| Hemophilia B gene therapy with a high-specific-activity factor IX variant LA George, SK Sullivan, A Giermasz, JEJ Rasko, BJ Samelson-Jones, ... New England Journal of Medicine 377 (23), 2215-2227, 2017 | 702 | 2017 |
| Targeted drug delivery to melanoma Q Liu, M Das, Y Liu, L Huang Advanced Drug Delivery Reviews 127, 208-221, 2018 | 128 | 2018 |
| Nanoformulated codelivery of quercetin and alantolactone promotes an antitumor response through synergistic immunogenic cell death for microsatellite-stable colorectal cancer J Zhang, L Shen, X Li, W Song, Y Liu, L Huang ACS nano 13 (11), 12511-12524, 2019 | 106 | 2019 |
| Nano-delivery of fraxinellone remodels tumor microenvironment and facilitates therapeutic vaccination in desmoplastic melanoma L Hou, Q Liu, L Shen, Y Liu, X Zhang, F Chen, L Huang Theranostics 8 (14), 3781, 2018 | 83 | 2018 |
| Modulation of tumor microenvironment for immunotherapy: focus on nanomaterial-based strategies Y Liu, J Guo, L Huang Theranostics 10 (7), 3099, 2020 | 80 | 2020 |
| Two nanoformulations induce reactive oxygen species and immunogenetic cell death for synergistic chemo-immunotherapy eradicating colorectal cancer and hepatocellular carcinoma J Guo, Z Yu, D Sun, Y Zou, Y Liu, L Huang Molecular Cancer 20, 1-17, 2021 | 77 | 2021 |
| Vasodilator hydralazine promotes nanoparticle penetration in advanced desmoplastic tumors Y Chen, W Song, L Shen, N Qiu, M Hu, Y Liu, Q Liu, L Huang ACS nano 13 (2), 1751-1763, 2019 | 70 | 2019 |
| BRAF peptide vaccine facilitates therapy of murine BRAF-mutant melanoma Q Liu, H Zhu, Y Liu, S Musetti, L Huang Cancer Immunology, Immunotherapy 67, 299-310, 2018 | 59 | 2018 |
| Multimodal therapy strategies based on hydrogels for the repair of spinal cord injury Y Wang, HQ Lv, X Chao, WX Xu, Y Liu, GX Ling, P Zhang Military Medical Research 9 (1), 16, 2022 | 50 | 2022 |
| Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy N Qiu, Y Liu, Q Liu, Y Chen, L Shen, M Hu, X Zhou, Y Shen, J Gao, ... Biomaterials 269, 120604, 2021 | 49 | 2021 |
| Nanocarrier-mediated immunogenic chemotherapy for triple negative breast cancer Y Liu, N Qiu, L Shen, Q Liu, J Zhang, YY Cheng, KH Lee, L Huang Journal of controlled release 323, 431-441, 2020 | 47 | 2020 |
| Nano delivery of simvastatin targets liver sinusoidal endothelial cells to remodel tumor microenvironment for hepatocellular carcinoma Z Yu, J Guo, Y Liu, M Wang, Z Liu, Y Gao, L Huang Journal of nanobiotechnology 20 (1), 9, 2022 | 45 | 2022 |
| Probing a dipeptide-based supramolecular assembly as an efficient camptothecin delivering carrier for cancer therapy: computational simulations and experimental validations M Sun, X Zhang, Z Gao, T Liu, C Luo, Y Zhao, Y Liu, Z He, J Wang, J Sun Nanoscale 11 (9), 3864-3876, 2019 | 42 | 2019 |
| Tumor-targeted gene therapy with lipid nanoparticles inhibits tumor-associated adipocytes and remodels the immunosuppressive tumor microenvironment in triple-negative breast cancer Y Liu, K Tiruthani, M Wang, X Zhou, N Qiu, Y Xiong, CV Pecot, R Liu, ... Nanoscale Horizons 6 (4), 319-329, 2021 | 41 | 2021 |
| Berberine Reverses Breast Cancer Multidrug Resistance Based on Fluorescence Pharmacokinetics In Vitro and In Vivo K Qian, C Tang, L Chen, S Zheng, Y Zhao, L Ma, L Xu, L Fan, J Yu, H Tan, ... ACS omega 6 (16), 10645-10654, 2021 | 28 | 2021 |
| Relaxin gene delivery modulates macrophages to resolve cancer fibrosis and synergizes with immune checkpoint blockade therapy X Zhou, Y Liu, M Hu, M Wang, X Liu, L Huang Science Advances 7 (8), eabb6596, 2021 | 24 | 2021 |
| Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses M Wang, B Rousseau, K Qiu, G Huang, Y Zhang, H Su, ... Nature Biotechnology, 1-12, 2023 | 15 | 2023 |
| Tumor neoantigen heterogeneity impacts bystander immune inhibition of pancreatic cancer growth M Das, X Zhou, Y Liu, A Das, BG Vincent, J Li, R Liu, L Huang Translational Oncology 13 (12), 100856, 2020 | 12 | 2020 |
| Oral metformin and polymetformin reprogram immunosuppressive microenvironment and boost immune checkpoint inhibitor therapy in colorectal cancer Y Xiong, W Song, L Shen, Y Wang, J Zhang, M Hu, Y Liu, J Li, S Musetti, ... Advanced Therapeutics 3 (12), 2000168, 2020 | 5 | 2020 |
| Development of a Minimal PBPK-QSP modeling platform for LNP-mRNA based therapeutics to study tissue disposition and protein expression dynamics K Miyazawa, Y Liu, H Bazzazi Frontiers in Nanotechnology 6, 1330406, 2024 | | 2024 |
Leaf HuangProfessor Emeritus, University of North Carolina at Chapel HillVerified email at email.unc.edu
