Cellular and molecular mechanisms of metformin: an overview B Viollet, B Guigas, NS Garcia, J Leclerc, M Foretz, F Andreelli Clinical science 122 (6), 253-270, 2012 | 2161 | 2012 |
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state M Foretz, S Hébrard, J Leclerc, E Zarrinpashneh, M Soty, G Mithieux, ... The Journal of clinical investigation 120 (7), 2355-2369, 2010 | 1438 | 2010 |
Knockout of the α2 but not α1 5′-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranosidebut not contraction-induced glucose uptake … SB Jørgensen, B Viollet, F Andreelli, C Frøsig, JB Birk, P Schjerling, ... Journal of Biological Chemistry 279 (2), 1070-1079, 2004 | 657 | 2004 |
Activation of AMP‐activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders B Viollet, M Foretz, B Guigas, S Horman, R Dentin, L Bertrand, L Hue, ... The Journal of physiology 574 (1), 41-53, 2006 | 650 | 2006 |
The AMP-activated protein kinase α2 catalytic subunit controls whole-body insulin sensitivity B Viollet, F Andreelli, SB Jørgensen, C Perrin, A Geloen, D Flamez, J Mu, ... The Journal of clinical investigation 111 (1), 91-98, 2003 | 617 | 2003 |
AMP‐activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives B Viollet, B Guigas, J Leclerc, S Hébrard, L Lantier, R Mounier, F Andreelli, ... Acta physiologica 196 (1), 81-98, 2009 | 565 | 2009 |
Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver M Foretz, N Ancellin, F Andreelli, Y Saintillan, P Grondin, A Kahn, ... Diabetes 54 (5), 1331-1339, 2005 | 509 | 2005 |
AMPK inhibition in health and disease B Viollet, S Horman, J Leclerc, L Lantier, M Foretz, M Billaud, S Giri, ... Critical reviews in biochemistry and molecular biology 45 (4), 276-295, 2010 | 481 | 2010 |
Increased uncoupling protein-2 and-3 mRNA expression during fasting in obese and lean humans. L Millet, H Vidal, F Andreelli, D Larrouy, JP Riou, D Ricquier, M Laville, ... The Journal of clinical investigation 100 (11), 2665-2670, 1997 | 443 | 1997 |
Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice S Troy, M Soty, L Ribeiro, L Laval, S Migrenne, X Fioramonti, B Pillot, ... Cell metabolism 8 (3), 201-211, 2008 | 409 | 2008 |
AMPK: Lessons from transgenic and knockout animals B Viollet, Y Athea, R Mounier, B Guigas, E Zarrinpashneh, S Horman, ... Frontiers in bioscience (Landmark edition) 14, 19, 2009 | 356 | 2009 |
Effects of α‐AMPK knockout on exercise‐induced gene activation in mouse skeletal muscle SB Jørgensen, JFP Wojtaszewski, B Viollet, F Andreelli, JB Birk, ... The FASEB journal 19 (9), 1146-1148, 2005 | 353 | 2005 |
Targeting the AMPK pathway for the treatment of Type 2 diabetes B Viollet, L Lantier, J Devin-Leclerc, S Hébrard, C Amouyal, R Mounier, ... Frontiers in bioscience (Landmark edition) 14, 3380, 2009 | 349 | 2009 |
Regulation by insulin of gene expression in human skeletal muscle and adipose tissue: evidence for specific defects in type 2 diabetes PH Ducluzeau, N Perretti, M Laville, F Andreelli, N Vega, JP Riou, H Vidal Diabetes 50 (5), 1134-1142, 2001 | 334 | 2001 |
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis S Vieira-Silva, G Falony, E Belda, T Nielsen, J Aron-Wisnewsky, ... Nature 581 (7808), 310-315, 2020 | 333 | 2020 |
The α2–5′ AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading SB Jørgensen, JN Nielsen, JB Birk, GS Olsen, B Viollet, F Andreelli, ... Diabetes 53 (12), 3074-3081, 2004 | 303 | 2004 |
Liver adenosine monophosphate-activated kinase-α2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin F Andreelli, M Foretz, C Knauf, PD Cani, C Perrin, MA Iglesias, B Pillot, ... Endocrinology 147 (5), 2432-2441, 2006 | 300 | 2006 |
Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models B Viollet, F Andreelli, SB Jørgensen, C Perrin, D Flamez, J Mu, ... Biochemical Society Transactions 31 (1), 216-219, 2003 | 286 | 2003 |
5-Aminoimidazole-4-Carboxamide-1-β-d-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase … B Guigas, L Bertrand, N Taleux, M Foretz, N Wiernsperger, D Vertommen, ... Diabetes 55 (4), 865-874, 2006 | 217 | 2006 |
Targeting AMP-activated protein kinase as a novel therapeutic approach for the treatment of metabolic disorders B Viollet, R Mounier, J Leclerc, A Yazigi, M Foretz, F Andreelli Diabetes & metabolism 33 (6), 395-402, 2007 | 204 | 2007 |