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H. Tomas Rube
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The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer
RJA Bell, HT Rube, A Kreig, A Mancini, SD Fouse, RP Nagarajan, S Choi, ...
Science 348 (6238), 1036-1039, 2015
5652015
Understanding TERT promoter mutations: a common path to immortality
RJA Bell, HT Rube, A Xavier-Magalhães, BM Costa, A Mancini, JS Song, ...
Molecular Cancer Research 14 (4), 315-323, 2016
2852016
General inflaton potentials in supergravity
R Kallosh, A Linde, T Rube
Physical Review D 83 (4), 043507, 2011
2682011
Chaotic inflation and supersymmetry breaking
R Kallosh, A Linde, KA Olive, T Rube
Physical Review D 84 (8), 083519, 2011
1312011
Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape
JG Camp, CL Frank, CR Lickwar, H Guturu, T Rube, AM Wenger, J Chen, ...
Genome research 24 (9), 1504-1516, 2014
1302014
Accurate and sensitive quantification of protein-DNA binding affinity
C Rastogi, HT Rube, JF Kribelbauer, J Crocker, RE Loker, GD Martini, ...
Proceedings of the National Academy of Sciences 115 (16), E3692-E3701, 2018
972018
Measuring DNA mechanics on the genome scale
A Basu, DG Bobrovnikov, Z Qureshi, T Kayikcioglu, TTM Ngo, A Ranjan, ...
Nature 589 (7842), 462-467, 2021
942021
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines
L Zhang, JA Zuris, R Viswanathan, JN Edelstein, R Turk, B Thommandru, ...
Nature communications 12 (1), 3908, 2021
822021
Prediction of protein–ligand binding affinity from sequencing data with interpretable machine learning
HT Rube, C Rastogi, S Feng, JF Kribelbauer, A Li, B Becerra, LAN Melo, ...
Nature biotechnology 40 (10), 1520-1527, 2022
602022
Sequence features accurately predict genome-wide MeCP2 binding in vivo
HT Rube, W Lee, M Hejna, H Chen, DH Yasui, JF Hess, JM LaSalle, ...
Nature communications 7 (1), 11025, 2016
502016
A unified approach for quantifying and interpreting DNA shape readout by transcription factors
HT Rube, C Rastogi, JF Kribelbauer, HJ Bussemaker
Molecular systems biology 14 (2), e7902, 2018
402018
SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site
L Zhang, GD Martini, HT Rube, JF Kribelbauer, C Rastogi, VD FitzPatrick, ...
Genome research 28 (1), 111-121, 2018
382018
Nearly supersymmetric dark atoms
SR Behbahani, M Jankowiak, T Rube, JG Wacker
Advances in High Energy Physics 2011, 1-34, 2011
372011
Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes
L Zhang, HT Rube, CA Vakulskas, MA Behlke, HJ Bussemaker, MA Pufall
Nucleic acids research 48 (9), 5037-5053, 2020
342020
𝒩= 8 Supergravity 4-point amplitudes
R Kallosh, CH Lee, T Rube
Journal of High Energy Physics 2009 (02), 050, 2009
302009
Context-dependent gene regulation by homeodomain transcription factor complexes revealed by shape-readout deficient proteins
JF Kribelbauer, RE Loker, S Feng, C Rastogi, N Abe, HT Rube, ...
Molecular cell 78 (1), 152-167. e11, 2020
292020
Categorical spectral analysis of periodicity in nucleosomal DNA
H Jin, HT Rube, JS Song
Nucleic acids research 44 (5), 2047-2057, 2016
242016
Quantitative analysis and prediction of G-quadruplex forming sequences in double-stranded DNA
M Kim, A Kreig, CY Lee, HT Rube, J Calvert, JS Song, S Myong
Nucleic acids research 44 (10), 4807-4817, 2016
212016
Transcription factor paralogs orchestrate alternative gene regulatory networks by context-dependent cooperation with multiple cofactors
S Feng, C Rastogi, R Loker, WJ Glassford, H Tomas Rube, ...
Nature Communications 13 (1), 3808, 2022
182022
The effect of sequence mismatches on binding affinity and endonuclease activity are decoupled throughout the Cas9 binding site
L Zhang, HT Rube, HJ Bussemaker, MA Pufall
BioRxiv, 176255, 2017
132017
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Articles 1–20