Syntheses of the Stemona Alkaloids (±)-Stenine, (±)-Neostenine, and (±)-13-Epineostenine Using a Stereodivergent Diels–Alder/Azido-Schmidt Reaction KJ Frankowski, JE Golden, Y Zeng, Y Lei, J Aubé Journal of the American Chemical Society 130 (18), 6018-6024, 2008 | 156 | 2008 |
Development of functionally selective, small molecule agonists at kappa opioid receptors L Zhou, KM Lovell, KJ Frankowski, SR Slauson, AM Phillips, JM Streicher, ... Journal of Biological Chemistry 288 (51), 36703-36716, 2013 | 154 | 2013 |
Structure–activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase TF Chou, K Li, KJ Frankowski, FJ Schoenen, RJ Deshaies ChemMedChem 8 (2), 297-312, 2013 | 148 | 2013 |
Grubbs' catalyst in paraffin: An air-stable preparation for alkene metathesis DF Taber, KJ Frankowski The Journal of organic chemistry 68 (15), 6047-6048, 2003 | 106 | 2003 |
Practical electrochemical anodic oxidation of polycyclic lactams for late stage functionalization KJ Frankowski, R Liu, GL Milligan, KD Moeller, J Aubé Angewandte Chemie International Edition 54 (36), 10555-10558, 2015 | 87 | 2015 |
Optimization of potent hepatitis C virus NS3 helicase inhibitors isolated from the yellow dyes thioflavine S and primuline K Li, KJ Frankowski, CA Belon, B Neuenswander, J Ndjomou, AM Hanson, ... Journal of medicinal chemistry 55 (7), 3319-3330, 2012 | 74 | 2012 |
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis KJ Frankowski, C Wang, S Patnaik, FJ Schoenen, N Southall, D Li, ... Science translational medicine 10 (441), eaap8307, 2018 | 68 | 2018 |
Chemotype-selective modes of action of κ-opioid receptor agonists E Vardy, PD Mosier, KJ Frankowski, H Wu, V Katritch, RB Westkaemper, ... Journal of Biological Chemistry 288 (48), 34470-34483, 2013 | 68 | 2013 |
structure–activity relationship studies of functionally selective kappa opioid receptor agonists that modulate ERK 1/2 phosphorylation while preserving G protein over … KM Lovell, KJ Frankowski, EL Stahl, SR Slauson, E Yoo, TE Prisinzano, ... ACS chemical neuroscience 6 (8), 1411-1419, 2015 | 61 | 2015 |
Benzothiazole and pyrrolone flavivirus inhibitors targeting the viral helicase NL Sweeney, AM Hanson, S Mukherjee, J Ndjomou, BJ Geiss, JJ Steel, ... ACS infectious diseases 1 (3), 140-148, 2015 | 59 | 2015 |
A multicenter study investigating SARS-CoV-2 in tertiary-care hospital wastewater. viral burden correlates with increasing hospitalized cases as well as hospital-associated … N Acosta, MA Bautista, J Hollman, J McCalder, AB Beaudet, L Man, ... Water Research 201, 117369, 2021 | 58 | 2021 |
Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays S Mukherjee, AM Hanson, WR Shadrick, J Ndjomou, NL Sweeney, ... Nucleic Acids Research 40 (17), 8607-8621, 2012 | 56 | 2012 |
Discovery of small molecule kappa opioid receptor agonist and antagonist chemotypes through a HTS and hit refinement strategy KJ Frankowski, MP Hedrick, P Gosalia, K Li, S Shi, D Whipple, P Ghosh, ... ACS chemical neuroscience 3 (3), 221-236, 2012 | 53 | 2012 |
Grubbs's cross metathesis of eugenol with cis-2-butene-1, 4-diol to make a natural product. An organometallic experiment for the undergraduate lab DF Taber, KJ Frankowski Journal of chemical education 83 (2), 283, 2006 | 48 | 2006 |
Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus J Morgenweck, KJ Frankowski, TE Prisinzano, J Aubé, LM Bohn Neuropharmacology 99, 600-609, 2015 | 47 | 2015 |
Efficient synthesis of γ-lactams by a tandem reductive amination/lactamization sequence J Nöth, KJ Frankowski, B Neuenswander, J Aubé, O Reiser Journal of combinatorial chemistry 10 (3), 456-459, 2008 | 44 | 2008 |
Synthesis and receptor profiling of Stemona alkaloid analogues reveal a potent class of sigma ligands KJ Frankowski, V Setola, JM Evans, B Neuenswander, BL Roth, J Aubé Proceedings of the National Academy of Sciences 108 (17), 6727-6732, 2011 | 43 | 2011 |
Synthesis of (+)-sulcatine G DF Taber, KJ Frankowski The Journal of Organic Chemistry 70 (16), 6417-6421, 2005 | 42 | 2005 |
Longitudinal SARS-CoV-2 RNA wastewater monitoring across a range of scales correlates with total and regional COVID-19 burden in a well-defined urban population N Acosta, MA Bautista, BJ Waddell, J McCalder, AB Beaudet, L Man, ... Water Research 220, 118611, 2022 | 40 | 2022 |
Identification of positive allosteric modulators of the D1 dopamine receptor that act at diverse binding sites KD Luderman, JL Conroy, RB Free, N Southall, M Ferrer, M Sanchez-Soto, ... Molecular Pharmacology 94 (4), 1197-1209, 2018 | 38 | 2018 |