Caffeine Content and Related Gene Expression: Novel Insight into Caffeine Metabolism in Camellia Plants Containing Low, Normal, and High Caffeine …
B Zhu, LB Chen, M Lu, J Zhang, J Han… - Journal of Agricultural …, 2019 - ACS Publications
Caffeine is a crucial secondary metabolic product in tea plants. Although the presence of
caffeine in tea plants has been identified, the molecular mechanisms regulating relevant …
caffeine in tea plants has been identified, the molecular mechanisms regulating relevant …
[HTML][HTML] CsAlaDC and CsTSI work coordinately to determine theanine biosynthesis in tea plants (Camellia sinensis L.) and confer high levels of theanine …
B Zhu, J Guo, C Dong, F Li, S Qiao, S Lin… - Plant biotechnology …, 2021 - ncbi.nlm.nih.gov
Tea, the second most popular nonalcoholic beverage consumed worldwide, is favoured by
billions of consumers due to its special flavour and numerous health benefits (Higdon and …
billions of consumers due to its special flavour and numerous health benefits (Higdon and …
Significantly increased amino acid accumulation in a novel albino branch of the tea plant (Camellia sinensis)
M Lu, J Han, B Zhu, H Jia, T Yang, R Wang, WW Deng… - Planta, 2019 - Springer
Main conclusion A normal tea plant with one albino branch was discovered. RNA sequencing,
albinism phenotype and ultrastructural observations provided a valuable understanding …
albinism phenotype and ultrastructural observations provided a valuable understanding …
[HTML][HTML] ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival
Metabolic pathways are reprogrammed in cancer to support cell survival. Here, we report that
T-cell acute lymphoblastic leukemia (T-ALL) cells are characterized by increased oxidative …
T-cell acute lymphoblastic leukemia (T-ALL) cells are characterized by increased oxidative …
MicroRNA‐31‐5p enhances the Warburg effect via targeting FIH
B Zhu, X Cao, W Zhang, G Pan, Q Yi… - The FASEB …, 2019 - Wiley Online Library
The enhanced expression of miR‐31 has been observed in many human malignancies
including lung cancer, and this microRNA regulates several aspects of oncogenesis. However, …
including lung cancer, and this microRNA regulates several aspects of oncogenesis. However, …
[HTML][HTML] ORP4L extracts and presents PIP2 from plasma membrane for PLCβ3 catalysis: targeting it eradicates leukemia stem cells
W Zhong, M Xu, C Li, B Zhu, X Cao, D Li, H Chen, C Hu… - Cell Reports, 2019 - Elsevier
Leukemia stem cells (LSCs) are a rare subpopulation of abnormal hematopoietic stem cells
(HSCs) that propagates leukemia and are responsible for the high frequency of relapse in …
(HSCs) that propagates leukemia and are responsible for the high frequency of relapse in …
[HTML][HTML] Oxysterol-binding protein-related protein 8 (ORP8) increases sensitivity of hepatocellular carcinoma cells to Fas-mediated apoptosis
W Zhong, S Qin, B Zhu, M Pu, F Liu, L Wang… - Journal of Biological …, 2015 - ASBMB
Human hepatoma (HCC) has been reported to be strongly resistant to Fas-mediated apoptosis.
However, the underlying mechanisms are poorly understood. In this study the function of …
However, the underlying mechanisms are poorly understood. In this study the function of …
Molecular and biochemical characterization of jasmonic acid carboxyl methyltransferase involved in aroma compound production of methyl jasmonate during black …
J Zhang, H Jia, B Zhu, J Li, T Yang… - Journal of Agricultural …, 2021 - ACS Publications
Methyl jasmonate (MeJA), a volatile organic compound, is a principal flowery aromatic compound
in tea. During the processing of black tea, MeJA is produced by jasmonic acid carboxyl …
in tea. During the processing of black tea, MeJA is produced by jasmonic acid carboxyl …
Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice
B Zhu, W Zhong, X Cao, G Pan, M Xu, J Zheng… - Science translational …, 2022 - science.org
Leukemia stem cells (LSCs) propagate leukemia and are responsible for the high frequency
of relapse of treated patients. The ability to target LSCs remains elusive, indicating a need …
of relapse of treated patients. The ability to target LSCs remains elusive, indicating a need …
Discovering high potent Hsp90 inhibitors as antinasopharyngeal carcinoma agents through fragment assembling approach
Hsp90 is a new promising target for cancer treatment. Many inhibitors have been discovered
as therapeutic agents, and some have passed Phase I and II. However, no one is approved …
as therapeutic agents, and some have passed Phase I and II. However, no one is approved …
