Obesity shapes metabolism in the tumor microenvironment to suppress anti-tumor immunity AE Ringel, JM Drijvers, GJ Baker, A Catozzi, JC García-Cañaveras, ... Cell 183 (7), 1848-1866. e26, 2020 | 399 | 2020 |
Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass JB Spinelli, H Yoon, AE Ringel, S Jeanfavre, CB Clish, MC Haigis Science 358 (6365), 941-946, 2017 | 359 | 2017 |
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate AA Chakraborty, T Laukka, M Myllykoski, AE Ringel, MA Booker, ... Science 363 (6432), 1217-1222, 2019 | 345 | 2019 |
Mitochondrial sirtuin network reveals dynamic SIRT3-dependent deacetylation in response to membrane depolarization W Yang, K Nagasawa, C Münch, Y Xu, K Satterstrom, S Jeong, SD Hayes, ... Cell 167 (4), 985-1000. e21, 2016 | 285 | 2016 |
Structural basis for histone H2B deubiquitination by the SAGA DUB module MT Morgan, M Haj-Yahya, AE Ringel, P Bandi, A Brik, C Wolberger Science 351 (6274), 725-728, 2016 | 244 | 2016 |
Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function G Notarangelo, JB Spinelli, EM Perez, GJ Baker, K Kurmi, I Elia, ... Science 377 (6614), 1519-1529, 2022 | 102 | 2022 |
A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation H Zhao, R Ghirlando, C Alfonso, F Arisaka, I Attali, DL Bain, MM Bakhtina, ... PloS one 10 (5), e0126420, 2015 | 95 | 2015 |
Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells JM Drijvers, JE Gillis, T Muijlwijk, TH Nguyen, EF Gaudiano, IS Harris, ... Cancer immunology research 9 (2), 184-199, 2021 | 92 | 2021 |
The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3 AM Cieniewicz, L Moreland, AE Ringel, SG Mackintosh, A Raman, ... Molecular & Cellular Proteomics 13 (11), 2896-2910, 2014 | 87 | 2014 |
A conserved asparagine has a structural role in ubiquitin-conjugating enzymes CE Berndsen, R Wiener, IW Yu, AE Ringel, C Wolberger Nature chemical biology 9 (3), 154-156, 2013 | 75 | 2013 |
Adaptation of human iPSC-derived cardiomyocytes to tyrosine kinase inhibitors reduces acute cardiotoxicity via metabolic reprogramming H Wang, RP Sheehan, AC Palmer, RA Everley, SA Boswell, N Ron-Harel, ... Cell systems 8 (5), 412-426. e7, 2019 | 59 | 2019 |
Yeast Tdh3 (glyceraldehyde 3-phosphate dehydrogenase) is a Sir2-interacting factor that regulates transcriptional silencing and rDNA recombination AE Ringel, R Ryznar, H Picariello, K Huang, AG Lazarus, SG Holmes PLOS genetics 9 (10), e1003871, 2013 | 59 | 2013 |
Structural basis for acyl-group discrimination by human Gcn5L2 AE Ringel, C Wolberger Acta Crystallographica Section D: Structural Biology 72 (7), 841-848, 2016 | 57 | 2016 |
Nucleosome competition reveals processive acetylation by the SAGA HAT module AE Ringel, AM Cieniewicz, SD Taverna, C Wolberger Proceedings of the National Academy of Sciences 112 (40), E5461-E5470, 2015 | 54 | 2015 |
Chemical and physiological features of mitochondrial acylation AE Ringel, SA Tucker, MC Haigis Molecular cell 72 (4), 610-624, 2018 | 39 | 2018 |
Small-molecule screen identifies de novo nucleotide synthesis as a vulnerability of cells lacking SIRT3 KNG Herrera, E Zaganjor, Y Ishikawa, JB Spinelli, H Yoon, JR Lin, ... Cell reports 22 (8), 1945-1955, 2018 | 34 | 2018 |
Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198 CM Guzzo, A Ringel, E Cox, I Uzoma, H Zhu, S Blackshaw, C Wolberger, ... PloS one 9 (8), e105271, 2014 | 33 | 2014 |
A role for intersubunit interactions in maintaining SAGA deubiquitinating module structure and activity NL Samara, AE Ringel, C Wolberger Structure 20 (8), 1414-1424, 2012 | 33 | 2012 |
Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway SE Smith, X Chen, LM Brier, JR Bumstead, NR Rensing, AE Ringel, ... Nature communications 11 (1), 6164, 2020 | 27 | 2020 |
Age-associated remodeling of T cell immunity and metabolism SJ Han, P Georgiev, AE Ringel, AH Sharpe, MC Haigis Cell metabolism 35 (1), 36-55, 2023 | 22 | 2023 |