Follow
Tim Fenton
Tim Fenton
Associate Professor in Cancer Biology, University of Southampton
Verified email at soton.ac.uk
Title
Cited by
Cited by
Year
Malignant astrocytic glioma: genetics, biology, and paths to treatment
FB Furnari, T Fenton, RM Bachoo, A Mukasa, JM Stommel, A Stegh, ...
Genes & development 21 (21), 2683-2710, 2007
28772007
Functions and regulation of the 70 kDa ribosomal S6 kinases
TR Fenton, IT Gout
The international journal of biochemistry & cell biology 43 (1), 47-59, 2011
3952011
APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development
S Henderson, A Chakravarthy, X Su, C Boshoff, TR Fenton
Cell reports 7 (6), 1833-1841, 2014
3772014
HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management
M Lechner, J Liu, L Masterson, TR Fenton
Nature reviews Clinical oncology 19 (5), 306-327, 2022
3502022
Pan-cancer deconvolution of tumour composition using DNA methylation
A Chakravarthy, A Furness, K Joshi, E Ghorani, K Ford, MJ Ward, EV King, ...
Nature communications 9 (1), 3220, 2018
2512018
Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV-tumors
M Lechner, GM Frampton, T Fenton, A Feber, G Palmer, A Jay, N Pillay, ...
Genome medicine 5, 1-12, 2013
2422013
NOX4 inhibition potentiates immunotherapy by overcoming cancer-associated fibroblast-mediated CD8 T-cell exclusion from tumors
K Ford, CJ Hanley, M Mellone, C Szyndralewiez, F Heitz, P Wiesel, ...
Cancer research 80 (9), 1846-1860, 2020
2012020
Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation
K Salim, T Fenton, J Bacha, H Urien-Rodriguez, T Bonnert, HA Skynner, ...
Journal of Biological Chemistry 277 (18), 15482-15485, 2002
1602002
Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations
J Wykosky, T Fenton, F Furnari, WK Cavenee
Chinese journal of cancer 30 (1), 5, 2011
1592011
Using high-density DNA methylation arrays to profile copy number alterations
A Feber, P Guilhamon, M Lechner, T Fenton, GA Wilson, C Thirlwell, ...
Genome biology 15, 1-13, 2014
1512014
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma
M Lechner, T Fenton, J West, G Wilson, A Feber, S Henderson, C Thirlwell, ...
Genome medicine 5, 1-16, 2013
1472013
Activation of Rac1 by Src-dependent phosphorylation of Dock180Y1811 mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans
H Feng, B Hu, KW Liu, Y Li, X Lu, T Cheng, JJ Yiin, S Lu, S Keezer, ...
The Journal of clinical investigation 121 (12), 4670-4684, 2011
1332011
A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma
RD Read, TR Fenton, GG Gomez, J Wykosky, SR Vandenberg, I Babic, ...
PLoS genetics 9 (2), e1003253, 2013
1312013
Inhibition of nuclear PTEN tyrosine phosphorylation enhances glioma radiation sensitivity through attenuated DNA repair
J Ma, JA Benitez, J Li, S Miki, CP de Albuquerque, T Galatro, L Orellana, ...
Cancer cell 35 (3), 504-518. e7, 2019
1302019
APOBEC3 genes: retroviral restriction factors to cancer drivers
S Henderson, T Fenton
Trends in molecular medicine 21 (5), 274-284, 2015
1292015
Human papillomavirus drives tumor development throughout the head and neck: improved prognosis is associated with an immune response largely restricted to the oropharynx
A Chakravarthy, S Henderson, SM Thirdborough, CH Ottensmeier, X Su, ...
Journal of Clinical Oncology 34 (34), 4132, 2016
1262016
Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240
TR Fenton, D Nathanson, C Ponte de Albuquerque, D Kuga, A Iwanami, ...
Proceedings of the National Academy of Sciences 109 (35), 14164-14169, 2012
1232012
Large-scale profiling of kinase dependencies in cancer cell lines
J Campbell, CJ Ryan, R Brough, I Bajrami, HN Pemberton, IY Chong, ...
Cell reports 14 (10), 2490-2501, 2016
1182016
Protein kinase C phosphorylates ribosomal protein S6 kinase βII and regulates its subcellular localization
T Valovka, F Verdier, R Cramer, A Zhyvoloup, T Fenton, H Rebholz, ...
Molecular and cellular biology 23 (3), 852-863, 2003
1062003
A novel higher plant protein tyrosine phosphatase interacts with SNF1‐related protein kinases via a KIS (kinase interaction sequence) domain
AP Fordham‐Skelton, P Chilley, V Lumbreras, S Reignoux, TR Fenton, ...
The Plant Journal 29 (6), 705-715, 2002
1062002
The system can't perform the operation now. Try again later.
Articles 1–20