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Yu-Chen Lo
Yu-Chen Lo
Research Scientist, Stanford University
Verified email at stanford.edu - Homepage
Title
Cited by
Cited by
Year
Machine learning in chemoinformatics and drug discovery
YC Lo, SE Rensi, W Torng, RB Altman
Drug discovery today 23 (8), 1538-1546, 2018
8612018
The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly
JZ Torres, MK Summers, D Peterson, MJ Brauer, J Lee, S Senese, ...
Cell 147 (6), 1309-1323, 2011
932011
Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens
YC Lo, S Senese, CM Li, Q Hu, Y Huang, R Damoiseaux, JZ Torres
PLoS computational biology 11 (3), e1004153, 2015
742015
Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development
S Senese, YC Lo, D Huang, TA Zangle, AA Gholkar, L Robert, B Homet, ...
Cell death & disease 5 (10), e1462-e1462, 2014
662014
Fatostatin inhibits cancer cell proliferation by affecting mitotic microtubule spindle assembly and cell division
AA Gholkar, K Cheung, KJ Williams, YC Lo, SA Hamideh, C Nnebe, ...
Journal of Biological Chemistry 291 (33), 17001-17008, 2016
572016
3D chemical similarity networks for structure-based target prediction and scaffold hopping
YC Lo, S Senese, R Damoiseaux, JZ Torres
ACS chemical biology 11 (8), 2244-2253, 2016
532016
Homology modeling of TMPRSS2 yields candidate drugs that may inhibit entry of SARS-CoV-2 into human cells.
S Rensi, A Keys, YC Lo, A Derry, G McInnes, T Liu, R Altman
ChemRxiv, 2020
462020
The X-linked-intellectual-disability-associated ubiquitin ligase Mid2 interacts with astrin and regulates astrin levels to promote cell division
AA Gholkar, S Senese, YC Lo, E Vides, E Contreras, E Hodara, J Capri, ...
Cell reports 14 (2), 180-188, 2016
362016
Computational cell cycle profiling of cancer cells for prioritizing FDA-approved drugs with repurposing potential
YC Lo, S Senese, B France, AA Gholkar, R Damoiseaux, JZ Torres
Scientific reports 7 (1), 11261, 2017
332017
Computational analysis of kinase inhibitor selectivity using structural knowledge
YC Lo, T Liu, KM Morrissey, S Kakiuchi-Kiyota, AR Johnson, F Broccatelli, ...
Bioinformatics 35 (2), 235-242, 2019
272019
Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site
YC Lo, O Cormier, T Liu, KW Nettles, JA Katzenellenbogen, T Stearns, ...
Nature communications 10 (1), 1033, 2019
262019
Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis
AA Gholkar, S Senese, YC Lo, J Capri, WJ Deardorff, H Dharmarajan, ...
Cell Cycle 14 (7), 1116-1125, 2015
252015
A unique insertion in STARD9's motor domain regulates its stability
S Senese, K Cheung, YC Lo, AA Gholkar, X Xia, JA Wohlschlegel, ...
Molecular biology of the cell 26 (3), 440-452, 2015
232015
A cancer biologist's primer on machine learning applications in high‐dimensional cytometry
TJ Keyes, P Domizi, YC Lo, GP Nolan, KL Davis
Cytometry Part A 97 (8), 782-799, 2020
222020
Chemical similarity networks for drug discovery
YC Lo, JZ Torres
Special Topics in Drug Discovery 1, 53-70, 2016
132016
Artificial intelligence-based drug design and discovery
YC Lo, G Ren, H Honda, KL Davis
Cheminformatics and its applications, 2019
112019
CytofIn enables integrated analysis of public mass cytometry datasets using generalized anchors
YC Lo, TJ Keyes, A Jager, J Sarno, P Domizi, R Majeti, KM Sakamoto, ...
Nature Communications 13 (1), 934, 2022
92022
Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation
S Senese, YC Lo, AA Gholkar, CM Li, Y Huang, J Mottahedeh, ...
Oncotarget 8 (61), 104007, 2017
82017
Single-cell technologies uncover intra-tumor heterogeneity in childhood cancers
YC Lo, Y Liu, M Kammersgaard, A Koladiya, TJ Keyes, KL Davis
Seminars in Immunopathology 45 (1), 61-69, 2023
32023
Regulation of iron homeostasis through Parkin-mediated lactoferrin ubiquitylation
AA Gholkar, S Schmollinger, EF Velasquez, YC Lo, W Cohn, J Capri, ...
Biochemistry 59 (32), 2916-2921, 2020
32020
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