| Asymmetrical roles of zinc fingers in dynamic DNA-scanning process by the inducible transcription factor Egr-1 L Zandarashvili, D Vuzman, A Esadze, Y Takayama, D Sahu, Y Levy, ... Proceedings of the National Academy of Sciences 109 (26), E1724-E1732, 2012 | 114 | 2012 |
| Balancing between affinity and speed in target DNA search by zinc-finger proteins via modulation of dynamic conformational ensemble L Zandarashvili, A Esadze, D Vuzman, CA Kemme, Y Levy, J Iwahara Proceedings of the National Academy of Sciences 112 (37), E5142-E5149, 2015 | 102 | 2015 |
| Dynamics of Lysine Side-Chain Amino Groups in a Protein Studied by Heteronuclear 1H−15N NMR Spectroscopy A Esadze, DW Li, T Wang, R Brüschweiler, J Iwahara Journal of the American Chemical Society 133 (4), 909-919, 2011 | 92 | 2011 |
| Positive and negative impacts of nonspecific sites during target location by a sequence-specific DNA-binding protein: origin of the optimal search at physiological ionic strength A Esadze, CA Kemme, AB Kolomeisky, J Iwahara Nucleic acids research 42 (11), 7039-7046, 2014 | 76 | 2014 |
| Direct observation of the ion-pair dynamics at a protein–DNA interface by NMR spectroscopy KM Anderson, A Esadze, M Manoharan, R Brüschweiler, DG Gorenstein, ... Journal of the American Chemical Society 135 (9), 3613-3619, 2013 | 65 | 2013 |
| Facilitated diffusion mechanisms in DNA base excision repair and transcriptional activation A Esadze, JT Stivers Chemical reviews 118 (23), 11298-11323, 2018 | 61 | 2018 |
| Changes in conformational dynamics of basic side chains upon protein–DNA association A Esadze, C Chen, L Zandarashvili, S Roy, BM Pettitt, J Iwahara Nucleic acids research 44 (14), 6961-6970, 2016 | 58 | 2016 |
| Stopped-flow fluorescence kinetic study of protein sliding and intersegment transfer in the target DNA search process A Esadze, J Iwahara Journal of molecular biology 426 (1), 230-244, 2014 | 57 | 2014 |
| Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1 L Zandarashvili, MA White, A Esadze, J Iwahara FEBS letters 589 (15), 1748-1753, 2015 | 45 | 2015 |
| Dynamic equilibria of short-range electrostatic interactions at molecular interfaces of protein–DNA complexes C Chen, A Esadze, L Zandarashvili, D Nguyen, BM Pettitt, J Iwahara The journal of physical chemistry letters 6 (14), 2733-2737, 2015 | 40 | 2015 |
| Physicochemical properties of ion pairs of biological macromolecules J Iwahara, A Esadze, L Zandarashvili Biomolecules 5 (4), 2435-2463, 2015 | 38 | 2015 |
| AP-endonuclease 1 accelerates turnover of human 8-oxoguanine DNA glycosylase by preventing retrograde binding to the abasic-site product A Esadze, G Rodriguez, SL Cravens, JT Stivers Biochemistry 56 (14), 1974-1986, 2017 | 35 | 2017 |
| NMR studies on the dynamics of hydrogen bonds and ion pairs involving lysine side chains of proteins L Zandarashvili, A Esadze, J Iwahara Advances in Protein Chemistry and Structural Biology 93, 37-80, 2013 | 34 | 2013 |
| Influence of quasi-specific sites on kinetics of target DNA search by a sequence-specific DNA-binding protein CA Kemme, A Esadze, J Iwahara Biochemistry 54 (44), 6684-6691, 2015 | 24 | 2015 |
| Disordered N-terminal domain of human uracil DNA glycosylase (hUNG2) enhances DNA translocation G Rodriguez, A Esadze, BP Weiser, JD Schonhoft, PA Cole, JT Stivers ACS chemical biology 12 (9), 2260-2263, 2017 | 23 | 2017 |
| Measurement of nanoscale DNA translocation by uracil DNA glycosylase in human cells A Esadze, G Rodriguez, BP Weiser, PA Cole, JT Stivers Nucleic acids research 45 (21), 12413-12424, 2017 | 22 | 2017 |
| Effective strategy to assign 1H-15N heteronuclear correlation NMR signals from lysine side-chain NH3 + groups of proteins at low temperature A Esadze, L Zandarashvili, J Iwahara Journal of biomolecular NMR 60, 23-27, 2014 | 20 | 2014 |
| Residence times of molecular complexes in solution from NMR data of intermolecular hydrogen-bond scalar coupling L Zandarashvili, A Esadze, CA Kemme, A Chattopadhyay, D Nguyen, ... The journal of physical chemistry letters 7 (5), 820-824, 2016 | 16 | 2016 |
| A chemical approach for site-specific identification of NMR signals from protein side-chain NH3 + groups forming intermolecular ion pairs in protein … KM Anderson, D Nguyen, A Esadze, L Zandrashvili, DG Gorenstein, ... Journal of biomolecular NMR 62, 1-5, 2015 | 14 | 2015 |
| NMR-based investigations into target DNA search processes of proteins J Iwahara, L Zandarashvili, CA Kemme, A Esadze Methods 148, 57-66, 2018 | 13 | 2018 |
Junji IwaharaProfessor, University of Texas Medical BranchVerified email at utmb.edu
