Disturbed flow increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, inducing aortic valve calcification by the pVHL (von Hippel-Lindau Protein) and HIF-1α (Hypoxia … J Fernandez Esmerats, N Villa-Roel, S Kumar, L Gu, MT Salim, M Ohh, ... Arteriosclerosis, thrombosis, and vascular biology 39 (3), 467-481, 2019 | 64 | 2019 |
Shear-sensitive genes in aortic valve endothelium J Fernández Esmerats, J Heath, H Jo Antioxidants & redox signaling 25 (7), 401-414, 2016 | 53 | 2016 |
Identification of side-and shear-dependent microRNAs regulating porcine aortic valve pathogenesis S Rathan, CJ Ankeny, S Arjunon, Z Ferdous, S Kumar, ... Scientific reports 6 (1), 25397, 2016 | 51 | 2016 |
Mechanosensitive microRNA-181b regulates aortic valve endothelial matrix degradation by targeting TIMP3 JM Heath, J Fernandez Esmerats, L Khambouneheuang, S Kumar, ... Cardiovascular engineering and technology 9, 141-150, 2018 | 49 | 2018 |
Suture forces in undersized mitral annuloplasty: novel device and measurements AW Siefert, EL Pierce, M Lee, MØ Jensen, C Aoki, S Takebayashi, ... The Annals of thoracic surgery 98 (1), 305-309, 2014 | 24 | 2014 |
Hypoxia inducible factor 1α inhibitor PX-478 reduces atherosclerosis in mice N Villa-Roel, K Ryu, L Gu, JF Esmerats, DW Kang, S Kumar, H Jo Atherosclerosis 344, 20-30, 2022 | 17 | 2022 |
miR-214 is stretch-sensitive in aortic valve and inhibits aortic valve calcification MT Salim, JF Esmerats, S Arjunon, N Villa-Roel, RM Nerem, H Jo, ... Annals of biomedical engineering 47, 1106-1115, 2019 | 15 | 2019 |
Hemodynamics and mechanobiology of aortic valve calcification JF Esmerats, J Heath, A Rezvan, H Jo Biomedical Engineering: Frontier Research and Converging Technologies, 237-261, 2016 | 2 | 2016 |
Hypoxia Inducible Factor-1α Inhibitor, PX-478, Reduces Atherosclerosis in vivo N Villa-Roel, L Gu, J Fernandez Esmerats, DW Kang, S Kumar, H Jo Arteriosclerosis, Thrombosis, and Vascular Biology 40 (Suppl_1), A366-A366, 2020 | 1 | 2020 |
Shear-Sensitive miRNA-181b Impairs Anti-Inflammatory Signaling in the Aortic Valve Endothelium J Heath, JF Esmerats, R Simmons, S Kumar, H Jo Cardiology 134 (2), 167-167, 2016 | 1 | 2016 |
Role of miRNA-483-3p in Valvular Endothelial Dysfunction JF Esmerats, J Heath, S Kumar, H Jo Cardiology 134 (2), 178-178, 2016 | 1 | 2016 |
Methods and Compositions for Managing Vascular Conditions Using miR-483 Mimics and HIF1alpha Pathway Inhibitors H Jo, JF ESMERATS, N Villa-Roel US Patent App. 17/544,801, 2022 | | 2022 |
Methods and compositions for managing vascular conditions using miR-483 mimics and HIF1alpha pathway inhibitors H Jo, JF ESMERATS, N Villa-Roel US Patent 11,225,660, 2022 | | 2022 |
Disturbed flow increases UBE2C via loss of miR-483-3p, inducing aortic valve calcification by the HIF1α pathway in endothelial cells JF Esmerats, N Villa-Roel, S Kumar, L Gu, MT Salim, M Ohh, WR Taylor, ... Arteriosclerosis, thrombosis, and vascular biology 39 (3), 467, 2019 | | 2019 |
Shear-Dependent Aortic Valve Endothelial Inflammation and Calcification Are Regulated by O-GlcNAc Modification of MEF2C Transcription Factor J Heath, H Kim, J Fernandez Esmerats, R Simmons, S Kumar, J Cho, H Jo Circulation 134 (suppl_1), A19733-A19733, 2016 | | 2016 |