Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100 NE Byun, M Grannan, M Bubser, RL Barry, A Thompson, J Rosanelli, ... Neuropsychopharmacology 39 (7), 1578-1593, 2014 | 122 | 2014 |
The rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants MA Mergy, R Gowrishankar, PJ Gresch, SC Gantz, J Williams, GL Davis, ... Proceedings of the National Academy of Sciences 111 (44), E4779-E4788, 2014 | 81 | 2014 |
Good riddance to dopamine: roles for the dopamine transporter in synaptic function and dopamine-associated brain disorders R Gowrishankar, MK Hahn, RD Blakely Neurochemistry international 73, 42-48, 2014 | 78 | 2014 |
A photoswitchable GPCR-based opsin for presynaptic inhibition BA Copits, R Gowrishankar, PR O’Neill, JN Li, KS Girven, JJ Yoo, ... Neuron 109 (11), 1791-1809. e11, 2021 | 66 | 2021 |
Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement R Al-Hasani, R Gowrishankar, GP Schmitz, CE Pedersen, DJ Marcus, ... Nature neuroscience 24 (10), 1414-1428, 2021 | 64 | 2021 |
Region-specific regulation of presynaptic dopamine homeostasis by D2 autoreceptors shapes the in vivo impact of the neuropsychiatric disease-associated DAT variant Val559 R Gowrishankar, PJ Gresch, GL Davis, RM Katamish, JR Riele, ... Journal of Neuroscience 38 (23), 5302-5312, 2018 | 41 | 2018 |
Genetic targeting of the amphetamine and methylphenidate-sensitive dopamine transporter: on the path to an animal model of attention-deficit hyperactivity disorder MA Mergy, R Gowrishankar, GL Davis, TN Jessen, J Wright, ... Neurochemistry international 73, 56-70, 2014 | 37 | 2014 |
Functional coding variation in the presynaptic dopamine transporter associated with neuropsychiatric disorders drives enhanced motivation and context-dependent impulsivity in mice GL Davis, A Stewart, GD Stanwood, R Gowrishankar, MK Hahn, ... Behavioural brain research 337, 61-69, 2018 | 34 | 2018 |
Serotonin transporter inhibition and 5-HT2C receptor activation drive loss of cocaine-induced locomotor activation in DAT Val559 mice A Stewart, GL Davis, PJ Gresch, RM Katamish, R Peart, MJ Rabil, ... Neuropsychopharmacology 44 (5), 994-1006, 2019 | 20 | 2019 |
Phylogenetic comparison of exonic US4, US7 and UL44 regions of clinical herpes simplex virus type 1 isolates showed lack of association between their anatomic sites of … A Harishankar, M Jambulingam, R Gowrishankar, A Venkatachalam, ... Virology journal 9, 1-8, 2012 | 8 | 2012 |
Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters A Stewart, FP Mayer, R Gowrishankar, GL Davis, LB Areal, PJ Gresch, ... Molecular Psychiatry 27 (12), 4869-4880, 2022 | 7 | 2022 |
An open-source platform for head-fixed operant and consummatory behavior A Gordon-Fennell, JM Barbakh, MKT Utley, S Singh, P Bazzino, ... Elife 12, e86183, 2023 | 6 | 2023 |
Sex and Circuit Specific Dopamine Transporter Regulation Underlies Unique Behavioral Trajectories of Functional SLC6A3 Coding Variation A Stewart, FP Mayer, R Gowrishankar, GL Davis, LB Areal, PJ Gresch, ... bioRxiv, 2021.11. 02.466932, 2021 | 5 | 2021 |
Medial accumbens shell spiny projection neurons encode relative reward preference CE Pedersen, R Gowrishankar, SC Piantadosi, DC Castro, MM Gray, ... bioRxiv, 2022.09. 18.508426, 2022 | 4 | 2022 |
Kappa opioid receptor antagonism rescues genetic perturbation of dopamine homeostasis: Molecular, physiological and behavioral consequences FP Mayer, A Stewart, DR Varman, AE Moritz, JD Foster, AW Owens, ... bioRxiv, 2023 | 3 | 2023 |
Unlocking opioid neuropeptide dynamics with genetically-encoded biosensors L Tian, C Dong, R Gowrishankar, Y Jin, X He, A Gupta, H Wang, N Atasoy, ... | 2 | 2023 |
A photoswitchable GPCR-based opsin for presynaptic silencing BA Copits, PR O’Neill, R Gowrishankar, JJ Yoo, X Meshik, KE Parker, ... bioRxiv, 2021.02. 19.432008, 2021 | 2 | 2021 |
Defining circuit-specific roles for G protein-coupled receptors in aversive learning R Gowrishankar, MR Bruchas Current opinion in behavioral sciences 26, 146-156, 2019 | 2 | 2019 |
Kappa-opioid receptor activation reinstates nicotine self-administration in mice R Gowrishankar, A Gomez, M Waliki, MR Bruchas Addiction neuroscience 2, 100017, 2022 | 1 | 2022 |
Ventral tegmental area GABAergic inhibition of ventral accumbens shell cholinergic interneurons promotes reward reinforcement R Al-Hasani, R Gowrishankar, GP Schmitz, CE Pedersen, DJ Marcus, ... Nature neuroscience 24 (10), 1414, 2021 | 1 | 2021 |