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Luke H. Chao
Luke H. Chao
Assistant Professor, Harvard Medical School
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680
MA Young, NP Shah, LH Chao, M Seeliger, ZV Milanov, WH Biggs III, ...
Cancer research 66 (2), 1007-1014, 2006
3502006
A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin-dependent kinase II holoenzyme
LH Chao, MM Stratton, IH Lee, OS Rosenberg, J Levitz, DJ Mandell, ...
Cell 146 (5), 732-745, 2011
2792011
Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation
LH Chao, P Pellicena, S Deindl, LA Barclay, H Schulman, J Kuriyan
Nature structural & molecular biology 17 (3), 264-272, 2010
1372010
Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane
Y Ge, X Shi, S Boopathy, J McDonald, AW Smith, LH Chao
elife 9, e50973, 2020
1312020
Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity
M Stratton, IH Lee, M Bhattacharyya, SM Christensen, LH Chao, ...
Elife 3, e01610, 2014
1162014
Structural studies on the regulation of Ca2+/calmodulin dependent protein kinase II
MM Stratton, LH Chao, H Schulman, J Kuriyan
Current opinion in structural biology 23 (2), 292-301, 2013
1022013
Sequential conformational rearrangements in flavivirus membrane fusion
LH Chao, DE Klein, AG Schmidt, JM Peña, SC Harrison
Elife 3, e04389, 2014
922014
Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site
CM Nunn, M Jeeves, MJ Cliff, GT Urquhart, RR George, LH Chao, ...
Journal of molecular biology 350 (1), 145-155, 2005
822005
NNT mediates redox-dependent pigmentation via a UVB-and MITF-independent mechanism
J Allouche, I Rachmin, K Adhikari, LM Pardo, JH Lee, AM McConnell, ...
Cell 184 (16), 4268-4283. e20, 2021
422021
Identification and characterization of a novel broad-spectrum virus entry inhibitor
Y Chou, C Cuevas, M Carocci, SH Stubbs, M Ma, DK Cureton, L Chao, ...
Journal of virology 90 (9), 4494-4510, 2016
372016
Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation
R Sloutsky, N Dziedzic, MJ Dunn, RM Bates, AP Torres-Ocampo, ...
Science signaling 13 (641), eaaz0240, 2020
332020
Cell wall synthesis and remodelling dynamics determine division site architecture and cell shape in Escherichia coli
PP Navarro, A Vettiger, VY Ananda, PM Llopis, C Allolio, TG Bernhardt, ...
Nature Microbiology 7 (10), 1621-1634, 2022
322022
The tarantula toxin GxTx detains K+ channel gating charges in their resting conformation
DC Tilley, JM Angueyra, KS Eum, H Kim, LH Chao, AW Peng, JT Sack
Journal of General Physiology 151 (3), 292-315, 2019
312019
Cryo-EM insight into the structure of MTOR complex 1 and its interactions with Rheb and substrates
LH Chao, J Avruch
F1000Research 8, 2019
232019
How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion
LH Chao, J Jang, A Johnson, A Nguyen, NS Gray, PL Yang, SC Harrison
Elife 7, e36461, 2018
232018
Absence of cardiolipin from the outer leaflet of a mitochondrial inner membrane mimic restricts Opa1-mediated fusion
Y Ge, S Boopathy, TH Nguyen, CM Lugo, LH Chao
Frontiers in Molecular Biosciences 8, 769135, 2021
92021
Correction: Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activity
M Stratton, IH Lee, M Bhattacharyya, SM Christensen, LH Chao, ...
Elife 3, e02490, 2014
92014
In situ architecture of Opa1-dependent mitochondrial cristae remodeling
MY Fry, PP Navarro, P Hakim, VY Ananda, X Qin, JC Landoni, S Rath, ...
The EMBO Journal 43 (3), 391-413, 2024
62024
Cell wall synthesis and remodeling dynamics determine bacterial division site architecture and cell shape
PP Navarro, A Vettiger, VY Ananda, PM Llopis, C Allolio, TG Bernhardt, ...
bioRxiv, 2021.10. 02.462887, 2021
42021
A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of Trichomonas vaginalis
EN Abdulaziz, TA Bell, B Rashid, ML Heacock, T Begic, OS Skinner, ...
Journal of Biological Chemistry 298 (8), 2022
32022
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