Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia BT Messmer, E Albesiano, DG Efremov, F Ghiotto, SL Allen, J Kolitz, ... The Journal of experimental medicine 200 (4), 519-525, 2004 | 537 | 2004 |
The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells PG Longo, L Laurenti, S Gobessi, S Sica, G Leone, DG Efremov Blood, The Journal of the American Society of Hematology 111 (2), 846-855, 2008 | 377 | 2008 |
Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells A Petlickovski, L Laurenti, X Li, S Marietti, P Chiusolo, S Sica, G Leone, ... Blood 105 (12), 4820-4827, 2005 | 331 | 2005 |
Somatic Hypermutation, Clonal Diversity, and Preferential Expression of the VH 51p1/VL kv325 Immunoglobulin Gene Combination in Hepatitis C Virus … M Ivanovski, F Silvestri, G Pozzato, S Anand, C Mazzaro, OR Burrone, ... Blood, The Journal of the American Society of Hematology 91 (7), 2433-2442, 1998 | 297 | 1998 |
Bruton’s tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL) JA Woyach, E Bojnik, AS Ruppert, MR Stefanovski, VM Goettl, ... Blood, The Journal of the American Society of Hematology 123 (8), 1207-1213, 2014 | 259 | 2014 |
Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells S Gobessi, L Laurenti, PG Longo, L Carsetti, V Berno, S Sica, G Leone, ... Leukemia 23 (4), 686-697, 2009 | 249 | 2009 |
CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential S Deaglio, T Vaisitti, S Aydin, L Bergui, G D'Arena, L Bonello, P Omedé, ... Blood, The Journal of the American Society of Hematology 110 (12), 4012-4021, 2007 | 241 | 2007 |
ZAP-70 enhances B-cell–receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells S Gobessi, L Laurenti, PG Longo, S Sica, G Leone, DG Efremov Blood 109 (5), 2032-2039, 2007 | 230 | 2007 |
Regression of monoclonal B‐cell expansion in patients affected by mixed cryoglobulinemia responsive to α‐interferon therapy C Mazzaro, F Franzin, P Tulissi, E Pussini, M Crovatto, GS Carniello, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 1996 | 229 | 1996 |
B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia X Yan, E Albesiano, N Zanesi, S Yancopoulos, A Sawyer, E Romano, ... Proceedings of the National Academy of Sciences 103 (31), 11713-11718, 2006 | 197 | 2006 |
The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease PG Longo, L Laurenti, S Gobessi, A Petlickovski, M Pelosi, P Chiusolo, ... Leukemia 21 (1), 110-120, 2007 | 190 | 2007 |
Clonal B‐cell expansions in peripheral blood of HCV‐infected patients F Franzin, DG Efremov, G Pozzato, P Tulissi, F Batista, OR Burrone British journal of haematology 90 (3), 548-552, 1995 | 181 | 1995 |
The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Eμ-TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling M Suljagic, PG Longo, S Bennardo, E Perlas, G Leone, L Laurenti, ... Blood, The Journal of the American Society of Hematology 116 (23), 4894-4905, 2010 | 179 | 2010 |
Association between molecular lesions and specific B-cell receptor subsets in chronic lymphocytic leukemia D Rossi, V Spina, R Bomben, S Rasi, M Dal-Bo, A Bruscaggin, FM Rossi, ... Blood, The Journal of the American Society of Hematology 121 (24), 4902-4905, 2013 | 164 | 2013 |
Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study R Bomben, M Dal Bo, D Capello, F Forconi, R Maffei, L Laurenti, D Rossi, ... British journal of haematology 144 (4), 492-506, 2009 | 152 | 2009 |
BCR signaling inhibitors differ in their ability to overcome Mcl-1–mediated resistance of CLL B cells to ABT-199 K Bojarczuk, BK Sasi, S Gobessi, I Innocenti, G Pozzato, L Laurenti, ... Blood, The Journal of the American Society of Hematology 127 (25), 3192-3201, 2016 | 130 | 2016 |
Mild and severe beta-thalassemia among homozygotes from Turkey: identification of the types by hybridization of amplified DNA with synthetic probes JC Diaz-Chico, KG Yang, TA Stoming, DG Efremov, A Kutlar, F Kutlar, ... | 110 | 1988 |
Signaling pathways activated by antigen-receptor engagement in chronic lymphocytic leukemia B-cells DG Efremov, S Gobessi, PG Longo Autoimmunity reviews 7 (2), 102-108, 2007 | 108 | 2007 |
The miR-17∼ 92 family regulates the response to Toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes R Bomben, S Gobessi, M Dal Bo, S Volinia, D Marconi, E Tissino, ... Leukemia 26 (7), 1584-1593, 2012 | 103 | 2012 |
Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT R Negro, S Gobessi, PG Longo, Y He, ZY Zhang, L Laurenti, DG Efremov Blood, The Journal of the American Society of Hematology 119 (26), 6278-6287, 2012 | 95 | 2012 |