Conformational biosensors reveal GPCR signalling from endosomes R Irannejad, JC Tomshine, JR Tomshine, M Chevalier, JP Mahoney, ... Nature 495 (7442), 534-538, 2013 | 823 | 2013 |
GPCR signaling along the endocytic pathway R Irannejad, M Von Zastrow Current opinion in cell biology 27, 109-116, 2014 | 233 | 2014 |
Functional selectivity of GPCR-directed drug action through location bias R Irannejad, V Pessino, D Mika, B Huang, PB Wedegaertner, M Conti, ... Nature chemical biology 13 (7), 799-806, 2017 | 207 | 2017 |
Assembly and trafficking of heterotrimeric G proteins Y Marrari, M Crouthamel, R Irannejad, PB Wedegaertner Biochemistry 46 (26), 7665-7677, 2007 | 202 | 2007 |
G protein-coupled receptor (GPCR) signaling via heterotrimeric G proteins from endosomes NG Tsvetanova, R Irannejad, M von Zastrow Journal of Biological Chemistry 290 (11), 6689-6696, 2015 | 171 | 2015 |
Effects of endocytosis on receptor-mediated signaling R Irannejad, NG Tsvetanova, BT Lobingier, M Von Zastrow Current opinion in cell biology 35, 137-143, 2015 | 159 | 2015 |
Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy CA Nash, W Wei, R Irannejad, AV Smrcka Elife 8, e48167, 2019 | 100 | 2019 |
Regulation of constitutive cargo transport from the trans-Golgi network to plasma membrane by Golgi-localized G protein βγ subunits R Irannejad, PB Wedegaertner Journal of biological chemistry 285 (42), 32393-32404, 2010 | 75 | 2010 |
The α-arrestin ARRDC3 regulates the endosomal residence time and intracellular signaling of the β2-adrenergic receptor X Tian, R Irannejad, SL Bowman, Y Du, MA Puthenveedu, M von Zastrow, ... Journal of Biological Chemistry 291 (28), 14510-14525, 2016 | 67 | 2016 |
Retromer endosome exit domains serve multiple trafficking destinations and regulate local G protein activation by GPCRs KC Varandas, R Irannejad, M von Zastrow Current Biology 26 (23), 3129-3142, 2016 | 54 | 2016 |
G protein βγ subunits regulate cardiomyocyte hypertrophy through a perinuclear Golgi phosphatidylinositol 4-phosphate hydrolysis pathway S Malik, RG Derubio, M Trembley, R Irannejad, PB Wedegaertner, ... Molecular biology of the cell 26 (6), 1188-1198, 2015 | 48 | 2015 |
G protein-regulated endocytic trafficking of adenylyl cyclase type 9 AM Lazar, R Irannejad, TA Baldwin, AB Sundaram, JS Gutkind, A Inoue, ... Elife 9, e58039, 2020 | 46 | 2020 |
Emerging role of compartmentalized G protein-coupled receptor signaling in the cardiovascular field B Plouffe, ARB Thomsen, R Irannejad ACS pharmacology & translational science 3 (2), 221-236, 2020 | 40 | 2020 |
Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies SW Yee, A Stecula, HC Chien, L Zou, EV Feofanova, M van Borselen, ... PLoS genetics 15 (9), e1008208, 2019 | 24 | 2019 |
The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus NM Puri, GR Romano, TY Lin, QN Mai, R Irannejad Elife 11, e75468, 2022 | 23 | 2022 |
Genetically encoding quinoline reverses chromophore charge and enables fluorescent protein brightening in acidic vesicles C Fu, T Kobayashi, N Wang, C Hoppmann, B Yang, R Irannejad, L Wang Journal of the American Chemical Society 140 (35), 11058-11066, 2018 | 18 | 2018 |
Investigating signaling consequences of GPCR trafficking in the endocytic pathway R Irannejad, SJ Kotowski, M von Zastrow Methods in enzymology 535, 403-418, 2014 | 10 | 2014 |
Cardiac contraction and relaxation are regulated by distinct subcellular cAMP pools TY Lin, QN Mai, H Zhang, E Wilson, HC Chien, SW Yee, KM Giacomini, ... Nature Chemical Biology 20 (1), 62-73, 2024 | 7 | 2024 |
Inhibition of muscarinic receptor signaling protects human enteric inhibitory neurons against platin chemotherapy toxicity MN Richter, S Farahvashi, RM Samuel, H Majd, AK Chemel, JT Ramirez, ... bioRxiv, 2023.03. 08.531806, 2023 | 3 | 2023 |
The OCT2 Transporter Regulates Dopamine D1 Receptor Signaling at the Golgi Apparatus NM Puri, GR Romano, TY Lin, QN Mai, R Irannejad bioRxiv, 2020.11. 23.394445, 2020 | 2* | 2020 |