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Joshua T. Mattila
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Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms
JT Mattila, OO Ojo, D Kepka-Lenhart, S Marino, JH Kim, SY Eum, LE Via, ...
The Journal of Immunology 191 (2), 773-784, 2013
3692013
Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology
JM Cicchese, S Evans, C Hult, LR Joslyn, T Wessler, JA Millar, S Marino, ...
Immunological reviews 285 (1), 147-167, 2018
2202018
Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection
S Marino, NA Cilfone, JT Mattila, JJ Linderman, JAL Flynn, DE Kirschner
Infection and immunity 83 (1), 324-338, 2015
1992015
Reactivation of latent tuberculosis in cynomolgus macaques infected with SIV is associated with early peripheral T cell depletion and not virus load
CR Diedrich, JT Mattila, E Klein, C Janssen, J Phuah, TJ Sturgeon, ...
PloS one 5 (3), e9611, 2010
1982010
“Of mice and men”: arginine metabolism in macrophages
AC Thomas, JT Mattila
Frontiers in immunology 5, 112253, 2014
1922014
Immunology studies in non‐human primate models of tuberculosis
JAL Flynn, HP Gideon, JT Mattila, PL Lin
Immunological reviews 264 (1), 60-73, 2015
1752015
Activated B cells in the granulomas of nonhuman primates infected with Mycobacterium tuberculosis
JY Phuah, JT Mattila, PL Lin, JAL Flynn
The American journal of pathology 181 (2), 508-514, 2012
1622012
Nitric oxide synthase: non-canonical expression patterns
JT Mattila, AC Thomas
Frontiers in immunology 5, 112313, 2014
1552014
CD4+ Regulatory T Cells in a Cynomolgus Macaque Model of Mycobacterium tuberculosis Infection
AM Green, JT Mattila, CL Bigbee, KS Bongers, P Ling Lin, JAL Flynn
The Journal of infectious diseases 202 (4), 533-541, 2010
1142010
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control
HP Gideon, TK Hughes, CN Tzouanas, MH Wadsworth, AA Tu, ...
Immunity 55 (5), 827-846. e10, 2022
1002022
Neutrophils express pro-and anti-inflammatory cytokines in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques
HP Gideon, J Phuah, BA Junecko, JT Mattila
Mucosal immunology 12 (6), 1370-1381, 2019
982019
Simian immunodeficiency virus-induced changes in T cell cytokine responses in cynomolgus macaques with latent Mycobacterium tuberculosis infection are associated with timing of …
JT Mattila, CR Diedrich, PL Lin, J Phuah, JAL Flynn
The Journal of Immunology 186 (6), 3527-3537, 2011
902011
Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques
SKC Ganchua, AM Cadena, P Maiello, HP Gideon, AJ Myers, BF Junecko, ...
PLoS pathogens 14 (11), e1007337, 2018
812018
Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity–mediated antimicrobial responses with caseation during Mycobacterium …
NA Cilfone, CB Ford, S Marino, JT Mattila, HP Gideon, JAL Flynn, ...
The Journal of Immunology 194 (2), 664-677, 2015
732015
Isolation of Cell Lines and a Rickettsial Endosymbiont from the Soft Tick Carios capensis (Acari: Argasidae: Ornithodorinae)
JT Mattila, NY Burkhardt, HJ Hutcheson, UG Munderloh, TJ Kurtti
Journal of medical entomology 44 (6), 1091-1101, 2007
712007
A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment
E Pienaar, NA Cilfone, PL Lin, V Dartois, JT Mattila, JR Butler, JAL Flynn, ...
Journal of theoretical biology 367, 166-179, 2015
702015
Active transforming growth factor-β is associated with phenotypic changes in granulomas after drug treatment in pulmonary tuberculosis
RM DiFazio, JT Mattila, EC Klein, LR Cirrincione, M Howard, EA Wong, ...
Fibrogenesis & tissue repair 9, 1-11, 2016
652016
Granzyme B‐expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis‐infected cynomolgus macaques
JT Mattila, P Maiello, T Sun, LE Via, JAL Flynn
Cellular microbiology 17 (8), 1085-1097, 2015
652015
Predicting lymph node output efficiency using systems biology
C Gong, JT Mattila, M Miller, JAL Flynn, JJ Linderman, D Kirschner
Journal of theoretical biology 335, 169-184, 2013
582013
IL-10 impairs local immune response in lung granulomas and lymph nodes during early Mycobacterium tuberculosis infection
EA Wong, S Evans, CR Kraus, KD Engelman, P Maiello, WJ Flores, ...
The Journal of Immunology 204 (3), 644-659, 2020
522020
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Articles 1–20