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Tyler Funnell
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Interfaces of malignant and immunologic clonal dynamics in ovarian cancer
AW Zhang, A McPherson, K Milne, DR Kroeger, PT Hamilton, A Miranda, ...
Cell 173 (7), 1755-1769. e22, 2018
2992018
Systematic analysis of somatic mutations impacting gene expression in 12 tumour types
J Ding, MK McConechy, HM Horlings, G Ha, F Chun Chan, T Funnell, ...
Nature communications 6 (1), 8554, 2015
1042015
Ovarian cancer mutational processes drive site-specific immune evasion
I Vázquez-García, F Uhlitz, N Ceglia, JLP Lim, M Wu, N Mohibullah, ...
Nature 612 (7941), 778-786, 2022
702022
Integrated structural variation and point mutation signatures in cancer genomes using correlated topic models
T Funnell, AW Zhang, D Grewal, S McKinney, A Bashashati, YK Wang, ...
PLoS computational biology 15 (2), e1006799, 2019
582019
CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor
T Funnell, S Tasaki, A Oloumi, S Araki, E Kong, D Yap, Y Nakayama, ...
Nature Communications 8 (1), 7, 2017
522017
Single-cell genomic variation induced by mutational processes in cancer
T Funnell, CH O’Flanagan, MJ Williams, A McPherson, S McKinney, ...
Nature 612 (7938), 106-115, 2022
472022
Cancer phylogenetic tree inference at scale from 1000s of single cell genomes
S Salehi, F Dorri, K Chern, F Kabeer, N Rusk, T Funnell, MJ Williams, ...
Peer Community Journal 3, 2023
132023
Efficient Bayesian inference of phylogenetic trees from large scale, low-depth genome-wide single-cell data
F Dorri, S Salehi, K Chern, T Funnell, M Williams, D Lai, M Andronescu, ...
bioRxiv, 2020.05. 06.058180, 2020
132020
Integrated single-nucleotide and structural variation signatures of DNA-repair deficient human cancers
T Funnell, A Zhang, YJ Shiah, D Grewal, R Lesurf, S McKinney, ...
bioRxiv, 267500, 2018
82018
Evolutionary tracking of cancer haplotypes at single-cell resolution
MJ Williams, T Funnell, CH O’Flanagan, A McPherson, S Salehi, ...
Biorxiv, 2021.06. 04.447031, 2021
72021
Immune and malignant cell phenotypes of ovarian cancer are determined by distinct mutational processes
I Vázquez-García, F Uhlitz, N Ceglia, JLP Lim, M Wu, N Mohibullah, ...
bioRxiv, 2021.08. 24.454519, 2021
62021
The impact of mutational processes on structural genomic plasticity in cancer cells
T Funnell, CH O’Flanagan, MJ Williams, A McPherson, S McKinney, ...
Biorxiv, 2021.06. 03.446999, 2021
62021
Integrated single-nucleotide and structural variation signatures of dna-repair deficient human cancers. bioRxiv
T Funnell, A Zhang, YJ Shiah, D Grewal, R Lesurf, S McKinney, ...
62018
Pilot trial of homebound hematopoietic cell transplantation
HJ Landau, E Orlando, ES Rodriguez, A Applebaum, HR Mitchell, ...
Transplantation and cellular therapy 28 (12), 832. e1-832. e7, 2022
22022
Accurate determination of CRISPR-mediated gene fitness in transplantable tumours
P Eirew, C O’Flanagan, J Ting, S Salehi, J Brimhall, B Wang, J Biele, ...
Nature Communications 13 (1), 4534, 2022
22022
The interface of malignant and immunologic clonal dynamics in high-grade serous ovarian cancer
AW Zhang, A McPherson, K Milne, DR Kroeger, PT Hamilton, A Miranda, ...
bioRxiv, 198101, 2017
22017
Scalable Log-ratio Lasso Regression Enhances Microbiome Feature Selection for Predictive Models.
T Fei, T Funnell, NR Waters, SS Raj, SM Devlin, A Dai, O Miltiadous, ...
Biorxiv: the Preprint Server for Biology, 2023
12023
A REPRODUCIBLE INFLAMMATORY BIOMARKER SIGNATURE IDENTIFIES NON-HODGKIN LYMPHOMA PATIENTS AT HIGH RISK OF CAR-T TREATMENT FAILURE ACROSS DIFFERENT COHORTS
S Raj, MA Perales, T Fei, J Fein, A Alarcon Tomas, ...
BONE MARROW TRANSPLANTATION 58 (SUPP 1), 41-42, 2023
2023
Inflammatory Biomarker Clusters Are Predictive of Response and Toxicity in Large B-Cell Lymphoma Treated with CD19 CAR-T Cell Therapy
S Raj, MA Perales, JA Fein, A Alarcon Tomas, CL Batlevi, ...
Blood 140 (Supplement 1), 648-650, 2022
2022
Characterization of genomic diversity in high grade serous ovarian and triple negative breast cancer at single cell resolution
MJ Williams, T Funnell, CH O'Flanagan, A McPherson, S Aparicio, ...
Cancer Research 82 (12_Supplement), 1597-1597, 2022
2022
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