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Vishal C. Kalel
Vishal C. Kalel
Verified email at ruhr-uni-bochum.de
Title
Cited by
Cited by
Year
Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites
M Dawidowski, L Emmanouilidis, VC Kalel, K Tripsianes, K Schorpp, ...
Science 355 (6332), 1416-1420, 2017
802017
Molecular basis of peroxisomal biogenesis disorders caused by defects in peroxisomal matrix protein import
S Nagotu, VC Kalel, R Erdmann, HW Platta
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (9 …, 2012
442012
Identification and functional characterization of Trypanosoma brucei peroxin 16
VC Kalel, W Schliebs, R Erdmann
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (10), 2326-2337, 2015
312015
COVID-19, neuropathology, and aging: SARS-CoV-2 neurological infection, mechanism, and associated complications
RS Kalra, JK Dhanjal, AS Meena, VC Kalel, S Dahiya, B Singh, ...
Frontiers in Aging Neuroscience 13, 662786, 2021
242021
Structure–Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14–PEX5 Protein–Protein Interaction with Trypanocidal Activity
M Dawidowski, VC Kalel, V Napolitano, R Fino, K Schorpp, ...
Journal of medicinal chemistry 63 (2), 847-879, 2019
212019
Evolutionary divergent PEX3 is essential for glycosome biogenesis and survival of trypanosomatid parasites
VC Kalel, M Li, S Gaussmann, F Delhommel, AB Schaefer, B Tippler, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1866 (12), 118520, 2019
192019
Unraveling of the structure and function of peroxisomal protein import machineries
VC Kalel, R Erdmann
Proteomics of Peroxisomes: Identifying Novel Functions and Regulatory …, 2018
182018
Come, sweet death: Targeting glycosomal protein import for antitrypanosomal drug development
VC Kalel, P Mäser, M Sattler, R Erdmann, GM Popowicz
Current opinion in microbiology 46, 116-122, 2018
152018
Inhibitors of glycosomal protein import provide new leads against trypanosomiasis
VC Kalel, L Emmanouilidis, M Dawidowski, W Schliebs, M Sattler, ...
Microbial Cell 4 (7), 229, 2017
142017
Structure-based design, synthesis and evaluation of a novel family of PEX5-PEX14 interaction inhibitors against Trypanosoma
V Napolitano, P Mróz, M Marciniak, VC Kalel, CA Softley, JDJ Olmos, ...
European Journal of Medicinal Chemistry 243, 114778, 2022
52022
Novel trypanocidal inhibitors that block glycosome biogenesis by targeting PEX3–PEX19 interaction
M Li, S Gaussmann, B Tippler, J Ott, GM Popowicz, W Schliebs, M Sattler, ...
Frontiers in Cell and Developmental Biology 9, 737159, 2021
52021
Current advances in the function and biogenesis of peroxisomes and their roles in health and disease
N Dahan, T Francisco, C Falter, T Rodrigues, V Kalel, M Kunze, T Hansen, ...
Histochemistry and cell biology 155, 513-524, 2021
52021
Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma
V Napolitano, CA Softley, A Blat, VC Kalel, K Schorpp, T Siebenmorgen, ...
Scientific Reports 12 (1), 14705, 2022
32022
Computer-aided design and synthesis of a new class of PEX14 inhibitors: substituted 2, 3, 4, 5-tetrahydrobenzo [F][1, 4] oxazepines as potential new trypanocidal agents
R Fino, D Lenhart, VC Kalel, CA Softley, V Napolitano, R Byrne, ...
Journal of Chemical Information and Modeling 61 (10), 5256-5268, 2021
32021
Development of novel PEX5-PEX14 protein-protein interaction (PPI) inhibitors based on an oxopiperazine template
M Marciniak, P Mróz, V Napolitano, VC Kalel, R Fino, E Pykacz, ...
European Journal of Medicinal Chemistry 258, 115587, 2023
22023
Isolation of Glycosomes from Trypanosoma brucei
CK Krishna, L Franke, R Erdmann, VC Kalel
Peroxisomes: Methods and protocols, 33-45, 2023
22023
Functional Analyses of a Putative, Membrane-Bound, Peroxisomal Protein Import Mechanism from the Apicomplexan Protozoan Toxoplasma gondii
AJ Mbekeani, WA Stanley, VC Kalel, N Dahan, E Zalckvar, L Sheiner, ...
Genes 9 (9), 434, 2018
22018
High confidence glycosomal membrane protein inventory unveils trypanosomal Peroxin PEX15
CK Krishna, H Das, L Hohnen, W Schliebs, S Oeljeklaus, B Warscheid, ...
bioRxiv, 2023.10. 13.562043, 2023
12023
Pyrazolopyridine derivatives and their use in therapy
M Sattler, G Popowicz, M Dawidowski, L Emmanouilidis, R Erdmann, ...
US Patent 10,138,242, 2018
12018
Pyrazolopyridine derivatives and their use in therapy
M Sattler, G Popowicz, M Dawidowski, L Emmanouilidis, R Erdmann, ...
US Patent 9,840,504, 2017
12017
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