| Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice T Wyss-Coray, F Yan, AHT Lin, JD Lambris, JJ Alexander, RJ Quigg, ... Proceedings of the National Academy of Sciences 99 (16), 10837-10842, 2002 | 551 | 2002 |
| New approaches to the treatment of dense deposit disease RJH Smith, J Alexander, PN Barlow, M Botto, TL Cassavant, HT Cook, ... Journal of the American Society of Nephrology 18 (9), 2447-2456, 2007 | 332 | 2007 |
| Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial J He, R Zhang, M Shao, X Zhao, M Miao, J Chen, J Liu, X Zhang, X Zhang, ... Annals of the rheumatic diseases 79 (1), 141-149, 2020 | 262 | 2020 |
| TNF is a key mediator of septic encephalopathy acting through its receptor, TNF receptor-1 JJ Alexander, A Jacob, P Cunningham, L Hensley, RJ Quigg Neurochemistry international 52 (3), 447-456, 2008 | 257 | 2008 |
| Ammonia induces the mitochondrial permeability transition in primary cultures of rat astrocytes G Bai, KV Rama Rao, CRK Murthy, KS Panickar, AR Jayakumar, ... Journal of neuroscience research 66 (5), 981-991, 2001 | 215 | 2001 |
| The complement cascade: Yin–Yang in neuroinflammation–neuro‐protection and‐degeneration JJ Alexander, AJ Anderson, SR Barnum, B Stevens, AJ Tenner Journal of neurochemistry 107 (5), 1169-1187, 2008 | 208 | 2008 |
| Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes P Park, M Haas, PN Cunningham, L Bao, JJ Alexander, RJ Quigg American Journal of Physiology-Renal Physiology 282 (2), F352-F357, 2002 | 163 | 2002 |
| Pathogenesis of septic encephalopathy P Pytel, JJ Alexander Current opinion in neurology 22 (3), 283-287, 2009 | 161 | 2009 |
| Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy RA Hawkins, J Jessy, AM Mans, MR De Joseph Journal of neurochemistry 60 (3), 1000-1006, 1993 | 138 | 1993 |
| C5a alters blood-brain barrier integrity in experimental lupus A Jacob, B Hack, E Chiang, JGN Garcia, RJ Quigg, JJ Alexander The FASEB Journal 24 (6), 1682, 2010 | 126 | 2010 |
| Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury RJ Quigg, C He, A Lim, D Berthiaume, JJ Alexander, D Kraus, ... The Journal of experimental medicine 188 (7), 1321-1331, 1998 | 122 | 1998 |
| Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice L Bao, M Haas, SA Boackle, DM Kraus, PN Cunningham, P Park, ... The Journal of Immunology 168 (7), 3601-3607, 2002 | 121 | 2002 |
| Immune complex glomerulonephritis in C4-and C3-deficient mice RJ Quigg, A Lim, M Haas, JJ Alexander, C He, MC Carroll Kidney international 53 (2), 320-330, 1998 | 110 | 1998 |
| Hyperammonaemia does not impair brain function in the absence of net glutamine synthesis RA Hawkins, J Jessy Biochemical Journal 277 (3), 697-703, 1991 | 107 | 1991 |
| Septic encephalopathy: inflammation in man and mouse A Jacob, JR Brorson, JJ Alexander Neurochemistry international 58 (4), 472-476, 2011 | 99 | 2011 |
| Factor H uptake regulates intracellular C3 activation during apoptosis and decreases the inflammatory potential of nucleosomes M Martin, J Leffler, KI Smoląg, J Mytych, A Björk, LD Chaves, JJ Alexander, ... Cell Death & Differentiation 23 (5), 903-911, 2016 | 96 | 2016 |
| Altered vitamin D metabolism in type II diabetic mouse glomeruli may provide protection from diabetic nephropathy Y Wang, J Zhou, AW Minto, BK Hack, JJ Alexander, M Haas, YC Li, ... Kidney international 70 (5), 882-891, 2006 | 95 | 2006 |
| Administration of the soluble complement inhibitor, Crry-Ig, reduces inflammation and aquaporin 4 expression in lupus cerebritis JJ Alexander, L Bao, A Jacob, DM Kraus, VM Holers, RJ Quigg Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1639 (3), 169-176, 2003 | 94 | 2003 |
| Neomycin reduces the intestinal production of ammonia from glutamine RA Hawkins, J Jessy, AM Mans, A Chedid, MR DeJoseph Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity, 125-134, 1994 | 90 | 1994 |
| Blood-brain barrier (BBB) and the complement landscape JJ Alexander Molecular immunology 102, 26-31, 2018 | 85 | 2018 |
Richard QuiggUniversity at Buffalo; University of ChicagoVerified email at uchicago.edu
