| Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits M Niwa, A Kamiya, R Murai, K Kubo, AJ Gruber, K Tomita, L Lu, ... Neuron 65 (4), 480-489, 2010 | 343 | 2010 |
| Adolescent stress–induced epigenetic control of dopaminergic neurons via glucocorticoids M Niwa, H Jaaro-Peled, S Tankou, S Seshadri, T Hikida, Y Matsumoto, ... Science 339 (6117), 335-339, 2013 | 342 | 2013 |
| Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood D Ibi, T Nagai, H Koike, Y Kitahara, H Mizoguchi, M Niwa, H Jaaro-Peled, ... Behavioural brain research 206 (1), 32-37, 2010 | 168 | 2010 |
| Enhanced dopamine function in DISC1‐L100P mutant mice: implications for schizophrenia TV Lipina, M Niwa, H Jaaro‐Peled, PJ Fletcher, P Seeman, A Sawa, ... Genes, Brain and Behavior 9 (7), 777-789, 2010 | 125 | 2010 |
| Vulnerability in early life to changes in the rearing environment plays a crucial role in the aetiopathology of psychiatric disorders M Niwa, Y Matsumoto, A Mouri, N Ozaki, T Nabeshima International Journal of Neuropsychopharmacology 14 (4), 459-477, 2011 | 109 | 2011 |
| Silibinin attenuates amyloid β25–35 peptide-induced memory impairments: implication of inducible nitric-oxide synthase and tumor necrosis factor-α in mice P Lu, T Mamiya, LL Lu, A Mouri, M Niwa, M Hiramatsu, LB Zou, T Nagai, ... Journal of Pharmacology and Experimental Therapeutics 331 (1), 319-326, 2009 | 104 | 2009 |
| Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests S Tomida, T Mamiya, H Sakamaki, M Miura, T Aosaki, M Masuda, M Niwa, ... Nature genetics 41 (6), 688-695, 2009 | 104 | 2009 |
| Silibinin attenuates cognitive deficits and decreases of dopamine and serotonin induced by repeated methamphetamine treatment P Lu, T Mamiya, L Lu, A Mouri, M Niwa, HC Kim, LB Zou, T Nagai, ... Behavioural brain research 207 (2), 387-393, 2010 | 89 | 2010 |
| A novel molecule “shati” is involved in methamphetamine-induced hyperlocomotion, sensitization, and conditioned place preference M Niwa, A Nitta, H Mizoguchi, Y Ito, Y Noda, T Nagai, T Nabeshima Journal of Neuroscience 27 (28), 7604-7615, 2007 | 86 | 2007 |
| Reduction of methamphetamine‐induced sensitization and reward in matrix metalloproteinase‐2 and‐9‐deficient mice H Mizoguchi, K Yamada, M Niwa, A Mouri, T Mizuno, Y Noda, A Nitta, ... Journal of neurochemistry 100 (6), 1579-1588, 2007 | 84 | 2007 |
| Role of matrix metalloproteinase and tissue inhibitor of MMP in methamphetamine‐induced behavioral sensitization and reward: implications for dopamine receptor down‐regulation … H Mizoguchi, K Yamada, A Mouri, M Niwa, T Mizuno, Y Noda, A Nitta, ... Journal of neurochemistry 102 (5), 1548-1560, 2007 | 78 | 2007 |
| An inducer for glial cell line-derived neurotrophic factor and tumor necrosis factor–α protects against methamphetamine-induced rewarding effects and sensitization M Niwa, A Nitta, Y Yamada, A Nakajima, K Saito, M Seishima, L Shen, ... Biological psychiatry 61 (7), 890-901, 2007 | 72 | 2007 |
| DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia M Niwa, T Cash-Padgett, KI Kubo, A Saito, K Ishii, A Sumitomo, ... Molecular psychiatry 21 (11), 1488, 2016 | 68 | 2016 |
| Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory–inhibitory synapse formation in the mature cortex S Seshadri, T Faust, K Ishizuka, K Delevich, Y Chung, SH Kim, M Cowles, ... Nature communications 6 (1), 10118, 2015 | 68 | 2015 |
| Enduring vulnerability to reinstatement of methamphetamine‐seeking behavior in glial cell line‐derived neurotrophic factor mutant mice Y Yan, K Yamada, M Niwa, T Nagai, A Nitta, T Nabeshima The FASEB Journal 21 (9), 1994-2004, 2007 | 61 | 2007 |
| Tumor necrosis factor-α and its inducer inhibit morphine-induced rewarding effects and sensitization M Niwa, A Nitta, Y Yamada, A Nakajima, K Saito, M Seishima, Y Noda, ... Biological psychiatry 62 (6), 658-668, 2007 | 53 | 2007 |
| Subcortical dopaminergic deficits in a DISC1 mutant model: a study in direct reference to human molecular brain imaging H Jaaro-Peled, M Niwa, CA Foss, R Murai, S de Los Reyes, A Kamiya, ... Human molecular genetics 22 (8), 1574-1580, 2013 | 52 | 2013 |
| BDNF overexpression prevents cognitive deficit elicited by adolescent cannabis exposure and host susceptibility interaction H Segal-Gavish, N Gazit, Y Barhum, T Ben-Zur, M Taler, SH Hornfeld, ... Human molecular genetics 26 (13), 2462-2471, 2017 | 45 | 2017 |
| A critical period of vulnerability to adolescent stress: epigenetic mediators in mesocortical dopaminergic neurons M Niwa, RS Lee, T Tanaka, K Okada, SI Kano, A Sawa Human molecular genetics 25 (7), 1370-1381, 2016 | 45 | 2016 |
| The roles of glial cell line-derived neurotrophic factor, tumor necrosis factor-α, and an inducer of these factors in drug dependence M Niwa, A Nitta, K Yamada, T Nabeshima Journal of pharmacological sciences 104 (2), 116-121, 2007 | 45 | 2007 |
