Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers H Kim, NP Nguyen, K Turner, S Wu, AD Gujar, J Luebeck, J Liu, ... Nature genetics 52 (9), 891-897, 2020 | 298 | 2020 |
Signal transducer and activator of transcription 3‐mediated CD133 up‐regulation contributes to promotion of hepatocellular carcinoma C Won, BH Kim, EH Yi, KJ Choi, EK Kim, JM Jeong, JH Lee, JJ Jang, ... Hepatology 62 (4), 1160-1173, 2015 | 185 | 2015 |
Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription Y Zhu, AD Gujar, CH Wong, H Tjong, CY Ngan, L Gong, YA Chen, H Kim, ... Cancer cell 39 (5), 694-707. e7, 2021 | 133 | 2021 |
Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response KC Johnson, KJ Anderson, ET Courtois, AD Gujar, FP Barthel, FS Varn, ... Nature genetics 53 (10), 1456-1468, 2021 | 125 | 2021 |
Ginsenoside 20 (S)-Rh2 exerts anti-cancer activity through targeting IL-6-induced JAK2/STAT3 pathway in human colorectal cancer cells S Han, AJ Jeong, H Yang, KB Kang, H Lee, EH Yi, BH Kim, CH Cho, ... Journal of ethnopharmacology 194, 83-90, 2016 | 93 | 2016 |
STAT3-RANTES autocrine signaling is essential for tamoxifen resistance in human breast cancer cells EH Yi, CS Lee, JK Lee, YJ Lee, MK Shin, CH Cho, KW Kang, JW Lee, ... Molecular Cancer Research 11 (1), 31-42, 2013 | 88 | 2013 |
Signal transducer and activator of transcription 3 as a therapeutic target for cancer and the tumor microenvironment BH Kim, EH Yi, SK Ye Archives of Pharmacal Research 39, 1085-1099, 2016 | 80 | 2016 |
Live-cell imaging shows uneven segregation of extrachromosomal DNA elements and transcriptionally active extrachromosomal DNA hubs in cancer E Yi, AD Gujar, M Guthrie, H Kim, D Zhao, KC Johnson, SB Amin, ... Cancer discovery 12 (2), 468-483, 2022 | 75 | 2022 |
Relative antioxidant activities of quercetin and its structurally related substances and their effects on NF-κB/CRE/AP-1 signaling in murine macrophages BH Kim, JS Choi, EH Yi, JK Lee, C Won, SK Ye, MH Kim Molecules and Cells 35, 410-420, 2013 | 67 | 2013 |
Dysfunction of microglial STAT3 alleviates depressive behavior via neuron–microglia interactions SH Kwon, JK Han, M Choi, YJ Kwon, SJ Kim, EH Yi, JC Shin, IH Cho, ... Neuropsychopharmacology 42 (10), 2072-2086, 2017 | 53 | 2017 |
Anti-dermatitis effects of oak wood vinegar on the DNCB-induced contact hypersensitivity via STAT3 suppression CS Lee, EH Yi, HR Kim, SR Huh, SH Sung, MH Chung, SK Ye Journal of ethnopharmacology 135 (3), 747-753, 2011 | 52 | 2011 |
Extrachromosomal DNA amplifications in cancer E Yi, R Chamorro González, AG Henssen, RGW Verhaak Nature Reviews Genetics 23 (12), 760-771, 2022 | 45 | 2022 |
BST-2 is a potential activator of invasion and migration in tamoxifen-resistant breast cancer cells EH Yi, H Yoo, KH Noh, S Han, H Lee, JK Lee, C Won, BH Kim, MH Kim, ... Biochemical and biophysical research communications 435 (4), 685-690, 2013 | 39 | 2013 |
Photoprotective potential of penta-O-galloyl-β-Dglucose by targeting NF-κB and MAPK signaling in UVB radiation-induced human dermal fibroblasts and mouse skin BH Kim, MS Choi, HG Lee, SH Lee, KH Noh, S Kwon, AJ Jeong, H Lee, ... Molecules and Cells 38 (11), 982-990, 2015 | 36 | 2015 |
Signal transducer and activator of transcription 3 (Stat3) contributes to T‐cell homeostasis by regulating pro‐survival Bcl‐2 family genes JK Lee, C Won, EH Yi, SH Seok, MH Kim, SJ Kim, MH Chung, HG Lee, ... Immunology 140 (3), 288-300, 2013 | 34 | 2013 |
Simvastatin suppresses RANTES-mediated neutrophilia in polyinosinic–polycytidylic acid-induced pneumonia CS Lee, EH Yi, JK Lee, C Won, YJ Lee, MK Shin, YM Yang, MH Chung, ... European Respiratory Journal 41 (5), 1147-1156, 2013 | 34 | 2013 |
Anti-cancer effect of doxorubicin is mediated by downregulation of HMG-Co A reductase via inhibition of EGFR/Src pathway UJ Yun, JH Lee, J Shim, K Yoon, SH Goh, EH Yi, SK Ye, JS Lee, H Lee, ... Laboratory Investigation 99 (8), 1157-1172, 2019 | 30 | 2019 |
Inhibition of double-stranded RNA-induced inducible nitric oxide synthase expression by fraxinellone and sauchinone in murine microglia CS Lee, C Won, H Yoo, EH Yi, Y Cho, JW Maeng, SH Sung, SK Ye, ... Biological and Pharmaceutical Bulletin 32 (11), 1870-1874, 2009 | 25 | 2009 |
Alleviation of collagen-induced arthritis by the benzoxathiole derivative BOT-4-one in mice: Implication of the Th1-and Th17-cell-mediated immune responses BH Kim, BR Yoon, EK Kim, KH Noh, SH Kwon, EH Yi, HG Lee, JS Choi, ... Biochemical Pharmacology 110, 47-57, 2016 | 16 | 2016 |
STAT3 potentiates SIAH-1 mediated proteasomal degradation of β-catenin in human embryonic kidney cells M Shin, EH Yi, BH Kim, JC Shin, JY Park, CH Cho, JW Park, KY Choi, ... Molecules and cells 39 (11), 821-826, 2016 | 12 | 2016 |