| Human PAD4 regulates histone arginine methylation levels via demethylimination Y Wang, J Wysocka, J Sayegh, YH Lee, JR Perlin, L Leonelli, ... Science 306 (5694), 279-283, 2004 | 1213 | 2004 |
| Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy D Peng, I Kryczek, N Nagarsheth, L Zhao, S Wei, W Wang, Y Sun, E Zhao, ... Nature 527 (7577), 249-253, 2015 | 1067 | 2015 |
| WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development J Wysocka, T Swigut, TA Milne, Y Dou, X Zhang, AL Burlingame, ... Cell 121 (6), 859-872, 2005 | 961 | 2005 |
| Regulation of MLL1 H3K4 methyltransferase activity by its core components Y Dou, TA Milne, AJ Ruthenburg, S Lee, JW Lee, GL Verdine, CD Allis, ... Nature structural & molecular biology 13 (8), 713-719, 2006 | 866 | 2006 |
| Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF Y Dou, TA Milne, AJ Tackett, ER Smith, A Fukuda, J Wysocka, CD Allis, ... Cell 121 (6), 873-885, 2005 | 790 | 2005 |
| Hijacked in cancer: the KMT2 (MLL) family of methyltransferases RC Rao, Y Dou Nature Reviews Cancer 15 (6), 334-346, 2015 | 602 | 2015 |
| Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors TA Milne, CM Hughes, R Lloyd, Z Yang, O Rozenblatt-Rosen, Y Dou, ... Proceedings of the National Academy of Sciences 102 (3), 749-754, 2005 | 534 | 2005 |
| Epigenetic regulation of the alternatively activated macrophage phenotype M Ishii, H Wen, CAS Corsa, T Liu, AL Coelho, RM Allen, WF Carson IV, ... Blood, The Journal of the American Society of Hematology 114 (15), 3244-3254, 2009 | 510 | 2009 |
| Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions AJ Ruthenburg, H Li, TA Milne, S Dewell, RK McGinty, M Yuen, ... Cell 145 (5), 692-706, 2011 | 393 | 2011 |
| IL-22+ CD4+ T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L I Kryczek, Y Lin, N Nagarsheth, D Peng, L Zhao, E Zhao, L Vatan, ... Immunity 40 (5), 772-784, 2014 | 389 | 2014 |
| Effector T cells abrogate stroma-mediated chemoresistance in ovarian cancer W Wang, I Kryczek, L Dostál, H Lin, L Tan, L Zhao, F Lu, S Wei, T Maj, ... Cell 165 (5), 1092-1105, 2016 | 388 | 2016 |
| PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation D Hyllus, C Stein, K Schnabel, E Schiltz, A Imhof, Y Dou, J Hsieh, ... Genes & development 21 (24), 3369-3380, 2007 | 343 | 2007 |
| Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia F Cao, EC Townsend, H Karatas, J Xu, L Li, S Lee, L Liu, Y Chen, ... Molecular cell 53 (2), 247-261, 2014 | 319 | 2014 |
| MLL associates specifically with a subset of transcriptionally active target genes TA Milne, Y Dou, ME Martin, HW Brock, RG Roeder, JL Hess Proceedings of the National Academy of Sciences 102 (41), 14765-14770, 2005 | 277 | 2005 |
| PRC2 epigenetically silences Th1-type chemokines to suppress effector T-cell trafficking in colon cancer N Nagarsheth, D Peng, I Kryczek, K Wu, W Li, E Zhao, L Zhao, S Wei, ... Cancer research 76 (2), 275-282, 2016 | 250 | 2016 |
| Epigenetic regulation of immune cell functions during post-septic immunosuppression WF Carson, KA Cavassani, Y Dou, SL Kunkel Epigenetics 6 (3), 273-283, 2011 | 246 | 2011 |
| MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1 X Li, CAS Corsa, PW Pan, L Wu, D Ferguson, X Yu, J Min, Y Dou Molecular and cellular biology 30 (22), 5335-5347, 2010 | 233 | 2010 |
| The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network X Li, L Li, R Pandey, JS Byun, K Gardner, Z Qin, Y Dou Cell stem cell 11 (2), 163-178, 2012 | 231 | 2012 |
| Structural basis for activity regulation of MLL family methyltransferases Y Li, J Han, Y Zhang, F Cao, Z Liu, S Li, J Wu, C Hu, Y Wang, J Shuai, ... Nature 530 (7591), 447-452, 2016 | 229 | 2016 |
| NSUN2‐mediated m5C methylation and METTL3/METTL14‐mediated m6A methylation cooperatively enhance p21 translation Q Li, X Li, H Tang, B Jiang, Y Dou, M Gorospe, W Wang Journal of cellular biochemistry 118 (9), 2587-2598, 2017 | 199 | 2017 |
Robert RoederProfessor of Biochemistry and Molecular Biology, The Rockefeller UniversityVerified email at rockefeller.edu
