Nkx2. 2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming JB Papizan, RA Singer, SI Tschen, S Dhawan, JM Friel, SB Hipkens, ... Genes & development 25 (21), 2291-2305, 2011 | 224 | 2011 |
The long noncoding RNA paupar modulates PAX6 regulatory activities to promote alpha cell development and function RA Singer, L Arnes, Y Cui, J Wang, Y Gao, MA Guney, ... Cell metabolism 30 (6), 1091-1106. e8, 2019 | 53 | 2019 |
Genetic evidence that Nkx2. 2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development AJ Churchill, GD Gutierrez, RA Singer, DS Lorberbaum, KA Fischer, ... Elife 6, e20010, 2017 | 50 | 2017 |
Highly-multiplexed volumetric mapping with Raman dye imaging and tissue clearing L Shi, M Wei, Y Miao, N Qian, L Shi, RA Singer, RKP Benninger, W Min Nature biotechnology 40 (3), 364-373, 2022 | 48 | 2022 |
Murine perinatal β-cell proliferation and the differentiation of human stem cell–derived insulin-expressing cells require NEUROD1 AI Romer, RA Singer, L Sui, D Egli, L Sussel Diabetes 68 (12), 2259-2271, 2019 | 46 | 2019 |
The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration KR Anderson, RA Singer, DA Balderes, L Hernandez-Lagunas, ... Development 138 (15), 3213-3224, 2011 | 41 | 2011 |
Islet long noncoding RNAs: a playbook for discovery and characterization RA Singer, L Sussel Diabetes 67 (8), 1461-1470, 2018 | 32 | 2018 |
Noncoding RNAs in β cell biology RA Singer, L Arnes, L Sussel Current Opinion in Endocrinology, Diabetes and Obesity 22 (2), 77-85, 2015 | 22 | 2015 |
A retrotransposon insertion in the 5′ regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse F Lugani, R Arora, N Papeta, A Patel, Z Zheng, R Sterken, RA Singer, ... PLoS genetics 9 (2), e1003206, 2013 | 20 | 2013 |
Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing mouse pancreas A Theis, RA Singer, D Garofalo, A Paul, A Narayana, L Sussel Development 148 (6), dev192401, 2021 | 7 | 2021 |
Long noncoding RNAs are critical regulators of pancreatic islet development and function RA Singer Columbia University, 2019 | | 2019 |