A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity SS Lee, RYN Lee, AG Fraser, RS Kamath, J Ahringer, G Ruvkun Nature genetics 33 (1), 40-48, 2003 | 1128 | 2003 |
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism SS Lee, S Kennedy, AC Tolonen, G Ruvkun science 300 (5619), 644-647, 2003 | 789 | 2003 |
p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans ER Troemel, SW Chu, V Reinke, SS Lee, FM Ausubel, DH Kim PLoS genetics 2 (11), e183, 2006 | 729 | 2006 |
A systematic RNAi screen for longevity genes in C. elegans B Hamilton, Y Dong, M Shindo, W Liu, I Odell, G Ruvkun, SS Lee Genes & development 19 (13), 1544-1555, 2005 | 640 | 2005 |
Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein SS Lee, RS Weiss, RT Javier Proceedings of the National Academy of Sciences 94 (13), 6670-6675, 1997 | 514 | 1997 |
Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteins BA Glaunsinger, SS Lee, M Thomas, L Banks, R Javier Oncogene 19 (46), 5270-5280, 2000 | 401 | 2000 |
Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation D Gardiol, C Kühne, B Glaunsinger, SS Lee, R Javier, L Banks Oncogene 18 (40), 5487-5496, 1999 | 398 | 1999 |
Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins SS Lee, B Glaunsinger, F Mantovani, L Banks, RT Javier Journal of virology 74 (20), 9680-9693, 2000 | 370 | 2000 |
MicroRNAs both promote and antagonize longevity in C. elegans A De Lencastre, Z Pincus, K Zhou, M Kato, SS Lee, FJ Slack Current Biology 20 (24), 2159-2168, 2010 | 346 | 2010 |
Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans AB Hwang, EA Ryu, M Artan, HW Chang, MH Kabir, HJ Nam, D Lee, ... Proceedings of the National Academy of Sciences 111 (42), E4458-E4467, 2014 | 196 | 2014 |
Two SET domain containing genes link epigenetic changes and aging in Caenorhabditis elegans Z Ni, A Ebata, E Alipanahiramandi, SS Lee Aging cell 11 (2), 315-325, 2012 | 149 | 2012 |
Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator J Li, A Ebata, Y Dong, G Rizki, T Iwata, SS Lee PLoS biology 6 (9), e233, 2008 | 147 | 2008 |
The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO G Rizki, TN Iwata, J Li, CG Riedel, CL Picard, M Jan, CT Murphy, SS Lee PLoS genetics 7 (9), e1002235, 2011 | 137 | 2011 |
Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span M Pu, Z Ni, M Wang, X Wang, JG Wood, SL Helfand, H Yu, SS Lee Genes & development 29 (7), 718-731, 2015 | 133 | 2015 |
Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein KK Frese, SS Lee, DL Thomas, IJ Latorre, RS Weiss, BA Glaunsinger, ... Oncogene 22 (5), 710-721, 2003 | 132 | 2003 |
The 14-3-3 protein FTT-2 regulates DAF-16 in Caenorhabditis elegans J Li, M Tewari, M Vidal, SS Lee Developmental biology 301 (1), 82-91, 2007 | 129 | 2007 |
Whole apple extracts increase lifespan, healthspan and resistance to stress in Caenorhabditis elegans EM Vayndorf, SS Lee, RH Liu Journal of Functional Foods 5 (3), 1235-1243, 2013 | 122 | 2013 |
The multi‐PDZ domain protein MUPP1 is a cytoplasmic ligand for the membrane‐spanning proteoglycan NG2 DS Barritt, MT Pearn, AH Zisch, SS Lee, RT Javier, EB Pasquale, ... Journal of cellular biochemistry 79 (2), 213-224, 2000 | 120 | 2000 |
Link of the unique oncogenic properties of adenovirus type 9 E4‐ORF1 to a select interaction with the candidate tumor suppressor protein ZO‐2 BA Glaunsinger, RS Weiss, SS Lee, R Javier The EMBO journal, 2001 | 116 | 2001 |
The Homeobox Protein CEH-23 Mediates Prolonged Longevity in Response to Impaired Mitochondrial Electron Transport Chain in C. elegans L Walter, A Baruah, HW Chang, HM Pace, SS Lee PLoS biology 9 (6), e1001084, 2011 | 89 | 2011 |