Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor
GC Brainard, JP Hanifin, JM Greeson… - Journal of …, 2001 - Soc Neuroscience
… The aim of this study was to establish an action spectrum for light-induced melatonin
suppression that could help elucidate the ocular photoreceptor system for regulating the human …
suppression that could help elucidate the ocular photoreceptor system for regulating the human …
[PDF][PDF] Light during darkness, melatonin suppression and cancer progression
…, RT Dauchy, LA Sauer, JA Krause, GC Brainard - Neuroendocrinology …, 2002 - nel.edu
Over the past few years, we have shown that the surge of melatonin in the circulation during
darkness represents a potent oncostatic signal to tissue-isolated rat hepatoma 7288CTC, …
darkness represents a potent oncostatic signal to tissue-isolated rat hepatoma 7288CTC, …
[PDF][PDF] Ocular input for human melatonin regulation: relevance to breast cancer
G Glickman, R Levin, GC Brainard - Neuroendocrinology Letters, 2002 - instantdaylite.com
… exposure may be a risk factor for cancer is suggested by the suppressive effects of nocturnal
light on pineal melatonin [3,4] and the decrease in melatonin production that has been …
light on pineal melatonin [3,4] and the decrease in melatonin production that has been …
Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humans
…, MD Rollag, JP Hanifin, GC Brainard - Journal of applied …, 2011 - journals.physiology.org
… blue LED light would have increased efficacy for melatonin suppression compared with the
… K white fluorescent light. To accomplish these aims, a within-subject study tested melatonin …
… K white fluorescent light. To accomplish these aims, a within-subject study tested melatonin …
High sensitivity of the human circadian melatonin rhythm to resetting by short wavelength light
SW Lockley, GC Brainard… - The Journal of clinical …, 2003 - academic.oup.com
… nm monochromatic light of equal photon density. Similarly, 460 nm monochromatic light
causes twice the amount of melatonin suppression compared to 555 nm monochromatic light, …
causes twice the amount of melatonin suppression compared to 555 nm monochromatic light, …
Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats
DE Blask, GC Brainard, RT Dauchy, JP Hanifin… - Cancer research, 2005 - AACR
… light/dark cycle entrains circadian melatonin production to a 24-hour cycle, whereas ocular
exposure to light during darkness rapidly suppresses melatonin … of the light exposure (20, 21). …
exposure to light during darkness rapidly suppresses melatonin … of the light exposure (20, 21). …
[PDF][PDF] Dim light adaptation attenuates acute melatonin suppression in humans
…, MD Rollag, GC Brainard - Journal of biological …, 2006 - journals.sagepub.com
… SCN cell sensitivity to light stimuli, relative to various adaptive lighting conditions. These …
light adaptation will dampen the subsequent suppression of melatonin by monochromatic light …
light adaptation will dampen the subsequent suppression of melatonin by monochromatic light …
The spectral sensitivity of human circadian phase resetting and melatonin suppression to light changes dynamically with light duration
…, M Rüger, GC Brainard… - Proceedings of the …, 2022 - National Acad Sciences
… light-induced suppression of melatonin overnight. We show that phase resetting and melatonin
… h) exposure to light but that, at the start of a light exposure, melatonin suppression is best …
… h) exposure to light but that, at the start of a light exposure, melatonin suppression is best …
[PDF][PDF] Inferior retinal light exposure is more effective than superior retinal exposure in suppressing melatonin in humans
…, J Wang, H Cooper, GC Brainard - Journal of biological …, 2003 - journals.sagepub.com
… light-induced suppression of melatonin. The aim of this study was to compare changes in
plasma melatonin levels when light … were exposed to patternless white light for 90 min between …
plasma melatonin levels when light … were exposed to patternless white light for 90 min between …
Short‐wavelength enrichment of polychromatic light enhances human melatonin suppression potency
GC Brainard, JP Hanifin, B Warfield… - Journal of pineal …, 2015 - Wiley Online Library
… In turn, the SCN transmit information about lighting and circadian time … melatonin is synthesized
8. As a result, daily patterns of light exposure entrain the circadian secretion of melatonin…
8. As a result, daily patterns of light exposure entrain the circadian secretion of melatonin…