation of immune and inflammatory systems in chronic heart failure: novel therapeutic approaches KZ Gong, G Song, JP Spiers, EJ Kelso, ZG Zhang International journal of clinical practice 61 (4), 611-621, 2007 | 63 | 2007 |
| Alterations in vascular matrix metalloproteinase due to ageing and chronic hypertension: effects of endothelin receptor blockade JP Spiers, EJ Kelso, WF Siah, G Edge, G Song, BJ McDermott, ... Journal of hypertension 23 (9), 1717-1724, 2005 | 59 | 2005 |
| Long-term statin therapy in patients with systolic heart failure and normal cholesterol: effects on elevated serum markers of collagen turnover, inflammation, and B-type … E Abulhul, K McDonald, R Martos, D Phelan, JP Spiers, M Hennessy, ... Clinical therapeutics 34 (1), 91-100, 2012 | 51 | 2012 |
| Regulation of the phosphoprotein phosphatase 2A system and its modulation during oxidative stress: A potential therapeutic target? IS Elgenaidi, JP Spiers Pharmacology & therapeutics 198, 68-89, 2019 | 50 | 2019 |
| Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients M Hennessy, S Clarke, JP Spiers, D Kelleher, F Mulcahy, P Hoggard, ... Antiviral therapy 9 (1), 115-122, 2004 | 43 | 2004 |
| EndothelinA receptor subtype mediates endothelin-induced contractility in left ventricular cardiomyocytes isolated from rabbit myocardium EJ Kelso, BJ McDermott, B Silke, JP Spiers Journal of Pharmacology and Experimental Therapeutics 294 (3), 1047-1052, 2000 | 42 | 2000 |
| Evaluation of non-invasive blood pressure measurement by the Finapres method at rest and during dynamic exercise in subjects with cardiovascular insufficiency B Silke, JP Spiers, S Boyd, E Graham, G McParland, ME Scott Clinical Autonomic Research 4, 49-56, 1994 | 42 | 1994 |
| The relationship between the MMP system, adrenoceptors and phosphoprotein phosphatases A Rietz, JP Spiers British journal of pharmacology 166 (4), 1225-1243, 2012 | 40 | 2012 |
| Protection of cardiomyocyte function by propofol during simulated ischemia is associated with a direct action to reduce pro-oxidant activity BJ McDermott, S McWilliams, K Smyth, EJ Kelso, JP Spiers, YY Zhao, ... Journal of molecular and cellular cardiology 42 (3), 600-608, 2007 | 36 | 2007 |
| Dual effects of endothelin-1 on the L-type Ca2+ current in ventricular cardiomyocytes E Kelso, P Spiers, B McDermott, N Scholfield, B Silke European journal of pharmacology 308 (3), 351-355, 1996 | 31 | 1996 |
| Protein phosphatase 2A regulation of markers of extracellular matrix remodelling in hepatocellular carcinoma cells: functional consequences for tumour invasion MP Ward, JP Spiers British journal of pharmacology 174 (10), 1116-1130, 2017 | 26 | 2017 |
| Intracellular indinavir pharmacokinetics in HIV-infected patients: comparison with plasma pharmacokinetics M Hennessy, S Clarke, JP Spiers, F Mulcahy, D Kelleher, E Meadon, ... Antiviral therapy 8 (3), 191-198, 2003 | 26 | 2003 |
| Neuropeptide Y Y1 receptor regulates protein turnover and constitutive gene expression in hypertrophying cardiomyocytes SM Nicholl, D Bell, JP Spiers, BJ McDermott European journal of pharmacology 441 (1-2), 23-34, 2002 | 26 | 2002 |
Martina Hennessyassociate professor Medical education Trinity College DublinVerified email at tcd.ie
