| The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer RJA Bell, HT Rube, A Kreig, A Mancini, SD Fouse, RP Nagarajan, S Choi, ... Science 348 (6238), 1036-1039, 2015 | 572 | 2015 |
| Understanding TERT promoter mutations: a common path to immortality RJA Bell, HT Rube, A Xavier-Magalhaes, BM Costa, A Mancini, JS Song, ... Molecular Cancer Research 14 (4), 315-323, 2016 | 288 | 2016 |
| General inflaton potentials in supergravity R Kallosh, A Linde, T Rube Physical Review D—Particles, Fields, Gravitation, and Cosmology 83 (4), 043507, 2011 | 271 | 2011 |
| Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape JG Camp, CL Frank, CR Lickwar, H Guturu, T Rube, AM Wenger, J Chen, ... Genome research 24 (9), 1504-1516, 2014 | 133 | 2014 |
| Chaotic inflation and supersymmetry breaking R Kallosh, A Linde, KA Olive, T Rube Physical Review D—Particles, Fields, Gravitation, and Cosmology 84 (8), 083519, 2011 | 133 | 2011 |
| Measuring DNA mechanics on the genome scale A Basu, DG Bobrovnikov, Z Qureshi, T Kayikcioglu, TTM Ngo, A Ranjan, ... Nature 589 (7842), 462-467, 2021 | 103 | 2021 |
| Accurate and sensitive quantification of protein-DNA binding affinity C Rastogi, HT Rube, JF Kribelbauer, J Crocker, RE Loker, GD Martini, ... Proceedings of the National Academy of Sciences 115 (16), E3692-E3701, 2018 | 99 | 2018 |
| AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines L Zhang, JA Zuris, R Viswanathan, JN Edelstein, R Turk, B Thommandru, ... Nature communications 12 (1), 3908, 2021 | 91 | 2021 |
| Prediction of protein–ligand binding affinity from sequencing data with interpretable machine learning HT Rube, C Rastogi, S Feng, JF Kribelbauer, A Li, B Becerra, LAN Melo, ... Nature biotechnology 40 (10), 1520-1527, 2022 | 65 | 2022 |
| Sequence features accurately predict genome-wide MeCP2 binding in vivo HT Rube, W Lee, M Hejna, H Chen, DH Yasui, JF Hess, JM LaSalle, ... Nature communications 7 (1), 11025, 2016 | 50 | 2016 |
| A unified approach for quantifying and interpreting DNA shape readout by transcription factors HT Rube, C Rastogi, JF Kribelbauer, HJ Bussemaker Molecular systems biology 14 (2), e7902, 2018 | 42 | 2018 |
| Nearly supersymmetric dark atoms SR Behbahani, M Jankowiak, T Rube, JG Wacker Advances in High Energy Physics 2011 (1), 709492, 2011 | 38 | 2011 |
| SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site L Zhang, GD Martini, HT Rube, JF Kribelbauer, C Rastogi, VD FitzPatrick, ... Genome research 28 (1), 111-121, 2018 | 37 | 2018 |
| Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes L Zhang, HT Rube, CA Vakulskas, MA Behlke, HJ Bussemaker, MA Pufall Nucleic acids research 48 (9), 5037-5053, 2020 | 34 | 2020 |
| Context-dependent gene regulation by homeodomain transcription factor complexes revealed by shape-readout deficient proteins JF Kribelbauer, RE Loker, S Feng, C Rastogi, N Abe, HT Rube, ... Molecular cell 78 (1), 152-167. e11, 2020 | 30 | 2020 |
| 𝒩= 8 Supergravity 4-point amplitudes R Kallosh, CH Lee, T Rube Journal of High Energy Physics 2009 (02), 050, 2009 | 30 | 2009 |
| Categorical spectral analysis of periodicity in nucleosomal DNA H Jin, HT Rube, JS Song Nucleic acids research 44 (5), 2047-2057, 2016 | 24 | 2016 |
| Quantitative analysis and prediction of G-quadruplex forming sequences in double-stranded DNA M Kim, A Kreig, CY Lee, HT Rube, J Calvert, JS Song, S Myong Nucleic acids research 44 (10), 4807-4817, 2016 | 22 | 2016 |
| Transcription factor paralogs orchestrate alternative gene regulatory networks by context-dependent cooperation with multiple cofactors S Feng, C Rastogi, R Loker, WJ Glassford, H Tomas Rube, ... Nature Communications 13 (1), 3808, 2022 | 18 | 2022 |
| The effect of sequence mismatches on binding affinity and endonuclease activity are decoupled throughout the Cas9 binding site L Zhang, HT Rube, HJ Bussemaker, MA Pufall BioRxiv, 176255, 2017 | 13 | 2017 |
