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Alicia Solorzano
Alicia Solorzano
Director, Viral Vaccines, Pfizer
Verified email at pfizer.com
Title
Cited by
Cited by
Year
Characterization of the reconstructed 1918 Spanish influenza pandemic virus
TM Tumpey, CF Basler, PV Aguilar, H Zeng, A Solórzano, DE Swayne, ...
science 310 (5745), 77-80, 2005
18292005
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission
TM Tumpey, TR Maines, N Van Hoeven, L Glaser, A Solórzano, C Pappas, ...
Science 315 (5812), 655-659, 2007
6882007
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality …
TM Tumpey, A García-Sastre, JK Taubenberger, P Palese, DE Swayne, ...
Journal of virology 79 (23), 14933-14944, 2005
6612005
Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs
A Solórzano, RJ Webby, KM Lager, BH Janke, A García-Sastre, JA Richt
Journal of virology 79 (12), 7535-7543, 2005
3222005
Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza
J Steel, AC Lowen, L Pena, M Angel, A Solórzano, R Albrecht, DR Perez, ...
Journal of virology 83 (4), 1742-1753, 2009
2872009
Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene
D Grimm, P Staeheli, M Hufbauer, I Koerner, L Martínez-Sobrido, ...
Proceedings of the National Academy of Sciences 104 (16), 6806-6811, 2007
2502007
A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial
R Nachbagauer, J Feser, A Naficy, DI Bernstein, J Guptill, EB Walter, ...
Nature medicine 27 (1), 106-114, 2021
2362021
Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine
JA Richt, P Lekcharoensuk, KM Lager, AL Vincent, CM Loiacono, ...
Journal of virology 80 (22), 11009-11018, 2006
2212006
Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus
C Pappas, PV Aguilar, CF Basler, A Solórzano, H Zeng, LA Perrone, ...
Proceedings of the National Academy of Sciences 105 (8), 3064-3069, 2008
2102008
Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility
R Hai, M Schmolke, VH Leyva-Grado, RR Thangavel, I Margine, EL Jaffe, ...
Nature communications 4 (1), 2854, 2013
1812013
Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial
DI Bernstein, J Guptill, A Naficy, R Nachbagauer, F Berlanda-Scorza, ...
The lancet infectious diseases 20 (1), 80-91, 2020
1282020
A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies
R Nachbagauer, WC Liu, A Choi, TJ Wohlbold, T Atlas, M Rajendran, ...
npj Vaccines 2 (1), 26, 2017
1272017
Hemagglutinin (HA) proteins from H1 and H3 serotypes of influenza A viruses require different antigen designs for the induction of optimal protective antibody responses as …
S Wang, J Taaffe, C Parker, A Solórzano, H Cao, A García-Sastre, S Lu
Journal of virology 80 (23), 11628-11637, 2006
1252006
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
K Leppek, GW Byeon, W Kladwang, HK Wayment-Steele, CH Kerr, AF Xu, ...
Nature communications 13 (1), 1536, 2022
1192022
Heterologous HA DNA vaccine prime—inactivated influenza vaccine boost is more effective than using DNA or inactivated vaccine alone in eliciting antibody responses against H1 …
S Wang, C Parker, J Taaffe, A Solórzano, A García-Sastre, S Lu
Vaccine 26 (29-30), 3626-3633, 2008
1132008
Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus
CR Baskin, H Bielefeldt-Ohmann, A Garcia-Sastre, TM Tumpey, ...
Journal of virology 81 (21), 11817-11827, 2007
1022007
Viral reassortment and transmission after co-infection of pigs with classical H1N1 and triple-reassortant H3N2 swine influenza viruses
W Ma, KM Lager, P Lekcharoensuk, ES Ulery, BH Janke, A Solorzano, ...
Journal of General Virology 91 (9), 2314-2321, 2010
702010
Alternative live-attenuated influenza vaccines based on modifications in the polymerase genes protect against epidemic and pandemic flu
A Solórzano, J Ye, DR Pérez
Journal of virology 84 (9), 4587-4596, 2010
682010
Sequential immunization with live-attenuated chimeric hemagglutinin-based vaccines confers heterosubtypic immunity against influenza A viruses in a preclinical ferret model
WC Liu, R Nachbagauer, D Stadlbauer, A Solórzano, F Berlanda-Scorza, ...
Frontiers in immunology 10, 450546, 2019
552019
An avian live attenuated master backbone for potential use in epidemic and pandemic influenza vaccines
D Hickman, MJ Hossain, H Song, Y Araya, A Solorzano, DR Perez
Journal of general virology 89 (11), 2682-2690, 2008
542008
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