| Phenalenone-type phytoalexins mediate resistance of banana plants (Musa spp.) to the burrowing nematode Radopholus similis D Hölscher, S Dhakshinamoorthy, T Alexandrov, M Becker, ... Proceedings of the National Academy of Sciences 111 (1), 105-110, 2014 | 153 | 2014 |
| Vinylogous chain branching catalysed by a dedicated polyketide synthase module T Bretschneider, JB Heim, D Heine, R Winkler, B Busch, B Kusebauch, ... Nature 502 (7469), 124-128, 2013 | 129 | 2013 |
| Imaging mass spectrometry and genome mining reveal highly antifungal virulence factor of mushroom soft rot pathogen K Graupner, K Scherlach, T Bretschneider, G Lackner, M Roth, H Gross, ... Angewandte Chemie International Edition 51 (52), 13173-13177, 2012 | 76 | 2012 |
| A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis T Bretschneider, G Zocher, M Unger, K Scherlach, T Stehle, C Hertweck Nature Chemical Biology 8 (2), 154-161, 2012 | 70 | 2012 |
| Automated MALDI target preparation concept: providing ultra-high-throughput mass spectrometry–based screening for drug discovery M Winter, R Ries, C Kleiner, D Bischoff, AH Luippold, T Bretschneider, ... SLAS TECHNOLOGY: Translating Life Sciences Innovation 24 (2), 209-221, 2019 | 66 | 2019 |
| Synthetic remodeling of the chartreusin pathway to tune antiproliferative and antibacterial activities N Ueberschaar, Z Xu, K Scherlach, M Metsa-Ketela, T Bretschneider, ... Journal of the American Chemical Society 135 (46), 17408-17416, 2013 | 52 | 2013 |
| RapidFire BLAZE-mode is boosting ESI-MS toward high-throughput-screening T Bretschneider, C Ozbal, M Holstein, M Winter, FH Buettner, S Thamm, ... SLAS TECHNOLOGY: Translating Life Sciences Innovation 24 (4), 386-393, 2019 | 51 | 2019 |
| FKBP51 modulates steroid sensitivity and NFκB signalling: a novel anti‐inflammatory drug target M Kästle, B Kistler, T Lamla, T Bretschneider, D Lamb, P Nicklin, D Wyatt European journal of immunology 48 (11), 1904-1914, 2018 | 45 | 2018 |
| MALDI-TOF mass spectrometry-based high-throughput screening for inhibitors of the cytosolic DNA sensor cGAS RP Simon, M Winter, C Kleiner, R Ries, G Schnapp, A Heimann, J Li, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (4), 372-383, 2020 | 44 | 2020 |
| Establishing MALDI-TOF as versatile drug discovery readout to dissect the PTP1B enzymatic reaction M Winter, T Bretschneider, C Kleiner, R Ries, JP Hehn, N Redemann, ... SLAS DISCOVERY: Advancing Life Sciences R&D 23 (6), 561-573, 2018 | 44 | 2018 |
| Biosynthesis and mass spectrometric imaging of tolaasin, the virulence factor of brown blotch mushroom disease K Scherlach, G Lackner, K Graupner, S Pidot, T Bretschneider, ... ChemBioChem 14 (18), 2439-2443, 2013 | 38 | 2013 |
| Human lung fibroblast-to-myofibroblast transformation is not driven by an LDH5-dependent metabolic shift towards aerobic glycolysis E Schruf, V Schroeder, CA Kuttruff, S Weigle, M Krell, M Benz, ... Respiratory research 20, 1-10, 2019 | 37 | 2019 |
| Discovery of BI-2545: A novel autotaxin inhibitor that significantly reduces LPA levels in vivo CA Kuttruff, M Ferrara, T Bretschneider, S Hoerer, S Handschuh, B Nosse, ... ACS Medicinal Chemistry Letters 8 (12), 1252-1257, 2017 | 37 | 2017 |
| Enzymatic polyketide chain branching to give substituted lactone, lactam, and glutarimide heterocycles D Heine, T Bretschneider, S Sundaram, C Hertweck Angewandte Chemie International Edition 53 (43), 11645-11649, 2014 | 35 | 2014 |
| Rational design of an apoptosis-inducing photoreactive DNA intercalator N Ueberschaar, HM Dahse, T Bretschneider, C Hertweck Angew. Chem. Int. Ed 52, 6185-6189, 2013 | 30 | 2013 |
| Biomarker discovery for chronic liver diseases by multi-omics–a preclinical case study D Veyel, K Wenger, A Broermann, T Bretschneider, AH Luippold, ... Scientific reports 10 (1), 1314, 2020 | 27 | 2020 |
| Biomarker candidates for the detection of an infectious etiology of febrile neutropenia ME Richter, S Neugebauer, F Engelmann, S Hagel, K Ludewig, ... Infection 44, 175-186, 2016 | 27 | 2016 |
| Activation of the kynurenine pathway and mitochondrial respiration to face allostatic load in a double-hit model of stress V Nold, C Sweatman, A Karabatsiakis, C Boeck, T Bretschneider, ... Psychoneuroendocrinology 107, 148-159, 2019 | 26 | 2019 |
| MALDI-TOF-based affinity selection mass spectrometry for automated screening of protein–ligand interactions at high throughput RP Simon, M Winter, C Kleiner, L Wehrle, M Karnath, R Ries, M Zeeb, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (1), 44-57, 2021 | 21 | 2021 |
| Ultrafast and predictive mass spectrometry–based autotaxin assays for label-free potency screening T Bretschneider, AH Luippold, H Romig, D Bischoff, K Klinder, P Nicklin, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (4), 425-432, 2017 | 20 | 2017 |
