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Charles Birts
Charles Birts
Lecturer in Antibody Therapeutics
Verified email at soton.ac.uk - Homepage
Title
Cited by
Cited by
Year
Targeting tumour proliferation with a small‐molecule inhibitor of AICAR transformylase homodimerization
IB Spurr, CN Birts, F Cuda, SJ Benkovic, JP Blaydes, A Tavassoli
Chembiochem 13 (11), 1628-1634, 2012
1112012
Transcription of click‐linked DNA in human cells
CN Birts, AP Sanzone, AH El‐Sagheer, JP Blaydes, T Brown, A Tavassoli
Angewandte Chemie International Edition 53 (9), 2362-2365, 2014
972014
A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells
CN Birts, SK Nijjar, CA Mardle, F Hoakwie, PJ Duriez, JP Blaydes, ...
Chemical Science 4 (8), 3046-3057, 2013
902013
Catalytic and non-catalytic functions of human IIA phospholipase A2
CN Birts, CH Barton, DC Wilton
Trends in biochemical sciences 35 (1), 28-35, 2010
772010
Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance
CN Birts, R Harding, G Soosaipillai, T Halder, A Azim‐Araghi, M Darley, ...
Biology of the Cell 103 (1), 1-19, 2011
732011
CtBPs promote cell survival through the maintenance of mitotic fidelity
LM Bergman, CN Birts, M Darley, B Gabrielli, JP Blaydes
Molecular and cellular biology 29 (16), 4539-4551, 2009
612009
A catalytically independent physiological function for human acute phase protein group IIA phospholipase A2: cellular uptake facilitates cell debris removal
CN Birts, CH Barton, DC Wilton
Journal of biological chemistry 283 (8), 5034-5045, 2008
392008
p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators
CN Birts, A Banerjee, M Darley, CR Dunlop, S Nelson, SK Nijjar, R Parker, ...
Science signaling 13 (630), eaau9529, 2020
322020
Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1
E Garcia, A Hayden, C Birts, E Britton, A Cowie, K Pickard, M Mellone, ...
Scientific reports 6 (1), 32417, 2016
282016
Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerization
A Banerjee, CN Birts, M Darley, R Parker, AH Mirnezami, J West, ...
Carcinogenesis 40 (7), 871-882, 2019
252019
CtBPs promote mitotic fidelity through their activities in the cell nucleus
CN Birts, LM Bergman, JP Blaydes
Oncogene 30 (11), 1272-1280, 2011
172011
The effects of restricted glycolysis on stem-cell like characteristics of breast cancer cells
A Banerjee, P Arvinrad, M Darley, SA Laversin, R Parker, MJJ Rose-Zerilli, ...
Oncotarget 9 (33), 23274, 2018
112018
Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2+ breast carcinoma
CN Birts, C Savva, SA Laversin, A Lefas, J Krishnan, A Schapira, ...
Scientific Reports 12 (1), 7802, 2022
72022
Age, obesity and hyperglycaemia: Activation of innate immunity initiates a series of molecular interactions involving anionic surfaces leading to COVID-19 morbidity and mortality
CN Birts, DC Wilton
Medical Hypotheses 155, 110646, 2021
62021
Glycolysis, via NADH‐dependent dimerisation of CtBPs, regulates hypoxia‐induced expression of CAIX and stem‐like breast cancer cell survival
M Kreuzer, A Banerjee, CN Birts, M Darley, A Tavassoli, M Ivan, ...
FEBS letters 594 (18), 2988-3001, 2020
52020
Fcγ receptor–mediated cross-linking codefines the immunostimulatory activity of anti-human CD96 antibodies
A Rogel, FM Ibrahim, SM Thirdborough, F Renart-Depontieu, CN Birts, ...
JCI insight 7 (19), 2022
42022
A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells. Chem Sci (Camb) 2013; 4: 3046-57
CN Birts, SK Nijjar, CA Mardle, F Hoakwie, PJ Duriez, JP Blaydes, ...
PUBMED, 0
3
The role of three-dimensional in vitro models in modelling the inflammatory microenvironment associated with obesity in breast cancer
RRR Blyth, CN Birts, SA Beers
Breast Cancer Research 25 (1), 104, 2023
12023
Clinical significance of crown-like structures to trastuzumab response in patients with primary invasive HER2+ breast cancer.
C Savva, CN Birts, SA Laversin, A Lefas, J Krishnan, A Schapira, ...
Journal of Clinical Oncology 39 (15_suppl), e12533-e12533, 2021
12021
Innenrücktitelbild: Transcription of Click‐Linked DNA in Human Cells (Angew. Chem. 9/2014)
CN Birts, AP Sanzone, AH El‐Sagheer, JP Blaydes, T Brown, A Tavassoli
Angewandte Chemie 9 (126), 2543-2543, 2014
12014
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