| High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9 GK Varshney, W Pei, MC LaFave, J Idol, L Xu, V Gallardo, B Carrington, ... Genome research 25 (7), 1030-1042, 2015 | 547 | 2015 |
| Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy RJ Chandler, MC LaFave, GK Varshney, NS Trivedi, N Carrillo-Carrasco, ... The Journal of clinical investigation 125 (2), 870-880, 2015 | 372 | 2015 |
| Phylogenetic distribution of CRISPR-Cas systems in antibiotic-resistant Pseudomonas aeruginosa A van Belkum, LB Soriaga, MC LaFave, S Akella, JB Veyrieras, EM Barbu, ... MBio 6 (6), 10.1128/mbio. 01796-15, 2015 | 202 | 2015 |
| A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish GK Varshney, B Carrington, W Pei, K Bishop, Z Chen, C Fan, L Xu, ... Nature protocols 11 (12), 2357-2375, 2016 | 195 | 2016 |
| Multiplex conditional mutagenesis using transgenic expression of Cas9 and sgRNAs L Yin, LA Maddison, M Li, N Kara, MC LaFave, GK Varshney, SM Burgess, ... Genetics 200 (2), 431-441, 2015 | 170 | 2015 |
| A 3D searchable database of transgenic zebrafish Gal4 and Cre lines for functional neuroanatomy studies GD Marquart, KM Tabor, M Brown, JL Strykowski, GK Varshney, ... Frontiers in neural circuits 9, 78, 2015 | 133 | 2015 |
| MLV integration site selection is driven by strong enhancers and active promoters MC LaFave, GK Varshney, DE Gildea, TG Wolfsberg, AD Baxevanis, ... Nucleic Acids Research 42 (7), 4257-4269, 2014 | 112 | 2014 |
| A defined zebrafish line for high-throughput genetics and genomics: NHGRI-1 MC LaFave, GK Varshney, M Vemulapalli, JC Mullikin, SM Burgess Genetics 198 (1), 167-170, 2014 | 93 | 2014 |
| Long-term correction of Sandhoff disease following intravenous delivery of rAAV9 to mouse neonates JS Walia, N Altaleb, A Bello, C Kruck, MC LaFave, GK Varshney, ... Molecular Therapy 23 (3), 414-422, 2015 | 90 | 2015 |
| Mitotic recombination: why? when? how? where? MC LaFave, J Sekelsky PLoS genetics 5 (3), e1000411, 2009 | 66 | 2009 |
| Genotoxicity in mice following AAV gene delivery: a safety concern for human gene therapy? RJ Chandler, MC LaFave, GK Varshney, SM Burgess, CP Venditti Molecular Therapy 24 (2), 198-201, 2016 | 61 | 2016 |
| Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters CT Burket, JE Montgomery, R Thummel, SC Kassen, MC LaFave, ... Transgenic research 17, 265-279, 2008 | 60 | 2008 |
| Deep semantic protein representation for annotation, discovery, and engineering AS Schwartz, GJ Hannum, ZR Dwiel, ME Smoot, AR Grant, JM Knight, ... BioRxiv, 365965, 2018 | 23 | 2018 |
| Genome-wide analysis of transposon and retroviral insertions reveals preferential integrations in regions of DNA flexibility P Vrljicak, S Tao, GK Varshney, HNB Quach, A Joshi, MC LaFave, ... G3: Genes, Genomes, Genetics 6 (4), 805-817, 2016 | 22 | 2016 |
| Phylogenetic distribution of CRISPR-Cas systems in antibiotic-resistant Pseudomonas aeruginosa. mBio 6: e01796-15 A van Belkum, LB Soriaga, MC LaFave, S Akella, JB Veyrieras, EM Barbu, ... November, 2015 | 20 | 2015 |
| Sources and Structures of Mitotic Crossovers That Arise When BLM Helicase Is Absent in Drosophila MC LaFave, SL Andersen, EP Stoffregen, J Korda Holsclaw, KP Kohl, ... Genetics 196 (1), 107-118, 2014 | 19 | 2014 |
| A multifunctional mutagenesis system for analysis of gene function in zebrafish HNB Quach, S Tao, P Vrljicak, A Joshi, H Ruan, R Sukumaran, ... G3: Genes, Genomes, Genetics 5 (6), 1283-1299, 2015 | 18 | 2015 |
| Transcription Initiation From Within P Elements Generates Hypomorphic Mutations in Drosophila melanogaster MC LaFave, J Sekelsky Genetics 188 (3), 749-752, 2011 | 18 | 2011 |
| Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish C Seiler, N Gebhart, Y Zhang, SA Shinton, Y Li, NL Ross, X Liu, Q Li, ... PLoS One 10 (7), e0131908, 2015 | 16 | 2015 |
| DNA damage responses in Drosophila nbs mutants with reduced or altered NBS function S Mukherjee, MC LaFave, J Sekelsky DNA repair 8 (7), 803-812, 2009 | 10 | 2009 |
Shawn M BurgessNational Human Genome Research InstituteVerified email at mail.nih.gov
