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Laszlo Petri
Laszlo Petri
Research Centre for Natural Sciences
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A road map for prioritizing warheads for cysteine targeting covalent inhibitors
P Abranyi-Balogh, L Petri, T Imre, P Szijj, A Scarpino, M Hrast, A Mitrović, ...
European journal of medicinal chemistry 160, 94-107, 2018
1112018
Covalent fragment libraries in drug discovery
A Keeley, L Petri, P Ábrányi-Balogh, GM Keserű
Drug Discovery Today 25 (6), 983-996, 2020
842020
An electrophilic warhead library for mapping the reactivity and accessibility of tractable cysteines in protein kinases
L Petri, A Egyed, D Bajusz, T Imre, A Hetényi, T Martinek, ...
European Journal of Medicinal Chemistry 207, 112836, 2020
322020
Comparative reactivity analysis of small-molecule thiol surrogates
L Petri, P Ábrányi-Balogh, PR Varga, T Imre, GM Keserű
Bioorganic & Medicinal Chemistry 28 (7), 115357, 2020
312020
Cysteine specific bioconjugation with benzyl isothiocyanates
L Petri, PA Szijj, Á Kelemen, T Imre, Á Gömöry, MTW Lee, K Hegedűs, ...
RSC advances 10 (25), 14928-14936, 2020
282020
WIDOCK: a reactive docking protocol for virtual screening of covalent inhibitors
A Scarpino, L Petri, D Knez, T Imre, P Ábrányi-Balogh, GG Ferenczy, ...
Journal of Computer-Aided Molecular Design 35, 223-244, 2021
252021
Assessment of tractable cysteines for covalent targeting by screening covalent fragments
L Petri, P Ábrányi‐Balogh, I Tímea, G Pálfy, A Perczel, D Knez, M Hrast, ...
ChemBioChem 22 (4), 743-753, 2021
172021
Bromo-Cyclobutenaminones as New Covalent UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) Inhibitors
DJ Hamilton, P Ábrányi-Balogh, A Keeley, L Petri, M Hrast, T Imre, ...
Pharmaceuticals 13 (11), 362, 2020
122020
A covalent strategy to target intrinsically disordered proteins: discovery of novel tau aggregation inhibitors
L Petri, P Ábrányi-Balogh, D Vagrys, T Imre, N Varró, I Mándity, A Rácz, ...
European Journal of Medicinal Chemistry 231, 114163, 2022
102022
Discovery of selective fragment-sized immunoproteasome inhibitors
L Kollár, M Gobec, B Szilágyi, M Proj, D Knez, P Ábrányi-Balogh, L Petri, ...
European Journal of Medicinal Chemistry 219, 113455, 2021
102021
Prospective evaluation of spent sulfuric acid recovery by process simulation
K Várnai, L Petri, L Nagy
Periodica Polytechnica Chemical Engineering 65 (2), 243-250, 2021
82021
Semisynthetic teicoplanin derivatives with dual antimicrobial activity against SARS-CoV-2 and multiresistant bacteria
I Bereczki, V Vimberg, E Lőrincz, H Papp, L Nagy, S Kéki, G Batta, ...
Scientific reports 12 (1), 16001, 2022
72022
Synthesis of New Chiral Crown Ethers Containing Phosphine or Secondary Phosphine Oxide Units
H Szabó-Szentjóbi, I Majoros, A Márton, I Leveles, BG Vértessy, ...
Synthesis 52 (19), 2870-2882, 2020
72020
Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead
K Grabrijan, M Hrast, M Proj, A Dolšak, I Zdovc, T Imre, L Petri, ...
European journal of medicinal chemistry 243, 114752, 2022
62022
Fragment-sized and bidentate (Immuno) proteasome inhibitors derived from cysteine and threonine targeting warheads
L Kollár, M Gobec, M Proj, L Smrdel, D Knez, T Imre, Á Gömöry, L Petri, ...
Cells 10 (12), 3431, 2021
52021
Activation-free sulfonyl fluoride probes for fragment screening
L Petri, P Ábrányi-Balogh, N Csorba, A Keeley, J Simon, I Ranđelović, ...
Molecules 28 (7), 3042, 2023
42023
Next-generation heterocyclic electrophiles as small-molecule covalent MurA inhibitors
P Ábrányi-Balogh, A Keeley, GG Ferenczy, L Petri, T Imre, K Grabrijan, ...
Pharmaceuticals 15 (12), 1484, 2022
32022
Synthesis of achiral and new chiral crown ethers containing a triphenylphosphane unit
T Szabó, L Petri, S Gergely, P Huszthy
Ann Arbor, MI: Michigan Publishing, University of Michigan Library, 2015
32015
Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors
AB Keeley, A Kopranovic, V Di Lorenzo, P Ábrányi-Balogh, N Jänsch, ...
Journal of Medicinal Chemistry 67 (1), 572-585, 2023
22023
Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency
Z Orgován, N Péczka, L Petri, P Ábrányi-Balogh, I Ranđelović, S Tóth, ...
European Journal of Medicinal Chemistry 250, 115212, 2023
22023
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