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Kevin Frankowski
Kevin Frankowski
Assistant Professor of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy
Bestätigte E-Mail-Adresse bei unc.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Syntheses of the Stemona Alkaloids (±)-Stenine, (±)-Neostenine, and (±)-13-Epineostenine Using a Stereodivergent Diels–Alder/Azido-Schmidt Reaction
KJ Frankowski, JE Golden, Y Zeng, Y Lei, J Aubé
Journal of the American Chemical Society 130 (18), 6018-6024, 2008
1562008
Development of functionally selective, small molecule agonists at kappa opioid receptors
L Zhou, KM Lovell, KJ Frankowski, SR Slauson, AM Phillips, JM Streicher, ...
Journal of Biological Chemistry 288 (51), 36703-36716, 2013
1542013
Structure–activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase
TF Chou, K Li, KJ Frankowski, FJ Schoenen, RJ Deshaies
ChemMedChem 8 (2), 297-312, 2013
1482013
Grubbs' catalyst in paraffin: An air-stable preparation for alkene metathesis
DF Taber, KJ Frankowski
The Journal of organic chemistry 68 (15), 6047-6048, 2003
1062003
Practical electrochemical anodic oxidation of polycyclic lactams for late stage functionalization
KJ Frankowski, R Liu, GL Milligan, KD Moeller, J Aubé
Angewandte Chemie International Edition 54 (36), 10555-10558, 2015
872015
Optimization of potent hepatitis C virus NS3 helicase inhibitors isolated from the yellow dyes thioflavine S and primuline
K Li, KJ Frankowski, CA Belon, B Neuenswander, J Ndjomou, AM Hanson, ...
Journal of medicinal chemistry 55 (7), 3319-3330, 2012
742012
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis
KJ Frankowski, C Wang, S Patnaik, FJ Schoenen, N Southall, D Li, ...
Science translational medicine 10 (441), eaap8307, 2018
682018
Chemotype-selective modes of action of κ-opioid receptor agonists
E Vardy, PD Mosier, KJ Frankowski, H Wu, V Katritch, RB Westkaemper, ...
Journal of Biological Chemistry 288 (48), 34470-34483, 2013
682013
structure–activity relationship studies of functionally selective kappa opioid receptor agonists that modulate ERK 1/2 phosphorylation while preserving G protein over …
KM Lovell, KJ Frankowski, EL Stahl, SR Slauson, E Yoo, TE Prisinzano, ...
ACS chemical neuroscience 6 (8), 1411-1419, 2015
612015
Benzothiazole and pyrrolone flavivirus inhibitors targeting the viral helicase
NL Sweeney, AM Hanson, S Mukherjee, J Ndjomou, BJ Geiss, JJ Steel, ...
ACS infectious diseases 1 (3), 140-148, 2015
592015
A multicenter study investigating SARS-CoV-2 in tertiary-care hospital wastewater. viral burden correlates with increasing hospitalized cases as well as hospital-associated …
N Acosta, MA Bautista, J Hollman, J McCalder, AB Beaudet, L Man, ...
Water Research 201, 117369, 2021
582021
Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays
S Mukherjee, AM Hanson, WR Shadrick, J Ndjomou, NL Sweeney, ...
Nucleic Acids Research 40 (17), 8607-8621, 2012
562012
Discovery of small molecule kappa opioid receptor agonist and antagonist chemotypes through a HTS and hit refinement strategy
KJ Frankowski, MP Hedrick, P Gosalia, K Li, S Shi, D Whipple, P Ghosh, ...
ACS chemical neuroscience 3 (3), 221-236, 2012
532012
Grubbs's cross metathesis of eugenol with cis-2-butene-1, 4-diol to make a natural product. An organometallic experiment for the undergraduate lab
DF Taber, KJ Frankowski
Journal of chemical education 83 (2), 283, 2006
482006
Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus
J Morgenweck, KJ Frankowski, TE Prisinzano, J Aubé, LM Bohn
Neuropharmacology 99, 600-609, 2015
472015
Efficient synthesis of γ-lactams by a tandem reductive amination/lactamization sequence
J Nöth, KJ Frankowski, B Neuenswander, J Aubé, O Reiser
Journal of combinatorial chemistry 10 (3), 456-459, 2008
442008
Synthesis and receptor profiling of Stemona alkaloid analogues reveal a potent class of sigma ligands
KJ Frankowski, V Setola, JM Evans, B Neuenswander, BL Roth, J Aubé
Proceedings of the National Academy of Sciences 108 (17), 6727-6732, 2011
432011
Synthesis of (+)-sulcatine G
DF Taber, KJ Frankowski
The Journal of Organic Chemistry 70 (16), 6417-6421, 2005
422005
Longitudinal SARS-CoV-2 RNA wastewater monitoring across a range of scales correlates with total and regional COVID-19 burden in a well-defined urban population
N Acosta, MA Bautista, BJ Waddell, J McCalder, AB Beaudet, L Man, ...
Water Research 220, 118611, 2022
402022
Identification of positive allosteric modulators of the D1 dopamine receptor that act at diverse binding sites
KD Luderman, JL Conroy, RB Free, N Southall, M Ferrer, M Sanchez-Soto, ...
Molecular Pharmacology 94 (4), 1197-1209, 2018
382018
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