The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells LP Vu, BF Pickering, Y Cheng, S Zaccara, D Nguyen, G Minuesa, T Chou, ... Nature medicine 23 (11), 1369, 2017 | 1029 | 2017 |
m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment Y Cheng, H Luo, F Izzo, BF Pickering, D Nguyen, R Myers, A Schurer, ... Cell Reports 28 (7), 1703-1716. e6, 2019 | 137 | 2019 |
The chromatin remodelling factor ATRX suppresses R‐loops in transcribed telomeric repeats DTT Nguyen, HPJ Voon, B Xella, C Scott, D Clynes, C Babbs, H Ayyub, ... EMBO reports 18 (6), 914-928, 2017 | 126 | 2017 |
N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation Y Cheng, W Xie, BF Pickering, KL Chu, AM Savino, X Yang, H Luo, ... Cancer Cell, 2021 | 125 | 2021 |
MicroRNA-125b transforms myeloid cell lines by repressing multiple mRNA M Bousquet, D Nguyen, C Chen, L Shields, HF Lodish Haematologica 97 (11), 1713-1721, 2012 | 83 | 2012 |
HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells DTT Nguyen, Y Lu, KL Chu, X Yang, SM Park, ZN Choo, CR Chin, ... Nature Communications 11 (1), 1-12, 2020 | 41 | 2020 |
Transcriptional control of CBX5 by the RNA-binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia C Prieto, DTT Nguyen, Z Liu, J Wheat, A Perez, S Gourkanti, T Chou, ... Nature Cancer, 1-17, 2021 | 16 | 2021 |
BTG1 mutation yields supercompetitive B cells primed for malignant transformation C Mlynarczyk, M Teater, J Pae, CR Chin, L Wang, T Arulraj, D Barisic, ... Science 379 (6629), eabj7412, 2023 | 13 | 2023 |
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells F Herrejon Chavez, H Luo, P Cifani, A Pine, KL Chu, S Joshi, E Barin, ... Nature Communications 14 (1), 2290, 2023 | 2 | 2023 |
RNA Binding Protein Rbmx Is Required in Acute Myeloid Leukemia By Regulating the Transcriptional Activity of the Heterochromatin Protein HP1α C Prieto, D Nguyen, LP Vu, A Perez, S Gourkanti, A Schurer, T Chou, ... Blood 132 (Suppl 1), 883-883, 2018 | 2 | 2018 |
BTG1 Mutation Promotes Aggressive Lymphoma Development By Lowering the Threshold to MYC Activation and Generating "Super-Competitor" B Cells Blood 138 ((Supplement 1): 359), 2021 | 1 | 2021 |
The RNA Binding Protein MSI2 Has Increased RNA Binding Activity in Leukemic Stem Cells Compared to Normal Hematopoietic Stem Cells D Nguyen, Y Lu, Z Choo, C Chin, C Prieto, S Gourkanti, C Leslie, ... Blood 132 (Suppl 1), 884-884, 2018 | 1 | 2018 |
The 2022 generation M Barry-Hundeyin, J Carrot-Zhang, T Dayton, S Ghazanfar, LM Guenther, ... Nature Cancer 3 (12), 1426-1431, 2022 | | 2022 |
Abstract A24: BTG1 mutations confer a fitness advantage and promote aggressive B cell lymphoma development by lowering the threshold for MYC induction C Mlynarczyk, M Teater, J Pae, L Wang, J Ersching, A Papin, D Barisic, ... Blood Cancer Discovery 3 (5_Supplement), A24-A24, 2022 | | 2022 |
RNA Binding Protein Syncrip Is Required for the Low-Output HSC By Sustaining Proteome Quality LPV Florisela Herrejon Chavez, Paolo Cifani, Alli Pine, Karen L Chu, Ersilia ... Blood 138 (Supplement 1: 296), 2021 | | 2021 |
2007–TRANSCRIPTIONAL CONTROL OF CBX5 BY THE RNA BINDING PROTEINS RBMX AND RBMXL1 MAINTAINS CHROMATIN STATE IN MYELOID LEUKEMIA D Nguyen, C Prieto, Z Liu, J Wheat, A Perez, S Gourkanti, T Chou, E Barin, ... Experimental Hematology 100, S30-S31, 2021 | | 2021 |
Transcriptional Control of HP1a By the RNA Binding Proteins Rbmx/L1 Maintain Chromatin State in Myeloid Leukemia Blood 136 ((Supplement 1): 15), 2020 | | 2020 |
m6a Regulates Differentiation State and mRNA Translation in Myeloid Leukemia LP Vu, BF Pickering, Y Cheng, Z Sara, D Nguyen, G Minuesa, T Chou, ... Blood 130 (Suppl 1), 791-791, 2017 | | 2017 |
Targeting of the chromatin remodeler ATRX to G-rich regions is transcription- dependent and correlates with R-loop formation DTTN Hsiao Phin J Voon, Barbara Xella, Caroline Scott, David Clynes ... DNA repair and Genome Instability in a Chromatin environment conference, 2015 | | 2015 |
How does the chromatin remodeler ATRX identify its targets in the genome? DTT Nguyen University of Oxford, 2014 | | 2014 |