| Top down characterization of larger proteins (45 kDa) by electron capture dissociation mass spectrometry Y Ge, BG Lawhorn, M ElNaggar, E Strauss, JH Park, TP Begley, ... Journal of the American Chemical Society 124 (4), 672-678, 2002 | 472 | 2002 |
| The biosynthesis of coenzyme A in bacteria TP Begley, C Kinsland, E Strauss Vitamins & Hormones 61, 157-171, 2001 | 255 | 2001 |
| The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme A, a coenzyme A antimetabolite E Strauss, TP Begley Journal of Biological Chemistry 277 (50), 48205-48209, 2002 | 156 | 2002 |
| Phosphopantothenoylcysteine synthetase from Escherichia coli Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria E Strauss, C Kinsland, Y Ge, FW McLafferty, TP Begley Journal of Biological Chemistry 276 (17), 13513-13516, 2001 | 131 | 2001 |
| Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated C Spry, C Macuamule, Z Lin, KG Virga, RE Lee, E Strauss, KJ Saliba PloS one 8 (2), e54974, 2013 | 111 | 2013 |
| Characterization of a new pantothenate kinase isoform from Helicobacter pylori LA Brand, E Strauss Journal of Biological Chemistry 280 (21), 20185-20188, 2005 | 95 | 2005 |
| Functional copper at the acetyl-CoA synthase active site J Seravalli, W Gu, A Tam, E Strauss, TP Begley, SP Cramer, ... Proceedings of the National Academy of Sciences 100 (7), 3689-3694, 2003 | 90 | 2003 |
| Crystal structure of a type III pantothenate kinase: insight into the mechanism of an essential coenzyme A biosynthetic enzyme universally distributed in bacteria K Yang, Y Eyobo, LA Brand, D Martynowski, D Tomchick, E Strauss, ... Journal of bacteriology 188 (15), 5532-5540, 2006 | 79 | 2006 |
| Coenzyme A biosynthesis and enzymology E Strauss Comprehensive Natural Products II Chemistry and Biology, L. Mander and H.-W …, 2010 | 74 | 2010 |
| Recent advances in targeting coenzyme A biosynthesis and utilization for antimicrobial drug development. WJ Moolman, M de Villiers, E Strauss Biochemical Society transactions 42 (4), 1080-1086, 2014 | 71 | 2014 |
| Structural Modification of Pantothenamides Counteracts Degradation by Pantetheinase and Improves Antiplasmodial Activity M de Villiers, C Macuamule, C Spry, YM Hyun, E Strauss, KJ Saliba ACS Medicinal Chemistry Letters 4 (8), 784-789, 2013 | 70 | 2013 |
| Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis A Ruiz, A González, I Muñoz, R Serrano, JA Abrie, E Strauss, J Ariño Nature chemical biology 5 (12), 920-928, 2009 | 62 | 2009 |
| Coenzyme A: to make it or uptake it? OCM Sibon, E Strauss Nature Reviews Molecular Cell Biology 17 (10), 605-606, 2016 | 59 | 2016 |
| A Pantetheinase-Resistant Pantothenamide with Potent, On-Target, and Selective Antiplasmodial Activity CJ Macuamule, ET Tjhin, CE Jana, L Barnard, L Koekemoer, M de Villiers, ... Antimicrobial agents and chemotherapy 59 (6), 3666-3668, 2015 | 50 | 2015 |
| The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis R van der Westhuyzen, JC Hammons, JL Meier, S Dahesh, ... Chemistry & biology 19 (5), 559-571, 2012 | 50 | 2012 |
| Michael acceptor-containing coenzyme A analogues as inhibitors of the atypical coenzyme A disulfide reductase from Staphylococcus aureus R van der Westhuyzen, E Strauss Journal of the American Chemical Society 132 (37), 12853-12855, 2010 | 47 | 2010 |
| Pantothenate utilization by Plasmodium as a target for antimalarial chemotherapy C Spry, DA Van Schalkwyk, E Strauss, KJ Saliba Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2010 | 46 | 2010 |
| Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis M Villiers, L Barnard, L Koekemoer, JL Snoep, E Strauss FEBS Journal 281 (20), 4731-4753, 2014 | 45 | 2014 |
| Mechanistic studies on phosphopantothenoylcysteine decarboxylase E Strauss, TP Begley Journal of the American Chemical Society 123 (26), 6449-6450, 2001 | 45 | 2001 |
| Mechanistic studies on phosphopantothenoylcysteine decarboxylase: trapping of an enethiolate intermediate with a mechanism-based inactivating agent E Strauss, H Zhai, LA Brand, FW McLafferty, TP Begley Biochemistry 43 (49), 15520-15533, 2004 | 43 | 2004 |
Kevin J SalibaProfessor, Research School of Biology, Australian National UniversityVerified email at anu.edu.au
