Description
Abstract Despite the widespread application of nickel nanoparticles (Ni NPs) in industrial,
commercial, and biomedical fields, their response to human cells has not been clearly
elucidated. In the study reported here, Ni NPs with a 28 nm diameter were used to study
their interaction with human breast carcinoma (MCF-7) cells. Dose-dependent decreased
cell viability and damaged cell membrane integrity showed the cytotoxic potential of the Ni
NPs. We further found that Ni NPs induce oxidative stress in a dose-dependent manner …