Identification of the α2-δ-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin MJ Field, PJ Cox, E Stott, H Melrose, J Offord, TZ Su, S Bramwell, ... Proceedings of the National Academy of Sciences 103 (46), 17537-17542, 2006 | 665 | 2006 |
Gabapentin (neurontin) and S‐(+)‐3‐isobutylgaba represent a novel class of selective antihyperalgesic agents MJ Field, RJ Oles, AS Lewis, S McCleary, J Hughes, L Singh British journal of pharmacology 121 (8), 1513-1522, 1997 | 420 | 1997 |
Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat MJ Field, S McCleary, J Hughes, L Singh Pain 80 (1-2), 391-398, 1999 | 362 | 1999 |
Evaluation of gabapentin and S-(+)-3-isobutylgaba in a rat model of postoperative pain MJ Field, EF Holloman, S McCleary, J Hughes, L Singh Journal of Pharmacology and Experimental therapeutics 282 (3), 1242-1246, 1997 | 313 | 1997 |
The monosodium iodoacetate model of osteoarthritis: a model of chronic nociceptive pain in rats? R Combe, S Bramwell, MJ Field Neuroscience letters 370 (2-3), 236-240, 2004 | 303 | 2004 |
Structure−Activity Relationships of Pregabalin and Analogues That Target the α2-δ Protein TR Belliotti, T Capiris, IV Ekhato, JJ Kinsora, MJ Field, TG Heffner, ... Journal of medicinal chemistry 48 (7), 2294-2307, 2005 | 286 | 2005 |
The antiepileptic agent gabapentin (Neurontin) possesses anxiolytic-like and antinociceptive actions that are reversed byd-serine L Singh, MJ Field, P Ferris, JC Hunter, RJ Oles, RG Williams, ... Psychopharmacology 127, 1-9, 1996 | 286 | 1996 |
Detection of static and dynamic components of mechanical allodynia in rat models of neuropathic pain: are they signalled by distinct primary sensory neurones? MJ Field, S Bramwell, J Hughes, L Singh Pain 83 (2), 303-311, 1999 | 250 | 1999 |
Evidence for an involvement of the brain cholecystokinin B receptor in anxiety. L Singh, AS Lewis, MJ Field, J Hughes, GN Woodruff Proceedings of the National Academy of Sciences 88 (4), 1130-1133, 1991 | 248 | 1991 |
Further evidence for the role of the α2δ subunit of voltage dependent calcium channels in models of neuropathic pain MJ Field, J Hughes, L Singh British journal of pharmacology 131 (2), 282-286, 2000 | 160 | 2000 |
The behavioural properties of CI‐988, a selective cholecystokininB receptor antagonist L Singh, MJ Field, J Hughes, R Menzies, RJ Oles, CA Vass, GN Woodruff British journal of pharmacology 104 (1), 239-245, 1991 | 157 | 1991 |
Novel nonpeptide CCK-B antagonists: design and development of quinazolinone derivatives as potent, selective, and orally active CCK-B antagonists JK Padia, M Field, J Hinton, K Meecham, J Pablo, R Pinnock, BD Roth, ... Journal of medicinal chemistry 41 (7), 1042-1049, 1998 | 135 | 1998 |
Pregabalin may represent a novel class of anxiolytic agents with a broad spectrum of activity MJ Field, RJ Oles, L Singh British journal of pharmacology 132 (1), 1-4, 2001 | 131 | 2001 |
Ca2+ Channel α2-δ Ligands for the Treatment of Neuropathic Pain MJ Field, Z Li, JB Schwarz Journal of medicinal chemistry 50 (11), 2569-2575, 2007 | 92 | 2007 |
Utilization of an Intramolecular Hydrogen Bond To Increase the CNS Penetration of an NK1 Receptor Antagonist VA Ashwood, MJ Field, DC Horwell, C Julien-Larose, RA Lewthwaite, ... Journal of medicinal chemistry 44 (14), 2276-2285, 2001 | 92 | 2001 |
Comparison of the effects of four cholinomimetic agents on cognition in primates following disruption by scopolamine or by lists of objects NMJ Rupniak, MJ Steventon, MJ Field, CA Jennings, SD Iversen Psychopharmacology 99, 189-195, 1989 | 79 | 1989 |
Evaluation of selective NK1 receptor antagonist CI-1021 in animal models of inflammatory and neuropathic pain MI Gonzalez, MJ Field, J Hughes, L Singh Journal of Pharmacology and Experimental Therapeutics 294 (2), 444-450, 2000 | 75 | 2000 |
The tachykinin NK1 receptor antagonist PD 154075 blocks cisplatin-induced delayed emesis in the ferret L Singh, MJ Field, J Hughes, BS Kuo, N Suman-Chauhan, BR Tuladhar, ... European journal of pharmacology 321 (2), 209-216, 1997 | 60 | 1997 |
Ovariohysterectomy in the rat: a model of surgical pain for evaluation of pre-emptive analgesia? MI Gonzalez, MJ Field, S Bramwell, S McCleary, L Singh Pain 88 (1), 79-88, 2000 | 58 | 2000 |
Second Generation “Peptoid” CCK-B Receptor Antagonists: Identification and Development of N-(Adamantyloxycarbonyl)-α-methyl-(R)-tryptophan Derivative (CI … BK Trivedi, JK Padia, A Holmes, S Rose, DS Wright, JP Hinton, ... Journal of medicinal chemistry 41 (1), 38-45, 1998 | 58 | 1998 |