vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells. S Katzav, D Martin‐Zanca, M Barbacid The EMBO journal 8 (8), 2283-2290, 1989 | 449 | 1989 |
Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs B Margolis, P Hu, S Katzav, W Li, JM Oliver, A Ullrich, A Weiss, ... Nature 356 (6364), 71-74, 1992 | 416 | 1992 |
Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation E Gulbins, KM Coggeshall, G Baier, S Katzav, P Burn, A Altman Science 260 (5109), 822-825, 1993 | 374 | 1993 |
Vav proteins, masters of the world of cytoskeleton organization I Hornstein, A Alcover, S Katzav Cellular signalling 16 (1), 1-11, 2004 | 282 | 2004 |
Cloning of ALL-1, the Locus Involved in Leukemias with the t(4;11)(q21;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13) Chromosome Translocations G Cimino, DT Moir, O Canaani, K Williams, WM Crist, S Katzav, ... Cancer research 51 (24), 6712-6714, 1991 | 238 | 1991 |
A Functional T-Cell Receptor Signaling Pathway Is Required for p95vav Activity J Wu, S Katzav, A Weiss Molecular and cellular biology 15 (8), 4337-4346, 1995 | 235 | 1995 |
Loss of the Amino-Terminal Helix-Loop-Helix Domain of the vav Proto-Oncogene Activates Its Transforming Potential S Katzav, JL Cleveland, HE Heslop, D Pulido Molecular and cellular biology 11 (4), 1912-1920, 1991 | 217 | 1991 |
The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav. S Katzav, M Sutherland, G Packham, T Yi, A Weiss Journal of Biological Chemistry 269 (51), 32579-32585, 1994 | 160 | 1994 |
Oncogenic transformation induces tumor angiogenesis: a role for PAR1 activation YJ Yin, Z Salah, M Maoz, SCE Ram, S Ochayon, G Neufeld, S Katzav, ... The FASEB journal 17 (2), 163-174, 2003 | 148 | 2003 |
Guanine nucleotide exchange factors for RhoGTPases: good therapeutic targets for cancer therapy? G Lazer, S Katzav Cellular signalling 23 (6), 969-979, 2011 | 131 | 2011 |
Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein E Gulbins, KM Coggeshall, C Langlet, G Baier, N Bonnefoy-Berard, ... Molecular and cellular biology 14 (2), 906-913, 1994 | 112 | 1994 |
The haematopoietic specific signal transducer Vav1 is expressed in a subset of human neuroblastomas I Hornstein, E Pikarsky, M Groysman, G Amir, N Peylan‐Ramu, S Katzav The Journal of Pathology: A Journal of the Pathological Society of Great …, 2003 | 88 | 2003 |
Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways M Groysman, I Hornstein, A Alcover, S Katzav Journal of Biological Chemistry 277 (51), 50121-50130, 2002 | 80 | 2002 |
Vav1: an oncogene that regulates specific transcriptional activation of T cells S Katzav Blood 103 (7), 2443-2451, 2004 | 72 | 2004 |
The haematopoietic specific signal transducer Vav1 is aberrantly expressed in lung cancer and plays a role in tumourigenesis G Lazer, Y Idelchuk, V Schapira, E Pikarsky, S Katzav The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009 | 69 | 2009 |
Flesh and blood: the story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies S Katzav Cancer letters 255 (2), 241-254, 2007 | 65 | 2007 |
Single point mutations in the SH2 domain impair the transforming potential of vav and fail to activate proto-vav. S Katzav Oncogene 8 (7), 1757-1763, 1993 | 59 | 1993 |
GTP exchange factor Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation CH Fernández-Espartero, D Ramel, M Farago, M Malartre, CM Luque, ... Journal of cell science 126 (10), 2285-2293, 2013 | 57 | 2013 |
Signalling pathways induced by protease‐activated receptors and integrins in T cells R Bar‐Shavit, M Maoz, Y Yongjun, M Groysman, I Dekel, S Katzav Immunology 105 (1), 35-46, 2002 | 57 | 2002 |
Vav, a GDP/GTP nucleotide exchange factor, interacts with GDIs, proteins that inhibit GDP/GTP dissociation M Groysman, CSN Russek, S Katzav FEBS letters 467 (1), 75-80, 2000 | 54 | 2000 |