| Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury H Yan, X Duan, H Pan, N Holguin, MF Rai, A Akk, LE Springer, ... Proceedings of the National Academy of Sciences 113 (41), E6199-E6208, 2016 | 143 | 2016 |
| Adipose tissue is a critical regulator of osteoarthritis KH Collins, KL Lenz, EN Pollitt, D Ferguson, I Hutson, LE Springer, ... Proceedings of the National Academy of Sciences 118 (1), e2021096118, 2021 | 107 | 2021 |
| Neutrophil proteases promote experimental abdominal aortic aneurysm via extracellular trap release and plasmacytoid dendritic cell activation H Yan, HF Zhou, A Akk, Y Hu, LE Springer, TL Ennis, CTN Pham Arteriosclerosis, thrombosis, and vascular biology 36 (8), 1660-1669, 2016 | 104 | 2016 |
| Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis H Zhou, H Yan, H Pan, KK Hou, A Akk, LE Springer, Y Hu, JS Allen, ... The Journal of clinical investigation 124 (10), 4363-4374, 2014 | 100 | 2014 |
| Fumagillin Prodrug Nanotherapy Suppresses Macrophage Inflammatory Response via Endothelial Nitric Oxide H Zhou, H Yan, Y Hu, LE Springer, X Yang, SA Wickline, D Pan, ... ACS nano 8 (7), 7305-7317, 2014 | 88 | 2014 |
| CD43-mediated IFN-γ production by CD8+ T cells promotes abdominal aortic aneurysm in mice H Zhou, H Yan, JL Cannon, LE Springer, JM Green, CTN Pham The Journal of Immunology 190 (10), 5078-5085, 2013 | 62 | 2013 |
| Fibrinogen-specific antibody induces abdominal aortic aneurysm in mice through complement lectin pathway activation H Zhou, H Yan, P Bertram, Y Hu, LE Springer, RW Thompson, JA Curci, ... Proceedings of the National Academy of Sciences 110 (46), E4335-E4344, 2013 | 54 | 2013 |
| Neutrophil extracellular traps enhance early inflammatory response in sendai virus-induced asthma phenotype A Akk, LE Springer, CTN Pham Frontiers in immunology 7, 206432, 2016 | 32 | 2016 |
| A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery YR Choi, KH Collins, LE Springer, L Pferdehirt, AK Ross, CL Wu, ... Science Advances 7 (36), eabj1414, 2021 | 29 | 2021 |
| Complement activation on neutrophils initiates endothelial adhesion and extravasation A Akk, LE Springer, L Yang, S Hamilton-Burdess, JD Lambris, H Yan, ... Molecular immunology 114, 629-642, 2019 | 21 | 2019 |
| Anti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice H Pan, RU Palekar, KK Hou, J Bacon, H Yan, LE Springer, A Akk, L Yang, ... International Journal of Nanomedicine, 5187-5205, 2018 | 21 | 2018 |
| Clinicomolecular identification of conserved and individualized features of granulomatous uveitis LM Hassman, MA Paley, E Esaulova, GL Paley, PA Ruzycki, N Linskey, ... Ophthalmology science 1 (1), 100010, 2021 | 9 | 2021 |
| Safety profile of rapamycin perfluorocarbon nanoparticles for preventing cisplatin-induced kidney injury Q Zhou, J Doherty, A Akk, LE Springer, P Fan, I Spasojevic, GV Halade, ... Nanomaterials 12 (3), 336, 2022 | 8 | 2022 |
| Nanotherapy targeting NF-κB attenuates acute pain after joint injury H Yan, X Duan, KH Collins, LE Springer, F Guilak, SA Wickline, MF Rai, ... Precision nanomedicine 2 (1), 245, 2019 | 6 | 2019 |
| Hydrogel encapsulation of genome-engineered stem cells for long-term self-regulating anti-cytokine therapy KH Collins, L Pferdehirt, LS Saleh, A Savadipour, LE Springer, KL Lenz, ... Gels 9 (2), 169, 2023 | 5 | 2023 |
| Non-invasive monitoring of arthritis treatment response via targeting of tyrosine-phosphorylated annexin A2 in chondrocytes SWD Tsen, LE Springer, K Sharmah Gautam, R Tang, K Liang, G Sudlow, ... Arthritis Research & Therapy 23, 1-13, 2021 | 3 | 2021 |
| Fat implantation in lipodystrophic mice restores susceptibility to joint injury and osteoarthritis independent of body weight KH Collins, KL Lenz, EN Pollitt, D Ferguson, I Hutson, LE Springer, ... Osteoarthritis and Cartilage 29, S14-S15, 2021 | 2 | 2021 |
| Highly expanded clones representing different lymphocyte lineages are present in individual patients with granulomatous uveitis M Paley, LM Hassman, E Esaulova, GL Paley, J Laurent, L Springer, ... Investigative Ophthalmology & Visual Science 61 (7), 3661-3661, 2020 | 2 | 2020 |
| Side-chain modification of collagen-targeting peptide prevents dye aggregation for improved molecular imaging of arthritic joints MS Michie, B Xu, G Sudlow, LE Springer, CTN Pham, S Achilefu Journal of Photochemistry and Photobiology A: Chemistry 424, 113624, 2022 | 1 | 2022 |
| Efficacy of Targeted Janus Kinase (JAK) Inhibition by Tofacitinib in Birdshot Chorioretinitis LM Hassman, M Paley, E Esaulova, J Laurent, L Springer, M Artyomov, ... Investigative Ophthalmology & Visual Science 61 (7), 5350-5350, 2020 | 1 | 2020 |
